Glycoside Hydrolase Family 43 / Subf 12

Activities in Familyβ-xylosidase (EC 3.2.1.37); α-L-arabinofuranosidase (EC 3.2.1.55); arabinanase (EC 3.2.1.99); xylanase (EC 3.2.1.8); galactan 1,3-β-galactosidase (EC 3.2.1.145); α-1,2-L-arabinofuranosidase (EC 3.2.1.-); exo-α-1,5-L-arabinofuranosidase (EC 3.2.1.-); [inverting] exo-α-1,5-L-arabinanase (EC 3.2.1.-); β-1,3-xylosidase (EC 3.2.1.-)
Activities in Sub Family
Mechanism Inverting
ClanGH-F
3D Structure Status5-fold β-propeller
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorGlu
NoteMany members have been assigned to subfamilies as described by Mewis et al. (2016) Appl. Environm. Microbiol. in press (PMID: 26729713).
External resourcesCAZypedia;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (646); Uniprot accession (106); PDB accession (4); 3D entries (3); cryst (1)
All (632) Archaea (4) Bacteria (625) unclassified (3) Structure (3 - 1 cryst) Characterized (12)
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 bifunctional endo-β-1,4-xylanase / α-L-arabinofuranosidase (BiXyn10B/BiAra43A;BACINT_04202) (Xyn10B/Ara43A) 3.2.1.55
3.2.1.8
Bacteroides intestinalis DSM 17393 EDV05059.1     12
 α-L-arabinofuranosidase (BACOVA_03421) 3.2.1.55 Bacteroides ovatus ATCC 8483 EDO10788.1     12
 α-L-arabinofuranosidase (BACOVA_03425) 3.2.1.55 Bacteroides ovatus ATCC 8483 EDO10792.1     12
 α-L-arabinofuranoside (Xynb_4;BoGH43A;BACOVA_02654;Bovatus_03073) 3.2.1.55 Bacteroides ovatus ATCC 8483 ALJ47681.1   5JOW[A,B]
5JOX[A,B]
5JOY[A,B]
12
 α-L-arabinofuranoside (Xynb_5;BoGH43B;BACOVA_02656;Bovatus_03074) 3.2.1.55 Bacteroides ovatus ATCC 8483 ALJ47682.1   5JOZ[A,B] 12
 α-L-arabinofuranosidase (AXH-m;AbfA;BAD_0423) 3.2.1.55 Bifidobacterium adolescentis ATCC 15703 BAF39204.1 A1A0H1   12
 α-L-arabinofuranosidase / β-xylosidase (XylB) 3.2.1.37
3.2.1.55
Butyrivibrio fibrisolvens GS 113 AAA63610.1 P45982   12
 β-xylosidase (Xyl;GbtXyl43A) (Xyl43A) 3.2.1.37 Geobacillus thermoleovorans IT-08 ABC75004.1 Q2I2N4 cryst 12
 α-L-arabinofuranosidase (OB2087) 3.2.1.55 Oceanobacillus iheyensis HTE831 BAC14043.1
NP_693008.1
Q8EPL4   12
 arabinoxylan arabinofuranohydrolase (ORF2351) (Ara43A) 3.2.1.55 Prevotella bryantii B14 ADI70680.1 D7SFH6   12
 α-L-arabinofuranosidase / β-xylosidase (deAX) 3.2.1.37
3.2.1.55
uncultured bacterium ACF39706.1 B8QP77   12
 α-L-arabinofuranosidase / β-xylosidase (deAFc) 3.2.1.37
3.2.1.55
uncultured bacterium ABB92159.1 A0S5D8   12
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