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Glycoside Hydrolase Family 59

Known Activitiesgalactocerebrosidase (EC 3.2.1.46)
Mechanism Retaining (inferred)
ClanGH-A
3D Structure Status( β / α ) 8 (inferred)
Catalytic Nucleophile/BaseGlu (inferred)
Catalytic Proton DonorGlu (inferred)
External resourcesInterPro; PFAM; PRINTS;
Statistics GenBank accession (59); Uniprot accession (18);
Summary
All (33) Bacteria (18) Eukaryota (15) Characterized (4)
Bacteria
Protein NameEC#OrganismGenBankUniprotPDB/3D
 asp3.1   Actinoplanes sp. SE50/110 CAJ81035.1 Q27GR1  
 AMED_3993   Amycolatopsis mediterranei U32 ADJ45770.1    
 AMED_6431   Amycolatopsis mediterranei U32 ADJ48163.1    
 BIP_14930   Bifidobacterium pseudocatenulatum D2CA CBK72664.1    
 Caci_4910   Catenulispora acidiphila DSM 44928 ACU73770.1    
 Caci_7107   Catenulispora acidiphila DSM 44928 ACU75937.1    
 Caci_3581   Catenulispora acidiphila DSM 44928 ACU72486.1    
 galactosidase (Gal59A;Ccel_1238) (Gal59A)   Clostridium cellulolyticum H10 ATCC 35319 ABG76970.1
ACL75594.1		 Q0PRN1  
 EUS_13590   Eubacterium siraeum 70/3 CBK96504.1    
 ES1_17580   Eubacterium siraeum V10Sc8a CBL34686.1    
 LGG_00051 (Gal59A)   Lactobacillus rhamnosus GG (ATCC 53103) BAI40578.1
CAR85946.1		    
 LGG_00061   Lactobacillus rhamnosus GG (ATCC 53103) BAI40588.1
CAR85956.1		    
 LC705_00043   Lactobacillus rhamnosus Lc 705 CAR88882.1    
 LC705_00053   Lactobacillus rhamnosus Lc 705 CAR88892.1    
 Micau_1959   Micromonospora aurantiaca ATCC 27029 ADL45507.1    
 Pjdr2_4665   Paenibacillus sp. JDR-2 ACT03279.1    
 RUM_07020 (probable fragment)   Ruminococcus sp. 18P13 CBL16905.1    
 SBI_02313   Streptomyces bingchenggensis BCW-1 ADI05434.1    
Eukaryota
Protein NameEC#OrganismGenBankUniprotPDB/3D
 Av_TEL_L_A   Adineta vaga ACD54702.1 B3G4F4  
 Av_TEL_L_B   Adineta vaga ACD54712.1 B3G4G4  
 galactocerebrosidase (CALC) (fragment)   Ateles belzebuth chamek AAF21849.1 Q9TTG3  
 C29E4.10   Caenorhabditis elegans Bristol N2 AAK84495.1
AAK84495.2
AAK84495.2
NP_498726.1		 Q95QT2  
 galactocerebrosidase 3.2.1.46 Canis lupus familiaris AAB37752.1 P54804  
 Unknown (protein for MGC:92561)   Danio rerio AAH83517.1
CAI11729.1		 Q5SNX7
Q5XJ01		  
 ORF   Danio rerio AAH49316.1 Q7ZUD5  
 galactocerebrosidase (GalC) 3.2.1.46 Homo sapiens AAA16645.1
AAA80975.1
AAH36518.1
ACM80397.1
ACM81869.1
BAA04971.1
BAA04972.1
BAA24902.1
BAG57392.1
BAG59160.1
BAG63793.1
BAG64110.1
BAH13778.1
NP_000144.1		 P54803
P54803.1		  
 unnamed protein product (fragment)   Macaca fascicularis BAE89740.1    
 galactocerebrosidase 3.2.1.46 Macaca mulatta AAB58575.1
AAB58576.1		 O02791.1  
 galactocerebrosidase 3.2.1.46 Mus musculus AAB71823.1
AAH86671.1
BAA07560.1
BAE32809.1
BAE36334.1
NP_032105.1		 P54818.1  
 galactosylceramidase   Rattus norvegicus AAR26418.1 Q5YKG1  
 galactocerebrosidase (GalC)   Salmo salar ACI33802.1 B5X3C1  
 Unknown (protein for MGC:145326)   Xenopus (Silurana) tropicalis AAI21270.1 Q0VA39  
 Unknown (protein for IMAGE:7011549 or IMAGE:4202491)   Xenopus laevis AAH81270.1
AAI00188.1		 Q498K0