Glycoside Hydrolase Family 13 / Subf 40

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (434); Uniprot accession (59); PDB accession (5); 3D entries (1); cryst (0)
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 α-glucosidase / maltase (MalT;AO090038000234) 3.2.1.20 Aspergillus oryzae RIB40 BAB59003.1
BAE64051.1
CBF79201.1
Q2U314
Q96WT4
  40
 α-1,6-glucosidase / glucodextranase (GlcA) 3.2.1.70 Aspergillus parasiticus SU-1 AAF26276.1
AAS66027.1
CBF79170.1
Q6UEE8   40
 α-glucosidase (Mal2;Mal1) 3.2.1.20 Candida albicans AAA34350.2
AAQ53127.1
AAV03584.1
C4YN96
Q02751
  40
 α-glucosidase (maltase mal22) 3.2.1.20 Kluyveromyces lactis CAB46746.1
CBF79221.1
Q9Y844   40
 α-glucosidase (MAL1) 3.2.1.20 Pichia angusta CBS4732 AAF69018.1
CBF79216.1
Q9P8G8   40
 α-glucosidase (Mal6S;Mal62) 3.2.1.20 Saccharomyces carlsbergensis CB11 AAA34757.1
AAQ53125.1
CBF79232.1
P07265   40
 oligo-α-1,6-glucosidase 3.2.1.10 Saccharomyces cerevisiae D-346 BAD00094.1 E1AFY6
P53051
Q76CZ0
  40
 α-glucosidase (Ima4;Fsp2;YJL221C) 3.2.1.20 Saccharomyces cerevisiae S288c CAA83990.1
ADK27713.1
CAA89517.1
CBF79245.1
NP_012314.1
E1AFY9
P0CW40
P0CW41
P40439
  40
 α-glucosidase (Ima2;IMA2;YOL157c) 3.2.1.20 Saccharomyces cerevisiae S288c CAA99179.1
AAQ53126.1
ADK27711.1
NP_014485.1
E1AFY7
Q08295
  40
 oligo-α-1,6-glucosidase / isomaltase (Ima1;IMA1;Fsp2;YGR287c) 3.2.1.10 Saccharomyces cerevisiae S288c BAA07818.1
ADK27710.1
CAA97319.1
CAA97321.1
CBF79247.1
NP_011803.1
E1AFY6
P53051
3A47[A]
3A4A[A]
3AJ7[A]
3AXH[A]
3AXI[A]
40
 α-glucosidase (Mal1S;Mal12;YGR292W) 3.2.1.20 Saccharomyces cerevisiae S288c CAA97325.1
ADK27712.1
NP_011808.1
E1AFY8
P53341
  40
 α-glucosidase (AGL;Mal3S;Mal32;YBR299W;YBR2117) 3.2.1.20 Saccharomyces cerevisiae S288c CAA85264.1
CAA00532.1
NP_009858.1
P38158   40
 α-glucosidase (Ima3;IMA3;YIL172C) 3.2.1.20 Saccharomyces cerevisiae S288c CAA87020.1
NP_012096.1
E1AFY9
P0CW40
P0CW41
P40439
  40
 α-glucosidase (Ima5;IMA5;YJL216c) 3.2.1.20 Saccharomyces cerevisiae S288c CAA83995.1
CAA89513.1
CBF79243.1
NP_012319.1
P40884   40
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