Activities in Sub Family	[retaining] α-amylase (EC 3.2.1.1); [retaining] maltogenic α-amylase (EC 3.2.1.133); [retaining] neopullulanase (EC 3.2.1.135); [retaining] cyclomaltodextrinase (EC 3.2.1.54);
Mechanism	Retaining a
Clan	GH-H
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Asp (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	New: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resources	CAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)	MEGAZYME; PROZOMIX;
Statistics	GenBank accession (870); Uniprot accession (25); PDB accession (10); 3D entries (6); cryst (0)

Bacteria
Protein Name	EC#	Reference	Organism	GenBank	Uniprot	PDB/3D	Subf
maltogenic α-amylase (EUR_01860)	3.2.1.133	pubmed	Agathobacter rectalis DSM 17629	CBK89424.1	D6E1Y4	7JJN[A,B]	36
α-amylase (AmyA)	3.2.1.1		Anaerobranca gottschalkii	AAW32491.1	Q5I942		36
α-amylase (BMW-amylase)	3.2.1.1		Bacillus sp. WHO	ABU54057.1	A7U965		36
α-amylase (AmyF)	3.2.1.1		Bacillus sp. WS06	AAX84031.1 CAZ78870.1	Q4Z8Q4		36
α-amylase / neopullulanase (SusG; BtSusG; BT3698; BT_3698) (outer membrane)	3.2.1.1 3.2.1.135	pubmed pubmed pubmed pubmed	Bacteroides thetaiotaomicron VPI-5482	AAO78803.1 AAB42174.1 CAZ78746.1 NP_812609.1	Q45772 Q8A1G3	3K8K[A,B] 3K8L[A,B] 3K8M[A,B] 6BS6[A,B]	36
α-amylase / neopullulanase (SusG; BtSusG; BT3698; BT_3698) (outer membrane)	3.2.1.1 3.2.1.135	pubmed pubmed pubmed pubmed	Bacteroides thetaiotaomicron VPI-5482	AAO78803.1 AAB42174.1 CAZ78746.1 NP_812609.1	Q45772 Q8A1G3	3K8K[A,B] 3K8L[A,B] 3K8M[A,B] 6BS6[A,B]	36
maltogenic α-amylase (CoMA)	3.2.1.133	pubmed	Corallococcus sp. EGB	AVC05420.1	A0A2L1CF09		36
α-amylase 3 (AmyC)	3.2.1.1	pubmed	Dictyoglomus thermophilum	CAA34072.1 CAZ78893.1 CBF79228.1	P14899		36
g-cyclodextrin-specific cyclodextrinase (Cda)	3.2.1.54		Evansella clarkii 7364	BAH14969.1	B9A1J7		36
α-amylase A (AmyA;Hore_14740)	3.2.1.1		Halothermothrix orenii H 168	AAN52525.1 ACL70223.1 CAZ78883.1 CBF79188.1	B8CY54 Q8GPL8	1Q76[nd] 1WML[nd] 1WZA[A]	36
α-amylase (formerly neopullulanase)	3.2.1.1 3.2.1.135	pubmed pubmed	Paenibacillus polymyxa CECT 155	AAD05199.1 CAZ78891.1	Q9ZAP8		36
α-amylase / neopullulanase (Npl)	3.2.1.1	URL	Paenibacillus sp. KCTC8848P	AAL07400.1 CAZ78884.1 CBF79194.1	Q93C66		36
α-amylase	3.2.1.1	pubmed	Priestia megaterium NCIB 11568	CAA30247.1 ACH26139.1 CAZ78896.1 CBF79230.1	P20845		36
α-amylase (Bman2)	3.2.1.1	doi	Priestia megaterium NL3	AWO14641.1	A0A2U8ZUR1		36
α-amylase (RBL263_00780; Amy5)	3.2.1.1	pubmed	Ruminococcus bromii L2-63	SPE91476.1 CBL15129.1	A0A2N0UXJ4 D4L684	7JJT[A]	36
α-amylase (AmyA;TM1840;Tmari_1848) (Amy13A)	3.2.1.1	URL	Thermotoga maritima MSB8	CAA72194.1 AAD36902.1 AGL50772.1 AHD18270.1 AKE29589.1 CAZ78695.1 CBF78892.1 NP_229636.1	G4FGM5 P96107 Q9S5Y2		36
α-amylase (Tpet_0965)	3.2.1.1		Thermotoga petrophila RKU-1	ABQ46983.1 AHZ45717.1	A0A059TXD8 A5ILB0	5M99[A,B]	36
α-amylase (AmyA)	3.2.1.1		uncultured bacterium	AAP49335.1 CBF79177.1	Q6XR91		36
α-amylase (AmyM)	3.2.1.1	pubmed	uncultured bacterium	AAQ89599.1 ALJ10569.1 CAZ78880.1 CBF79168.1	Q6TXT5		36
α-amylase	3.2.1.1		Xanthomonas campestris K-11151	BAA07401.1 CAZ78877.1 CBF79165.1	Q60102		36
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