Glycoside Hydrolase Family 59

Activities in Familyβ-galactosidase (EC 3.2.1.23); galactocerebrosidase (EC 3.2.1.46)
Mechanism Retaining (inferred)
ClanGH-A
3D Structure Status( β / α ) 8 (inferred)
Catalytic Nucleophile/BaseGlu (inferred)
Catalytic Proton DonorGlu (inferred)
External resourcesPRINTS;
Statistics GenBank accession (149); Uniprot accession (33); PDB accession (13); 3D entries (1); cryst (0)
Eukaryota
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 galactocerebrosidase (GalC;GALC) 3.2.1.46 Mus musculus AAH86671.1
AAB71823.1
BAA07560.1
BAE32809.1
BAE36334.1
NP_032105.1
P54818
3ZR5[A] 2.10
3ZR6[A] β-D-Galp
2.44
4CCC[A] β-D-Galp-(1-1)-<non_carb>
2.09
4CCD[A] α-D-2-deoxy-Galp-(1-4)-GLU
1.97
4CCE[A] β-D-Galp
2.06
4UFH[A] 2.16
4UFI[A] 2.40
4UFJ[A] 2.20
4UFK[A] D-1-deoxy-GlcpNAc
2.40
4UFL[A] 2.40
4UFM[A] <carb_like_DGJ>
2.40
5N8K[A,B] 3.60
5NXB[A,B] 3.60
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