Glycoside Hydrolase Family 49

Activities in FamilyChaetomorphan endo-β-1,4-(3-sulfo)-arabinanase (EC 3.2.1.-);
Panose α-1,4-glucosidase (EC 3.2.1.-);
Dextranase (EC 3.2.1.11);
Isopullulanase (EC 3.2.1.57);
[inverting] dextran α-1,6-isomaltotriosidase (EC 3.2.1.95);
Mechanism Inverting a
ClanGH-N
3D Structure Statusparallel β-helix
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorAsp
External resourcesCAZypedia;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (78); Uniprot accession (12); PDB accession (7); 3D entries (3); cryst (0)
Bacteria
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 dextranase 1 (Dex1) 3.2.1.11 pubmed
Arthrobacter globiformis T-3044 BAA13596.1 P70744  
 dextranase (Dex) 3.2.1.11 pubmed
Arthrobacter sp. CB-8 BAA00708.1 P39652  
 dextranase 3.2.1.11 pubmed
Arthrobacter sp. G6-4B / 2216 E UYO08508.1    
 dextranase (DexKQ; AoDex) 3.2.1.11 pubmed
Arthrobacter sp. KQ11 / Arthrobacter oxydans KQ11 QDQ17819.1 A0A4V8H044
A0A5J6BCZ4
6NZS[A]
 dextran 1,6-α-isomaltotriosidase (DexT) 3.2.1.95 pubmed
Brevibacterium fuscum var. dextranlyticum BAA76382.1 Q9WXI3  
 sulfated arabinan endo-1,4-β-L-arabinanase (BACPLE_01008) 3.2.1.- pubmed
Phocaeicola plebeius DSM 17135 EDY96565.1 B5CWB8  
 dextranase (Dex2;AoD2;AODex) 3.2.1.11 doi
Pseudarthrobacter oxydans AAX09503.1
ABF74611.1
A9UKG4  
Eukaryota
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 isopullulanase (IpuA; IPU) 3.2.1.57 pubmed
Aspergillus brasiliensis ATCC 9642 (formerly Aspergillus niger ATCC 9642) BAA18971.1
BAA19473.1
O00105 1WMR[A,B]
1X0C[A,B]
2Z8G[A,B]
3WWG[A,B,C,D]
 dextranase (Lsd1) 3.2.1.11 pubmed
Lipomyces starkeyi KSM 22M AAS90631.1 Q2HPE6  
 4-O-α-D-isomaltooligosaccharylmaltooligosaccharide 1,4-α-isomaltooligosaccharohydrolase (IMM-4IH) 3.2.1.- pubmed
Sarocladium kiliense U4520 BDS04947.1    
 dextranase (Dex1) 3.2.1.11 pubmed
Talaromyces minioluteus IMI068219 ABD49214.1 Q27JJ3  
 dextranase (Dex;DexA) (Dex49A) 3.2.1.11 pubmed
Talaromyces minioluteus MUCL 38929 (HI-4) AAB47720.1 P48845 1OGM[X]
1OGO[X]
 dextranase (SMCU-DEX) 3.2.1.11 doi
Talaromyces pinophilus SMCU3-14 ACC95417.1 B2MW82  
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