Activities in Family	[retaining] reducing end exo-β-mannosidase (EC 3.2.1.-); β-mannosidase (EC 3.2.1.25); Endo-β-1,4-mannanase (EC 3.2.1.78);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Created based on Zhang et al. (2008) J. Biol. Chem. 283, 31551-31558 (PMID:18755688)
External resources	CAZypedia;
Statistics	GenBank accession (2004); Uniprot accession (19); PDB accession (14); 3D entries (3); cryst (0)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
PZB72_21540		Catalinimonas niigatensis NBRC 109829	WPP49255.1
Celf_3695		Cellulomonas fimi ATCC 484	AEE47802.1
NCTC7547_03776		Cellulomonas fimi NCTC7547	VEH37032.1
Celgi_0113		Cellulomonas gilvus ATCC 13127	AEI10645.1
GXP71_15690		Cellulomonas sp. H30R-01	QHT58446.1
GC089_00720		Cellulomonas sp. JZ18	QGQ20796.1
Celal_0945		Cellulophaga algicola DSM 14237	ADV48270.1
M666_02570		Cellulophaga baltica 18	AIZ40555.1
M601_016915		Cellulophaga baltica 4	WFO15461.1
M667_02575		Cellulophaga baltica NN016038	AIY12189.1
A5M85_04415		Cellulophaga lytica DAU203	APU09554.1
Celly_0812		Cellulophaga lytica DSM 7489	ADY28644.1
SR888_15960		Cellulophaga lytica DSMZ 7489	WQG77177.1
QYR09_04590		Cellulophaga lytica EKP101	WKB82311.1
IX49_03870		Cellulophaga lytica HI1	AIM59697.1
PBN93_04045		Cellulophaga omnivescoria MSK1	WBU90187.1
H0I23_12005		Cellulophaga sp. HaHaR_3_176	QWX83171.1
H0I24_10595		Cellulophaga sp. HaHa_2_1	QXP50603.1
H0I25_04550		Cellulophaga sp. HaHa_2_95	QXP57074.1
Clole_2499		Cellulosilyticum lentocellum DSM 5427	ADZ84205.1
Clole_3359		Cellulosilyticum lentocellum DSM 5427	ADZ85049.1
EKH84_15130		Cellulosilyticum sp. WCF-2	QEH69651.1
EKH84_20025		Cellulosilyticum sp. WCF-2	QEH70549.1
H1Q78_09070		Cellulosimicrobium cellulans 2020WEIHUA_E	UKJ65864.1
CBR64_01720 (fragment)		Cellulosimicrobium cellulans PSBB019	ARU53565.1
NMQ07_13560		Cellulosimicrobium cellulans TL2	UTT61173.1
IPP08_02415		Chlorobiota bacterium	QQS67048.1
IPP08_07990		Chlorobiota bacterium	QQS65716.1
Cag_1895		Chlorobium chlorochromatii CaD3	ABB29145.1
OQ292_17355		Chondrinema litorale WSW3-B12	UZR93619.1
CMC5_072870		Chondromyces crocatus Cm c5	AKT43060.1
GRFL_1777		Christiangramia flava JLT2011	APU68501.1
GFO_3614		Christiangramia forsetii KT0803	CAL68552.1
C7S20_03935		Christiangramia fulva SH35	AVR44479.1
MKO06_03165		Gramella oceanisediminis GC03-9	UNG09069.1
LPB144_09075		Christiangramia salexigens LPB0144	APG61441.1
T8I65_14760		Christiangramia sp. OXR-203	WPY98425.1
JNO48_13815		Clostridiales bacterium XBB3002	QTE68242.1
BN1096_340081		Clostridioides difficile	CDS84521.1
DA413_05335		Clostridioides difficile 020474	AYD06176.1
DA418_04565		Clostridioides difficile 020477	AYC92922.1
DA422_05335		Clostridioides difficile 020482	AYC96634.1
DA426_14590		Clostridioides difficile 020688	AYD11484.1
DA430_05320		Clostridioides difficile 020695	AYD13367.1
DA432_05280		Clostridioides difficile 020696	AYD17032.1
DA434_05290		Clostridioides difficile 020709	AYD20674.1
DA436_05270		Clostridioides difficile 020711	AYD24240.1
C3348_05330		Clostridioides difficile 08-00495	AVB49019.1
TW87_07390		Clostridioides difficile 08ACD0030	AMM58561.1
C3353_05330		Clostridioides difficile 09-00072	AVB59951.1
C3349_05330		Clostridioides difficile 10-00071	AVB56324.1
C3351_05335		Clostridioides difficile 10-00078	AVB63569.1
C3352_05340		Clostridioides difficile 10-00253	AVB67117.1
C3347_05330		Clostridioides difficile 12-00008	AVB33073.1
C3350_05340		Clostridioides difficile 12-00011	AVB52699.1
KFK07_05290		Clostridioides difficile 2015	QUP84827.1
JMW46_14580		Clostridioides difficile 2016	QQY75366.1
CD630_10320		Clostridioides difficile 630	CAJ67873.1
CDIF630_01168		Clostridioides difficile 630	AJP10718.1
CDIF630erm_01168		Clostridioides difficile 630 delta erm	ARE61941.1
CD630DERM_10320		Clostridioides difficile 630Derm	CEJ97590.1
JMW47_06420		Clostridioides difficile 7009825	QQY73786.1
BN1095_630085		Clostridioides difficile 7032989	CDT67566.1
BN1097_350086		Clostridioides difficile 7032994	CDS84955.1
C4J70_04660		Clostridioides difficile AK	AVI11600.1
CDIF1296T_01123		Clostridioides difficile ATCC 9689 = DSM 1296	AKP42007.1
BZ168_13170		Clostridioides difficile BR81	AQU10567.1
DF008_01220		Clostridioides difficile CBA7204	QHF99300.1
C3W74_05325		Clostridioides difficile CD-10-00484	AVB40416.1
DDG63_05625		Clostridioides difficile CD161	AWH80490.1
JMW48_09940		Clostridioides difficile CD1801	QQY67436.1
JMW54_10720		Clostridioides difficile CD2315	QQY66179.1
JMW51_15605		Clostridioides difficile CD4401	QQY63032.1
JMW55_00310		Clostridioides difficile CD9001	QQY60175.1
JMW49_03370		Clostridioides difficile CD9301	QQY57332.1
JMW52_15175		Clostridioides difficile CD9501	QQY52756.1
JMW50_02010		Clostridioides difficile CD9701	QQY50313.1
DDG61_05895		Clostridioides difficile CDT4	AWH76723.1
GLV80_14060		Clostridioides difficile CFSAN096664	QOX88032.1
CGC51_05270		Clostridioides difficile DH/NAP11/106/ST-42	ASN88735.1
CDIF101085_01023		Clostridioides difficile DSM 101085	QPK99330.1
CDIF102859_01119		Clostridioides difficile DSM 102859	AXU26945.1
CDIF102860_01210		Clostridioides difficile DSM 102860	AXU30804.1
CDIF102978_01210		Clostridioides difficile DSM 102978	AXU34592.1
DSM105001_01054		Clostridioides difficile DSM 105001	QNG64052.1
CDIF27639_01038		Clostridioides difficile DSM 27639	AXB63821.1
CDIF28669_01057		Clostridioides difficile DSM 28669	AXU63719.1
CDIF28670_01140		Clostridioides difficile DSM 28670	AXU74748.1
CDIF29020_01048		Clostridioides difficile DSM 29020	AXU67378.1
CDIF29627_01098		Clostridioides difficile DSM 29627	AXU45587.1
CDIF29629_01090		Clostridioides difficile DSM 29629	AXU49286.1
CDIF29632_01025		Clostridioides difficile DSM 29632	AXU82200.1
CDIF29688_01051		Clostridioides difficile DSM 29688	AXU78416.1
CDIF29745_01034		Clostridioides difficile DSM 29745	AXU85879.1
CDIF29747_01006		Clostridioides difficile DSM 29747	AXU89549.1
A6J95_04960		Clostridioides difficile FDAARGOS_267	ARC14376.1
FOC31_08840		Clostridioides difficile FDAARGOS_723	QGS39498.1
JMW53_13375		Clostridioides difficile M120	QQY45583.1
FQN08_05100		Clostridioides difficile Mta-79	QEK80609.1
ERS445050_00917		Clostridioides difficile NCTC13307	CKG91704.1
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