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Glycoside Hydrolase Family 18

Activities in FamilyNod factor hydrolase (EC 3.2.1.-);
Chitin exo-β-1,4-N-acetylglucosaminidase (EC 3.2.1.-);
Di-N-acetylchitobiase / reducing-end exo-hexosaminidase (EC 3.2.1.-);
Peptidoglycan endo-β-1,4-N-acetylglucosaminidase (EC 3.2.1.-);
Chitosanase (EC 3.2.1.132);
Chitinase (EC 3.2.1.14);
Chitin exo-β-1,4-N-acetylglucobiosaminidase (EC 3.2.1.200);
[reducing end] exo-chitinase (EC 3.2.1.201);
β-N-acetylhexosaminidase (EC 3.2.1.52);
Mannosyl-glycoprotein endo-β-N-acetylglucosaminidase (EC 3.2.1.96);
Mechanism Retaining e
ClanGH-K
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/Basecarbonyl oxygen of C-2 acetamido group of substrate
Catalytic Proton DonorGlu (experimental)
NoteContains chitinases of classes III and V. Contains non-catalytic proteins such as xylanase inhibitor; concanavalin B; narbonin
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (42170); Uniprot accession (503); PDB accession (428); 3D entries (111); cryst (2)
Summary
Download GH18 (54772) Taxonomic display Structure (111 - 2 cryst) Characterized (433)
| 1 | ... | 124 | 125 | 126 | 127 | 128 | 129 | 130 | 131 | 132 | ... | 332 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ETE54_15710   Escherichia coli BR43-DEC QAV66854.1    
 ETE55_05380   Escherichia coli BR64-DEC QAU99751.1    
 E1A98_17025 (ChiA)   Escherichia coli BW25113 QBM95532.1    
 BW25113_3338 (ChiA)   Escherichia coli BW25113 K-12 AIN33670.1    
 BWG_3029 (ChiA)   Escherichia coli BW2952 K-12 ACR63998.1    
 B6N50_02180   Escherichia coli C ARE45966.1    
 F4W66_16265 (ChiA)   Escherichia coli C27A QGY27030.1    
 TH69_16645   Escherichia coli C41(DE3) AJF78443.1    
 TZ57_16510   Escherichia coli C43(DE3) AKN49196.1    
 C7H11_02430   Escherichia coli C4435 AZU41201.1    
 DK885_02245   Escherichia coli C600 AXL16075.1    
 RG30_20365   Escherichia coli C8 APJ83931.1    
 RG31_02605   Escherichia coli C9 APJ85474.1    
 FMA85_20895 (ChiA)   Escherichia coli CCUG 73778 QGA34957.1    
 AVR67_19180   Escherichia coli CD306 ALX54226.1    
 C5F72_02410   Escherichia coli CFS3292 QHF76716.1    
 BCD20_02455   Escherichia coli CFSAN051542 ARJ94493.1    
 CA899_001935 (ChiA)   Escherichia coli CFSAN061761 QEF52733.1    
 CA898_001975 (ChiA)   Escherichia coli CFSAN061762 QEF57274.1    
 CA901_001960 (ChiA)   Escherichia coli CFSAN061772 QEF71222.1    
 C6668_14410   Escherichia coli CFSAN064036 AVS07506.1    
 c4109 (YheB)   Escherichia coli CFT073 AAN82547.1
NP_755973.1		    
 BMI82_12145   Escherichia coli CH611_eco ARQ24463.1    
 DF192_18130   Escherichia coli CJ236 QBP03431.1    
 EAF06_10275   Escherichia coli CM IVRI KOL-1 QIF74155.1    
 BWI83_10620   Escherichia coli Combat13F7 AUY75836.1    
 BWI82_13315   Escherichia coli Combat2C1 AUY71214.1    
 HP434_02015 (ChiA)   Escherichia coli CP131_Sichuan QKF08445.1    
 EAH50_04225   Escherichia coli CP53 AYN88502.1    
 HP432_02410 (ChiA)   Escherichia coli CP61_Sichuan QKF17471.1    
 DS732_24450   Escherichia coli cq9 AXO09240.1    
 ATL78_22335   Escherichia coli CQSW20 ALQ75041.1    
 BVL38_02075   Escherichia coli CRE1493 AUL61807.1    
 CU076_02695   Escherichia coli CREC-532 ATX17919.1    
 CU080_05515   Escherichia coli CREC-629 ATW96057.1    
 CV83906_2376 (ChiA)   Escherichia coli CV839-06 AUP44972.1    
 D9E17_02095 (ChiA)   Escherichia coli CVM N17EC0211 QEP55328.1    
 D9E71_02095 (ChiA)   Escherichia coli CVM N17EC0320 QEQ81748.1    
 D9I79_01995 (ChiA)   Escherichia coli CVM N17EC1164 QEP59606.1    
 F1L16_02035 (ChiA)   Escherichia coli CVM N55972 QEP87178.1    
 F1L19_02040 (ChiA)   Escherichia coli CVM N62675 QEP78193.1    
 RG43_02120   Escherichia coli D10 APK42150.1    
 RG35_03000   Escherichia coli D2 APK04687.1    
 RG36_21135   Escherichia coli D3 APK12627.1    
 RG37_19330   Escherichia coli D4 APK17276.1    
 RG39_12400   Escherichia coli D6 APK25460.1    
 RG40_13630   Escherichia coli D7 APK30316.1    
 ERL60_01950   Escherichia coli D72 QBJ99269.1    
 RG41_22835   Escherichia coli D8 APK36513.1    
 RG42_20160   Escherichia coli D9 APK40849.1    
 DLJ62_02575   Escherichia coli DA33133 AWO19126.1    
 DLJ63_25925   Escherichia coli DA33135 AWO27949.1    
 HO395_15960 (ChiA)   Escherichia coli Dam/Dcm QJZ09547.1    
 EcDH1_0375   Escherichia coli DH1 ACX38065.1
BAJ45072.1		    
 ADS71_17120   Escherichia coli DH1Ec095 AKR22145.1    
 ADZ27_17120   Escherichia coli DH1Ec104 AKR26499.1    
 ADZ28_17120   Escherichia coli DH1Ec169 AKR30976.1    
 DS1UA2014_18750   Escherichia coli DS1 ASO02397.1    
 EAS44_18280   Escherichia coli DSM 30083 = JCM 1649 = ATCC 11775 AYO73917.1    
 C4J63_02770   Escherichia coli DTU-1 AVD30567.1    
 RIMDOsaka138_40560   Escherichia coli E138 BBU77112.1    
 EIMP302_43640   Escherichia coli E302 BBU92226.1    
 DQW89_02260   Escherichia coli E308 AXT79236.1    
 C2U19_02035   Escherichia coli E41-1 AWR72177.1    
 DMI84_02065   Escherichia coli E706 AXT74663.1    
 FX998_12530 (ChiA)   Escherichia coli Ec-050 QEJ63124.1    
 E4Z89_01910 (ChiA)   Escherichia coli EC-129 QCJ58345.1    
 FOZ67_02215 (ChiA)   Escherichia coli EC2 QGQ13592.1    
 EQK40_02260   Escherichia coli EC25 QAR39947.1    
 G5V60_02010 (ChiA)   Escherichia coli EC28 QIE80235.1    
 C0R78_04985   Escherichia coli Ec40 AUO40033.1    
 BAY41_03860   Escherichia coli EC590 ANO28065.1    
 D3W51_01910   Escherichia coli ECCHD184 AYP00491.1    
 CRG85_01910   Escherichia coli ECCNB20-2 AZW02858.1    
 CI675_0001895 (ChiA)   Escherichia coli ECCTRSRTH03 QDJ86303.1    
 D3W53_02015   Escherichia coli ECCWS199 AXZ71626.1    
 ChiA, partial (fragment)   Escherichia coli ECG01 QIE49598.1    
 ChiA, partial (fragment)   Escherichia coli ECG05 QIE49599.1    
 ChiA, partial (fragment)   Escherichia coli ECG09 QIE49601.1    
 ChiA, partial (fragment)   Escherichia coli ECG13 QIE49604.1    
 ChiA, partial (fragment)   Escherichia coli ECG15 QIE49605.1    
 ChiA, partial (fragment)   Escherichia coli ECG16 QIE49606.1    
 ChiA, partial (fragment)   Escherichia coli ECG17 QIE49607.1    
 ChiA, partial (fragment)   Escherichia coli ECG18 QIE49608.1    
 ChiA, partial (fragment)   Escherichia coli ECG22 QIE49609.1    
 ChiA, partial (fragment)   Escherichia coli ECG23 QIE49610.1    
 ChiA, partial (fragment)   Escherichia coli ECG26 QIE49611.1    
 ChiA, partial (fragment)   Escherichia coli ECG28 QIE49612.1    
 ChiA, partial (fragment)   Escherichia coli ECG43 QIE49614.1    
 ChiA, partial (fragment)   Escherichia coli ECG46 QIE49615.1    
 ChiA, partial (fragment)   Escherichia coli ECG65 QIE49616.1    
 FNW43_20330 (ChiA)   Escherichia coli ecMN1F QFG19236.1    
 WM90_00870   Escherichia coli Eco889 ANK50454.1    
 E3Z24_01900 (ChiA)   Escherichia coli ECOL-18-VL-LA-PA-Ryan-0026 QDM02873.1    
 BE937_27980   Escherichia coli Ecol_244 AQW20168.1    
 BE964_13005   Escherichia coli Ecol_276 AQV25306.1    
 BE933_06880   Escherichia coli Ecol_422 AQV34736.1    
 A4R37_16085   Escherichia coli Ecol_448 AMX41363.1    
 BE959_10720   Escherichia coli Ecol_517 AQV40592.1    
 BE966_15230   Escherichia coli Ecol_542 AQV47009.1    
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