Glycoside Hydrolase Family 5 / Subf 29

Activities in Sub Familyendoglycosylceramidase (EC;b-galactosylceramidase (EC
Mechanism Retaining
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (72); Uniprot accession (3); PDB accession (1); 3D entries (1); cryst (0)
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3DSubf
 oligogalactosyl-N-acylsphingosine 1,1-β-galactohydrolase / endogalactosylceramidase / endoglycoceramidase III (EGalC;EGCase III) pubmed
Rhodococcus equi M-750 BAF56440.1 A4PCI3   29
  Endoglycoceramidase (EGALC, REQ_10740) pubmed
Rhodococcus hoagii 103S CBH47174.1 A0A3S5Y3Q1
6JYZ[A] 29

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