Glycoside Hydrolase Family 110

Activities in Family	α-1,3-D-galactosidase (EC 3.2.1.-); Blood group B α-1,3-galactosidase (EC 3.2.1.-);
Mechanism	Inverting a
3D Structure Status	parallel β-helix
Catalytic Nucleophile/Base	Not known
Catalytic Proton Donor	Asp
Note	Created following Liu et al. (2007) Nature Biotechnol 25:454-64 (PMID: 17401360); mechanism described by Liu et al. (PMID: 18227066)
External resources	CAZypedia;
Statistics	GenBank accession (1080); Uniprot accession (9); PDB accession (7); 3D entries (3); cryst (0)


Bacteria
Protein Name	EC#	Reference	Organism	GenBank	Uniprot	PDB/3D
exo-α-galactosidase variant A (GlaA)	3.2.1.-	pubmed	Bacteroides fragilis	CAJ33350.1	Q5L7M8
α-1,3-galactosidase (BfGal110A; BF4251) (Gal110A)	3.2.1.-	pubmed	Bacteroides fragilis NCTC 9343	CAH09922.1	Q5L7M8
α-1,3-galactosidase (GlaB; BfGal110B; BF0845) (Gal110B)	3.2.1.-	pubmed	Bacteroides fragilis NCTC 9343	CAJ33351.1 CAH06588.1	Q5LGZ8
α-1,3-galactosidase (GlaA; BtGal110A; BT3160; BT_3160) (Gal110A)	3.2.1.-	pubmed	Bacteroides thetaiotaomicron VPI-5482	AAO78266.1 CAJ33352.1	Q8A2Z5
α-1,3-galactosidase (GlaB; BtGal110B; BT4251; BT_4251) (Gal110B)	3.2.1.-	pubmed	Bacteroides thetaiotaomicron VPI-5482	AAO79356.1 CAJ33353.1	Q89ZX0
α-galactosidase (AgaBb)	3.2.1.-	pubmed	Bifidobacterium bifidum JCM 1254	BAM76380.1	L8B3G2	8YK1[A,B,C] 8YK2[A,B] 8YK3[A,B]
α-1,3-galactosidase (Gla; SgGal110A)	3.2.1.-	pubmed	Peterkaempfera griseoplana 2357	CAJ90659.1	B1V8K7
α-1,3-galactosidase (PdGH110B; EU511_08540)	3.2.1.-	pubmed	Pseudoalteromonas distincta		A0A8I3AZV8 A0A8I3AZV9	7JW4[B] 7JWF[A,B,C,D] 7JW4[A]
α-1,3-galactosidase (Gla; SaGal110A; SAV7268) (Gal110A)	3.2.1.-	pubmed	Streptomyces avermitilis MA-4680 = NBRC 14893	CAJ33349.1 BAC74979.1	Q826C5
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