Glycoside Hydrolase Family 189

Activities in Familyβ-1,2-glucan synthetase (elongation) (EC 2.4.1.391);
β-1,2-glucan synthetase (cyclization) (EC 2.4.1.397);
Mechanism Retaining e
3D Structure Status( α / α ) 6 barrel
NoteCreated after Tanaka et al. [PMID=38300345] who demonstrated the b-glucosyltransferase activity on b-1,2-glucooligosaccharides of the multimodular protein Thit_1831 in Thermoanaerobacter italicus Ab9, that comprises an N-terminal GT84 and a C-terminal GH94. Family with remote homology to GH144/clan-S, always found in such multimodular architectures.
External resourcesCAZypedia;
Statistics GenBank accession (2842); Uniprot accession (5); PDB accession (5); 3D entries (2); cryst (0)
Bacteria
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 cyclic β-1,2-glucan synthase (Atu2730;ChvB;cgs) 2.4.1.391
2.4.1.397
Agrobacterium fabrum str. C58 AAK88447.2
AAK88447.1
AAL43711.1
NP_355662.1
NP_533395.1
Q7CWD9
8RF0[A] β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-α-D-Glcp-(1-0)-TYR
β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-3)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-3)-D-1-deoxy-Glcp
3.40
8RF9[A] 3.28
8RFE[A] β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-D-1-deoxy-Glcp
3.80
8RFG[A] β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-D-1-deoxy-Glcp
β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-D-1-deoxy-Glcp
β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-D-1-deoxy-Glcp
3.35
 β-1,2-glucooligosaccharide:β-glucosyltransferase (Thit_1831) 2.4.1.391
2.4.1.397
Thermoanaerobacter italicus Ab9 ADD03073.1 D3T4C1
8WY1[A,B,C,D] 3.90
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