Glycoside Hydrolase Family 138

Activities in Familyrhamnogalacturonan α-1,2-galacturonohydrolase (EC 3.2.1.173)
Mechanism retaining
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu
Catalytic Proton DonorGlu
NoteCreated after Ndeh et al., Nature (2017) 544(7648):65-70 (PMID=28329766); mechanism and structure after Labourel et al., JBC (2019) (PMID=30877196)
External resourcesCAZypedia;
Statistics GenBank accession (169); Uniprot accession (4); PDB accession (4); 3D entries (1); cryst (0)
Bacteria
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 rhamnogalacturonan α-1,2-galacturonohydrolase 3.2.1.173 Phocaeicola paurosaccharolyticus   A0A4V8GZY3
A0A4V8GZY4
A0A4V8GZY5
6HZE[B] β-D-GalpA
2.70
6HZF[A,B] 1.95
6HZG[A] α-D-GalpA
β-D-GalpA
1.60
6HZE[A] β-D-GalpA
2.70
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