Glycoside Hydrolase Family 5 / Subf 32

Activities in Familyendo-β-1,4-glucanase / cellulase (EC; endo-β-1,4-xylanase (EC; β-glucosidase (EC; β-mannosidase (EC; β-glucosylceramidase (EC; glucan β-1,3-glucosidase (EC; licheninase (EC; exo-β-1,4-glucanase / cellodextrinase (EC; glucan endo-1,6-β-glucosidase (EC; mannan endo-β-1,4-mannosidase (EC; cellulose β-1,4-cellobiosidase (EC; steryl β-glucosidase (EC; endoglycoceramidase (EC; chitosanase (EC; β-primeverosidase (EC; xyloglucan-specific endo-β-1,4-glucanase (EC; endo-β-1,6-galactanase (EC; hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC; β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (6); Uniprot accession (4);
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 Bathy01g00860   Bathycoccus prasinos RCC1105 CCO13990.1     32
 OSTLU_26901   Ostreococcus lucimarinus CCE9901 ABO99132.1 A4S5W1   32
 OSTLU_92070   Ostreococcus lucimarinus CCE9901 ABO94043.1 A4RQL3   32
 Ot01g00930   Ostreococcus tauri OTTH0595 CAL50004.1 Q01GZ0   32
 Ot12g02510   Ostreococcus tauri OTTH0595 CAL57343.1 Q00XQ8   32
 THAPSDRAFT_23753   Thalassiosira pseudonana CCMP1335 EED90640.1     32

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