| Activities in Family | UDP-GalNAc: β-1,4-N-acetylgalactosaminyltransferase (EC 2.4.1.-); |
|---|---|
| Mechanism | inverting (inferred) |
| 3D Structure Status | GT-A |
| Note | Family created after Hirata et al., 2018 (PMID=29374258) who have shown that the human enzyme probably is a b-1,4-N-acetylgalactosaminyltransferase that adds GalNAc to the first mannose residue of GPI anchors; the GTs of this family are characterized by the presence of two transmembrane domains inserted in the GT-A fold; very distant relatedness to GT54 |
| Statistics | GenBank accession (77); Uniprot accession (1); |
| Eukaryota | |||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | |
| UDP-Gal: [GPI-anchor] β-1,4-N-acetylgalactosaminyltransferase (TMEM246; C9orf125) | 2.4.1.- | pubmed |
Homo sapiens | AAH06115.1 AAH33550.1 SJX37796.1 |
Q9BRR3 | ||
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