Glycoside Hydrolase Family 5 / Subf 19

Activities in Sub FamilyMannan exo-β-1,4-mannosidase (EC 3.2.1.-);
β-mannosidase (EC 3.2.1.25);
Mechanism Retaining e
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (278); Uniprot accession (2);
| 1 | 2 | 3 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 SCO0457 or SCF51A.35   Streptomyces coelicolor A3(2) CAB56687.1
NP_624777.1
    19
 FQ762_02240   Streptomyces coelicolor A3(2) CFB_NBC_0001 QFI40727.1     19
 JCM4020_04320   Streptomyces coelicolor JCM 4020 BDD69812.1     19
 HCU77_02060   Streptomyces coelicolor M1154/pAMX4/pGP1416 QKN64404.1     19
 RE436_02120   Streptomyces coelicolor M22 WMT31264.1     19
 M4V62_37540   Streptomyces durmitorensis MS405 UQT60311.1     19
 J4032_16925   Streptomyces formicae 1H-GS9 UNM12975.1     19
 WQO_33325   Streptomyces globisporus C-1027 ALU97802.1     19
 DIJ69_00295   Streptomyces globisporus TFH56 AWL84539.1     19
 GCM10017557_79350   Streptomyces glomeroaurantiacus JCM 4677 BCL33076.1     19
 V9K83_28740   Streptomyces griseoaurantiacus XQ-29 WWY87886.1     19
 ELQ87_38160   Streptomyces griseoviridis F1-27 AZS89429.1     19
 DDJ31_01075   Streptomyces griseoviridis K61 QCN83730.1     19
 V8J11_32625   Streptomyces hygroscopicus subsp. hygroscopicus DSM 41954 WXA10072.1     19
 SHXM_02185   Streptomyces hygroscopicus XM201 AQW48722.1     19
 SIRAN1856   Streptomyces iranensis CDR04864.1     19
 SLITK23_04020   Streptomyces lividans TK23 BDE37157.1     19
 SLIV_35655   Streptomyces lividans TK24 AIJ18007.1     19
 LGI35_11790   Streptomyces longhuiensis BH-MK-02 UDL98902.1     19
 SMALA_6719   Streptomyces malaysiensis DSM 4137 ATL86939.1
QDL69562.1
    19
 R8789_09795   Streptomyces malaysiensis NA3722 WPB89521.1     19
 LC193_11295   Streptomyces marincola SCSIO 64649 UCM88487.1     19
 Dst13   Streptomyces netropsis AIS24858.1     19
 ORF   Streptomyces netropsis CGMCC 4.1650 AHF81543.1     19
 WEB32_30980   Streptomyces netropsis M-141 WXH42422.1     19
 MMU79_12030   Streptomyces olivaceus B-81 WFB83975.1     19
 BC342_33920   Streptomyces pactum KLBMP 5084 AOW90699.1     19
 Spa2297_31190   Streptomyces parvulus 2297 ANJ11065.1     19
 Sfla_4124   Streptomyces pratensis ATCC 33331 ADW05534.1     19
 LIV37_09130   Streptomyces rapamycinicus NRRL 5491 UTP29529.1     19
 M271_08980   Streptomyces rapamycinicus NRRL 5491 AGP53414.1     19
 LJB45_04005   Streptomyces rapamycinicus SRMK07 UTO61581.1     19
 F0345_24875   Streptomyces rutgersensis NBH77 QNE83940.1     19
 I1A49_37365   Streptomyces solisilvae HNM0141 QPI59808.1     19
 CGL27_39810   Streptomyces sp. 11-1-2 ASQ98352.1     19
 SAMN05428941_0512   Streptomyces sp. 2114.2 SDS45321.1     19
 C3K23_31385   Streptomyces sp. 604F QHV88841.1     19
 IPZ55_00070   Streptomyces sp. A10(2020) UNR55130.1     19
 DKB30_35780   Streptomyces sp. Ae707_A7 QNF66421.1     19
 AS97_14090   Streptomyces sp. AgN23 AJZ83591.1     19
 P8A20_23275   Streptomyces sp. Alt3 WLQ66315.1     19
 RPQ02_38065   Streptomyces sp. AM8-1-1 WNO69195.1     19
 M6G09_34965   Streptomyces sp. B146 WGK50404.1     19
 OIM89_00010   Streptomyces sp. BI87 UYX92237.1     19
 OH540_02130   Streptomyces sp. BPPL-273 WHM28876.1     19
 L6J92_17690   Streptomyces sp. CB09030 UOG80919.1     19
 NI25_00975   Streptomyces sp. CCM_MD2014 AIV32265.1     19
 SFR_0080   Streptomyces sp. FR-008 ALM36695.1     19
 KNZ81_00535   Streptomyces sp. G11C(2021) UUD66329.1     19
 B591_00499   Streptomyces sp. GBA 94-10 4N24 ESQ01086.1     19
 B591_29804   Streptomyces sp. GBA 94-10 4N24 ESP95910.1     19
 GR131_31395   Streptomyces sp. GF20 QHC19576.1     19
 LUV23_37505   Streptomyces sp. HNM0561 UHH21480.1     19
 Q3Y68_00755   Streptomyces sp. HUAS CX7 WKX16631.1     19
 NOO62_03925   Streptomyces sp. Je 1-369 WAL93713.1     19
 D1J63_00915   Streptomyces sp. KPB2 AZM73661.1     19
 DKB27_33585   Streptomyces sp. KY2 QNF59087.1     19
 MUK60_40380   Streptomyces sp. LRE541 UPZ33509.1     19
 CFP59_01955   Streptomyces sp. M56 AUA09865.1     19
 K4G22_18495   Streptomyces sp. MA3_2.13 UED85928.1     19
 HUT15_00750   Streptomyces sp. NA03103 QKW59152.1     19
 QFW82_09740   Streptomyces sp. NA07423 WHX17321.1     19
 OSU72_30025   Streptomyces sp. NA13 WAD00113.1     19
 OG428_12110   Streptomyces sp. NBC_01422 WUX97216.1     19
 OG406_37030   Streptomyces sp. NBC_01428 WUX78945.1     19
 OG627_33490   Streptomyces sp. NBC_01429 WUX71376.1     19
 OG627_23410   Streptomyces sp. NBC_01429 WUX69585.1     19
 OG574_35600   Streptomyces sp. NBC_01445 WSE08212.1     19
 L2I08_15115   Streptomyces sp. NBU3104 UKL04150.1     19
 DEH18_16430   Streptomyces sp. NHF165 QHF95182.1     19
 QTO28_11855   Streptomyces sp. P9-2B-1 WJY31661.1     19
 F750_2591   Streptomyces sp. PAMC 26508 AGJ55076.1     19
 MTP06_61240   Streptomyces sp. PLM4 BDH72675.1     19
 LZ559_34595   Streptomyces sp. R527F UIZ17166.1     19
 HYQ63_32695   Streptomyces sp. Rer75 QLH24820.1     19
 SJI45_25920   Streptomyces sp. S399 WPR53951.1     19
 N6H00_34115   Streptomyces sp. S465 WAP59577.1     19
 N6H00_30530   Streptomyces sp. S465 WAP58952.1     19
 D7Y56_11795   Streptomyces sp. S501 QBR06549.1     19
 PS467_34975   Streptomyces sp. SCA4-21 WNF00150.1     19
 CAG99_16915   Streptomyces sp. SCSIO 03032 ARQ70300.1     19
 SACTE_5461   Streptomyces sp. SirexAA-E AEN13270.1     19
 B9S66_30290   Streptomyces sp. SM17 AWL36215.1     19
 V6574_34620   Streptomyces sp. SM1P WYB33408.1     19
 HBB06_18525   Streptomyces sp. SNU607 WKV79981.1     19
 GEV49_00815   Streptomyces sp. SYP-A7193 QFX79614.1     19
 TK78_00435   Streptomyces sp. Tue 6075 Tue6075 APS17566.1     19
 KE639_07181   Streptomyces sp. V17-9 QUW95911.1     19
 EZV63_35465   Streptomyces sp. VN1 QIP74493.1     19
 Q3101_32160   Streptomyces sp. VNUA74 WML84244.1     19
 LXH13_00900   Streptomyces spinosirectus CRSS-Y-16 UIR15668.1     19
 SSPO_020670   Streptomyces sporoclivatus NBRC 100767 BBJ39349.1     19
 GBW32_01455   Streptomyces tsukubensis AT3 QFR91957.1     19
 MMF93_02345   Streptomyces tubbatahanensis DSD3025 UNS95436.1     19
 Ant13   Streptomyces venezuelae ATCC 14583 QEG98948.1
QES25454.1
    19
 DEJ48_35785   Streptomyces venezuelae ATCC 14584 QES38067.1     19
 DEJ49_02370   Streptomyces venezuelae ATCC 14585 QES39973.1     19
 DEJ50_01420   Streptomyces venezuelae ATCC 21782 QES46712.1     19
 R2E43_36850   Streptomyces violaceoruber CGMCC 4.1801 WOZ02732.1     19
 Strvi_3247   Streptomyces violaceusniger Tu 4113 AEM82935.1     19
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