Activities in Family	endo-β-1,4-xylanase (EC 3.2.1.8); endo-β-1,3-xylanase (EC 3.2.1.32)
Mechanism	Retaining
Clan	GH-C
3D Structure Status	β-jelly roll
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	formerly known as cellulase family G
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (2235); Uniprot accession (426); PDB accession (146); 3D entries (36); cryst (2)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
xylanase A (XlnA;BcX)	3.2.1.8	Bacillus circulans	AAS31723.1 AAM08360.1 AAS31734.1 ABH92518.1 ACK26680.1 ACQ19008.1 ACR92575.1 CAA30553.1	P09850 Q8RMN8	1BCX[A] β-D-Xylp-(1-4)-β-D-Xylp 1.20 1BVV[A] β-D-Xylp-(1-4)-α-D-Xylp2F-(1-4)-GLU 2.20 1C5H[A] 1.60 1C5I[A] β-D-Xylp-(1-4)-α-D-Xylp2F-(1-4)-GLU 2.53 1HV0[A] 1.60 1HV1[A] 1.67 1XNB[A] 1.85 1XNC[A] 2.10 2B42[B] 1.82 2BVV[A] 2.50 3HD8[B,D] 1.67 3LB9[A,B,C] 3.41 3VZJ[A,B,C,D] 1.70 3VZK[A,B] 1.88 3VZL[A,B,C,D] 2.30 3VZM[A] β-D-Xylp-(1-4)-α-D-Xylp2F-(1-4)-GLU 1.66 3VZN[A,B] β-D-Xylp-(1-4)-α-D-Xylp2F-(1-4)-GLU 1.90 3VZO[A] β-D-Xylp-(1-4)-α-D-Xylp2F-(1-4)-GLU 2.30
xylanase J (XynJ)	3.2.1.8	Bacillus sp. 41M-1	BAA82316.1 AAS31755.1	Q9RC94	2DCJ[A,B] 1.10 2DCK[A] 2.28 6KJL[A,B] 1.9 6KKA[A,B] 1.42
xylanase (ATBXYL-C;XylC1;XylC2;XylC3)	3.2.1.8	Bacillus sp. NCL 87-6-10	AEP40124.1 AEP40122.1 AEP40123.1		2F6B[A,B] 3.00
xylanase		Bacillus sp. NCL 87-6-10			2NQY[B] β-D-Xylp β-D-Xylp-(1-1)-<non_carb> 2.15 2NQY[A] β-D-Xylp β-D-Xylp-(1-1)-<non_carb> 2.15
xylanase (Xyn11A-LC) (Xyn11A)	3.2.1.8	Bacillus sp. SN5	AGL92443.1		4IXL[A,B] 1.50
xylanase	3.2.1.8	Bacillus subtilis B230		Q7SID8	1IGO[A] 1.30
xylanase A (XynA;BsxA;BsXynA;BSU18840)	3.2.1.8	Bacillus subtilis subsp. subtilis str. 168	CAB13776.1 AAA22897.1 AAB84458.1 AAM08359.1 ABH92520.1 ACK26682.1 ACQ19010.1 ACR92566.1 AIY93198.1 AQR81879.1 AQR86093.1 CAA84276.1 NP_389765.1	P18429	1AXK[A] 2.12 1XXN[A] 2.29 2B45[X] 1.81 2B46[X] β-D-Xylp-(1-4)-β-D-Xylp 2.47 2DCY[A,B,C,D,E] 1.90 2DCZ[A,B] 4.58 2QZ3[A,B] β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp NMR 2Z79[A,B] 1.77 3EXU[A,B] 1.62 5K9Y[A,B] 2.90
xylanase B (XynB;XynB3;229B)	3.2.1.8	Dictyoglomus thermophilum RT46B.1	AAC46361.1	P77853	1F5J[A,B] 2.10
xylanase A (XynA)	3.2.1.8	Geobacillus stearothermophilus 236	AAB72117.1	P45705	cryst
xylanase (BadX;Xyl11)	3.2.1.8	Salipaludibacillus agaradhaerens AC13	CAB42305.1 ABE26517.1 ABE26518.1 CAA03091.1		1H4G[A,B] β-D-Xylp-(1-4)-α-D-Xylp2F-(1-4)-GLU 2.20 1H4H[A,B,C,D] β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-α-D-Xylp 2.79 1QH6[A,B] β-D-Xylp-(1-4)-α-D-Xylp2F-(1-4)-GLU 1.55 1QH7[A,B] β-D-Xylp 2.50
xylanase B (XlnB;XlnB1;XlnB2)	3.2.1.8	Streptomyces lividans 1326	AAC06114.2 AAS31736.1 ABH92525.1 ACQ19015.1	P26515	5EJ3[A,B] 1.10
xylanase (SoxB) (fragment)		Streptomyces olivaceoviridis ATCC 23630	AHK22787.1		7DFM[A,B,C,D] 1.99 7DFN[A,B,C,D] β-D-Xylp-(1-4)[α-L-Araf-(1-3)]-β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp 2.30 7DFO[A,B,C,D,E,F,G,H,I] α-D-GlcpA4Me-(1-2)-β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp β-D-Xylp-(1-4)-β-D-Xylp β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp β-D-Xylp-(1-4)[α-D-GlcpA4Me-(1-2)]-β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp 2.35
xylanase (Xyl1)	3.2.1.8	Streptomyces sp. S38	CAA67143.1	Q59962	1HIX[A] 1.15
xylanase (Xyl11;Xyl20;Tx-Xyn;TxXYN;Tx-Xyl;Tx-Xyn11;G11)	3.2.1.8	Thermobacillus xylanilyticus D3	CAJ87325.1	Q14RS0	cryst
endo-β-1,4-xylanase (Xyl11;TfGH11)	3.2.1.8	Thermobifida fusca NTU22	AAV64879.1	Q5RZ98	3ZSE[A] β-D-Xylp-(1-4)-α-D-Xylp2F-(1-4)-GLU 2.20
endo-β-1,4-xylanase (XynA;Xyn;NfXyn;NfXyn11) (Xyn11A)	3.2.1.8	Thermopolyspora flexuosa DSM43186 / ATCC35864	CAD48747.1 AAO97628.1 AAQ80269.1 AAS23965.1 ACC29940.1	Q8GMV7	1M4W[A] 1.43 3B5L[B] 2.80 3MF6[A] 1.74 3MF9[A] 1.79 3MFA[A] 2.00 3MFC[A] 1.55
glycoside hydrolase		uncultured bacterium	AMO13186.1		7AX7[A] 2.75 7AY3[A] 2.65 7AYL[A,B] 1.35 7AYP[A] 1.34
xylanase (X0012;Xyn12)	3.2.1.8	uncultured bacterium	ADD82898.1	D4PAK8	5GV1[A] 1.90 5GY8[A] 1.90 5GY9[A,B] 1.4 5GYA[A,B] 1.55 5GYB[A] 2.00 5GYC[A] 2.24 5GYE[A] 2.10 5GYF[A] 1.64 5GYG[A,B] 2.29 5GYH[A] 2.60 5GYI[A] 1.50
xylanase (EvXyn11fl) (Xyn11)	3.2.1.8	uncultured bacterium	ACB87630.1	B2LWN3	2VGD[A] β-D-Xylp-(1-4)-β-D-Xylp β-D-Xylp-(1-4)[α-L-Ribf-(1-3)]-β-D-Xylp-(1-4)-β-D-Xylp 1.64 2VUJ[A] 1.50 2VUL[A] 1.70
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
xylanase C / xylanase 3 (XynC)	3.2.1.8	Aspergillus kawachii	AAC60542.1 AAS31748.1 ABH92517.1 ACQ19007.1 BAA03576.1	P33557	1BK1[A] 1.90 3RI8[A] 2.81 3RI9[A] 1.60
endo-β-1,4-xylanase 1 (XynA;XylA;XynII;ExlA;AnxA;An14g07390)	3.2.1.8	Aspergillus niger CBS 513.88	CAA01470.1 AAZ66797.1 ABH92516.1 ACK26693.1 ACQ19006.1 ACR92608.1 CAK46731.1	P55329	1T6G[C,D] 2.00 1UKR[A,B,C,D] 1.85 2QZ2[A] β-D-Xylp-(1-4)-β-D-Xylp β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp 1.5 6QE8[A] 2.50
xylanase 11A (Xyn11A)	3.2.1.8	Chaetomium thermophilum CBS730.95	AAR67679.1 AAE69548.1 AAQ73530.1 CAD48749.1	Q6UN40 Q8J1V6	1H1A[A,B] 1.72 1XNK[A,B] β-D-Xylp4S-(1-4)-β-D-Xylp4S-(1-4)-α-D-Xylp4S-(1-1)-methyl 1.70
xylanase (Xyl2)	3.2.1.8	Fusarium oxysporum f. sp. lycopersici 4287	KNB08954.1		5JRM[A] 1.60 5JRN[A] β-D-Xylp-(1-1)-methyl 1.15
NECHADRAFT_106153	3.2.1.8	Fusarium vanettenii 77-13-4	XP_003050975.1		6Y0H[A] 0.97
xylanase A / 11A (XynA;XylA;Xyl11A;NpXyn11A) (Xyn11A)	3.2.1.8	Neocallimastix patriciarum	CAA46498.1 AAB23454.1 AAS31749.1 CAB58524.1 CAB58525.1 CAB58526.1 CAB58527.1 CAB58530.1 CAB58531.1 CAB58532.1	P29127	2C1F[A] 1.70 2VG9[A] 1.80
endo-β-1,4-xylanase (XynC;CDBFV;Xyn-CDBFV;XynCDBFV)	3.2.1.8	Neocallimastix patriciarum	AAF14365.1 AAE61565.1	Q9UV68	3WP4[A] 2.8 3WP5[A] 2.50 3WP6[A] β-D-Xylp-(1-4)-β-D-Xylp β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp 2.40
xylanase	3.2.1.8	Paecilomyces variotii BAINIER	AAS31744.1	P81536	1PVX[A] NMR
xylanase (Xyl1)	3.2.1.8	Scytalidium acidophilum	AAQ22691.1	Q6VAY1	3M4F[A,B,C,D] 2.30
xylanase 11C (XylC;TcXylC)	3.2.1.8	Talaromyces cellulolyticus CF-2612	BAO51921.1		3WP3[A,B] 1.38 5HXV[A,B,C,D,E,F,G,H,I,J, 1.62
endo-β-1,4-xylanase C (XynC;PfXynC)	3.2.1.8	Talaromyces funiculosus IMI-134756 / ATCC 62998 / 8/403	CAC15487.1 AAP60299.1 CAC07798.1	Q9HFH0	1TE1[B] 2.79
xylanase A (XynA;XynA2;XynI)	3.2.1.8	Thermomyces lanuginosus SSBP / ATCC 46882 / DSM10635	AAB94633.1 AAE10889.1 AAS31745.1 ACR92582.1 ACY69861.1	O43097	1YNA[A] 1.80
xylanase		Trichoderma harzianum E58	AAS31741.1 ABH92529.1 ACK26691.1 ACQ19019.1 ACR92591.1	P48793	1XND[A] 2.40
xylanase II (XynII;XYNII) (partial)		Trichoderma longibrachiatum			3AKP[A,B] 1.61 3AKQ[A] 2.20 3AKR[A] 1.72 3AKS[A] 1.01 3AKT[A,B] 2.20 2JIC[A] 2.30
xylanase 1 (Xyn1;XYNI)	3.2.1.8	Trichoderma reesei	AAE16058.1 AAS31742.1 ABH92530.1 ACK26677.1 ACQ19020.1 ACR92612.1 CAA49294.1	P36218	1XYN[A] 2.13
endo-β-1,4-xylanase 2 (Xyn2;XYNII;Xyn11;EX2;BD-11) (Xyn11A)	3.2.1.8	Trichoderma reesei RUT-C30	AAB29346.1 AAE16057.1 AAS31743.1 ABH92531.1 ABH92533.1 ABH92534.1 ABH92538.1 ABH92539.1 ABH92540.1 ABH92541.1 ACB38137.1 ACB59312.1 ACK26676.1 ACQ19021.1 ACR92589.1 ACR92590.1 ACS11409.1 CAA49293.1	B2CZF9 P36217 Q02244	1ENX[A,B] 1.94 1RED[A,B] β-D-Xylp-(1-1)-<non_carb> 2.49 1REE[A,B] β-D-Xylp-(1-1)-<non_carb> 2.20 1REF[A,B] β-D-Xylp-(1-1)-<non_carb> 1.63 1XYO[A,B] 1.17 1XYP[A,B] 2.00 2D97[A] 1.87 2D98[A] 2.15 2DFB[A] 17.00 2DFC[A] NMR 3LGR[A] 2.30 4HK8[A] β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp 2.40 4HK9[A] β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp 1.67 4HKL[A] 2.37 4HKO[A] NMR 4HKW[A] β-D-Xylp-(1-4)-β-D-Xylp-(1-1)-<non_carb> β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-α-D-Xylp 2.89 4S2D[A] 1.05 4S2F[A] 1.70 4S2G[A] 1.80 4S2H[A] 2.44 4XPV[A] 1.28 4XQ4[A,B] 1.70 4XQD[A,B] 1.44 4XQW[A] 1.43 5K7P[A] 1.48 5ZF3[A] β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp 2.29 5ZH0[A] 2.40 5ZH9[A] 1.8 5ZII[A] β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-α-D-Xylp 2.09 5ZIW[A] 1.90 5ZKZ[A] β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp 1.80 5ZO0[A] 1.90 6JUG[A] 2.13 6JWB[A] β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp 1.80 6JXL[A] β-D-Xylp-(1-4)-β-D-Lyxp-(1-4)-β-D-Xylp 1.70 6JZP[A] 1.60 6K9O[A] 3.60 6K9R[A] β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp 2.07 6KW9[A] 1.90 6KWD[A] β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp 1.90 6KWF[A] β-D-Xylp β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp 1.78 6KWG[A] β-D-Xylp-(1-4)-β-D-Lyxp-(1-4)-β-D-Xylp 2.00
unclassified
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
exo-β-1,4-xylanase	3.2.1.-	unidentified	5VQJ_A		5VQJ[A] 2.3
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