GlycosylTransferase Family 105

Activities in FamilyDol-P-Man:protein mannosyltransferase (EC 2.4.1.109);
Mechanism inverting (inferred)
NoteFamily of a-mannosyltransferases using Dol-P-Man as the likely donor; first described by Larsen and colleagues [Proc Natl Acad Sci USA 2017 - PMID=28973932]
Statistics GenBank accession (802); Uniprot accession (3);
Eukaryota
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 α-mannosyltransferase (TMTC1; ARG99; Tmtc1) 2.4.1.109   Homo sapiens ACX30004.1
Q8IUR5.3
   
  α-mannosyltransferase (TMTC3; SMILE) 2.4.1.109   Homo sapiens CAD98046.1
BAG63967.1
CAG26973.1
CAH18100.1
CAH18164.1
CAI45938.1
B4DZ55
Q6ZXV5
 
 α-mannosyltransferase (TMTC2) 2.4.1.109   Homo sapiens AAH93852.1
AAH93854.1
BAG37694.1
CAD39165.1
CAL38019.1
Q8N394.1
   
  α-mannosyltransferase (TMTC4; Tmtc4) 2.4.1.109   Homo sapiens BAF83034.1
Q5T4D3.2
A8K2T0  
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