Activities in Sub Family	[retaining] α-amylase (EC 3.2.1.1); [retaining] maltogenic α-amylase (EC 3.2.1.133); [retaining] neopullulanase (EC 3.2.1.135); [retaining] cyclomaltodextrinase (EC 3.2.1.54);
Mechanism	Retaining a
Clan	GH-H
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Asp (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	New: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resources	CAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)	MEGAZYME; PROZOMIX;
Statistics	GenBank accession (870); Uniprot accession (25); PDB accession (10); 3D entries (6); cryst (0)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
DR864_18300		Runella rosea HYN0085	AXE19549.1			36
Runsl_1888		Runella slithyformis DSM 19594	AEI48312.1			36
DTQ70_24910		Runella sp. SP2	AYQ36470.1			36
C2869_05425		Saccharobesus litoralis CCB-QB4	AWB65917.1			36
C2869_03160		Saccharobesus litoralis CCB-QB4	AWB65493.1			36
Sde_0589 (PulB)		Saccharophagus degradans 2-40	ABD79853.1 CBF79140.1			36
QFX18_18430		Saccharophagus degradans FZY0027	WGO97987.1			36
L21SP2_0103		Salinispira pacifica L21-RPul-D2	AHC13547.1			36
L21SP2_0548		Salinispira pacifica L21-RPul-D2	AHC13980.1			36
L21SP5_03143		Salinivirga cyanobacteriivorans L21-Spi-D4	ALO16758.1			36
MM221_11130		Salipaludibacillus sp. LMS25	UTR13206.1			36
BBEV_1693 (TreC)		Salisediminibacterium beveridgei MLTeJB	AOM83054.1			36
L21SP3_00623		Sedimentisphaera cyanobacteriorum L21-RPul-D3	AQQ08832.1			36
STSP1_00333		Sedimentisphaera salicampi ST-PulAB-D4	ARN55964.1			36
BleG1_3658		Shouchella lehensis G1	AIC96205.1			36
H9Q77_15205		Simiaoa sunii NSJ-8	QNM02375.1			36
CATMQ487_05510		Sphaerotilus sp. FB-5	BDI03581.1			36
NCTC13534_05049		Sphingobacterium daejeonense NCTC13534	VTQ06480.1			36
QYC40_00695		Sphingobacterium sp. BN32	WKK58761.1			36
GFH32_00970		Sphingobacterium sp. dk4302	QGA24980.1			36
PZ892_15845		Sphingobacterium sp. WM	WFB63132.1			36
LZK98_19235		Sphingomonas cannabina DM2-R-LB4	UIJ45152.1			36
FPZ24_05915		Sphingomonas panacisoli HKS19	QDZ07076.1			36
G8759_28320		Spirosoma aureum BT328	QIP16267.1			36
GJR95_14420		Spirosoma endbachense I-24	QHV96129.1			36
H3H32_24190		Spirosoma foliorum KCTC 72228	QMW01054.1			36
Slin_0347		Spirosoma linguale DSM 74	ADB36411.1			36
AWR27_11365		Spirosoma montaniterrae DY10	AQG79872.1			36
LQ777_07335		Spirosoma oryzicola RHs26	UHG92708.1			36
CWM47_12465		Spirosoma pollinicola HA7	AUD02572.1			36
SD10_05305		Spirosoma radiotolerans DG5A	AKD58344.1			36
EXU85_28115		Spirosoma sp. KCTC 42546	QDK82269.1			36
LN737_06730		Spirosoma sp. KNUC1025	UFH55797.1			36
HU175_11450		Spirosoma sp. KUDC1026	QKZ13214.1			36
HU175_11455		Spirosoma sp. KUDC1026	QKZ13215.1			36
WBJ53_23335		Spirosoma sp. SC4-14	WXC13916.1			36
HNV11_04700		Spirosoma taeanense TS118	QJW88726.1			36
SAMN06298216_1780		Spirosomataceae bacterium TFI 002	SOE21307.1			36
STAUR_1293		Stigmatella aurantiaca DW4/3-1	ADO69097.1			36
KX935_04560 (fragment)		Streptobacillus moniliformis BK14232	QXW66456.1			36
KX935_04555 (fragment)		Streptobacillus moniliformis BK14232	QXW65115.1			36
KX935_04550 (fragment)		Streptobacillus moniliformis BK14232	QXW65114.1			36
KX935_04565 (fragment)		Streptobacillus moniliformis BK14232	QXW65116.1			36
Smon_1342		Streptobacillus moniliformis DSM 12112	ACZ01787.1			36
CEP89_05040 (fragment)		Streptobacillus moniliformis FDAARGOS_310	AVL43738.1			36
CEP89_05010		Streptobacillus moniliformis FDAARGOS_310	AVL43218.1			36
CEP89_05045 (fragment)		Streptobacillus moniliformis FDAARGOS_310	AVL43222.1			36
PXH66_07020		Synoicihabitans lomoniglobus LMO-M01	WED66599.1			36
BK010_07045		Tenericutes bacterium MO-XQ	AUD63357.1			36
BK011_07515		Tenericutes bacterium MZ-XQ	AUD65547.1			36
Theco_1349		Thermobacillus composti KWC4	AGA57508.1			36
KDW03_04115		Thermospira aquatica F1F22	URA10995.1			36
α-amylase (AmyA;TM1840;Tmari_1848) (Amy13A)	3.2.1.1	Thermotoga maritima MSB8	CAA72194.1 AAD36902.1 AGL50772.1 AHD18270.1 AKE29589.1 CAZ78695.1 CBF78892.1 NP_229636.1	G4FGM5 P96107 Q9S5Y2		36
THMB_1883		Thermotoga maritima Tma100	AKE31460.1			36
THMC_1883		Thermotoga maritima Tma200	AKE27714.1			36
CTN_0766		Thermotoga neapolitana DSM 4359	ACM22942.1			36
α-amylase (Tpet_0965)	3.2.1.1	Thermotoga petrophila RKU-1	ABQ46983.1 AHZ45717.1	A0A059TXD8 A5ILB0	5M99[A,B]	36
Tnap_0587		Thermotoga petrophila RKU-10	ADA66683.1			36
CELL2_04990		Thermotoga sp. Cell2	AIY88297.1			36
TRQ2_0983		Thermotoga sp. RQ2	ACB09333.1			36
TRQ7_05260		Thermotoga sp. RQ7	AJG40862.1			36
EW093_04480		Thiospirochaeta perfilievii	QEN03987.1			36
EW093_09855		Thiospirochaeta perfilievii	QEN05000.1			36
Trebr_0689		Treponema brennaborense DSM 12168	AEE16131.1			36
IWA51_03030		Treponema peruense RCC2812	QQA01604.1			36
DYE49_00220		Treponema rectale CHPA	QOS38963.1			36
DYE50_09185		Treponema ruminis RU1	QSI02738.1			36
DYE50_02370		Treponema ruminis RU1	QSI01425.1			36
TRSA_25380		Treponema saccharophilum JCM 32279	BDC97439.1			36
TRSA_13130		Treponema saccharophilum JCM 32279	BDC96214.1			36
HRI97_10780		Treponema socranskii subsp. buccale ATCC 35534	UTD03500.1			36
H9I35_05730		Treponema sp. Marseille-Q4132	QNL98238.1			36
RCV51_12815		Truepera radiovictrix CIP 108686	WMT56886.1			36
Trad_1442		Truepera radiovictrix DSM 17093	ADI14564.1			36
HLK68_08420		Turicibacter sanguinis MOL361	QJS19266.1			36
alpha amylase, catalytic domain protein (fragment)		uncultured bacterium	AMP56231.1			36
α-amylase (AmyA)	3.2.1.1	uncultured bacterium	AAP49335.1 CBF79177.1	Q6XR91		36
α-amylase (AmyM)	3.2.1.1	uncultured bacterium	AAQ89599.1 ALJ10569.1 CAZ78880.1 CBF79168.1	Q6TXT5		36
GH13_36-CBM58		uncultured bacterium	CAK9711902.1			36
ORF2		uncultured bacterium	AFK82655.1			36
RF679_12760		Undibacterium sp. 20NA77.5	WMW79516.1			36
HYG85_12220		Vallitalea guaymasensis Ra1766G1	QUH29629.1			36
WAL19_33770		Waltera intestinalis 19YCFAH0.3Co2	BEU19541.1			36
α-amylase	3.2.1.1	Xanthomonas campestris K-11151	BAA07401.1 CAZ78877.1 CBF79165.1	Q60102		36
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