Carbohydrate Esterase Family 1

Known Activities	acetyl xylan esterase (EC 3.1.1.72); cinnamoyl esterase (EC 3.1.1.-); feruloyl esterase (EC 3.1.1.73); carboxylesterase (EC 3.1.1.1); S-formylglutathione hydrolase (EC 3.1.2.12)
3D Structure Status	(a/b/a)-sandwich
Note	Family CE1 also contains lots of other esterases such as PHB depolymerases.
External resources	InterPro;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (2336); Uniprot accession (1137); PDB accession (16); 3D entries (7); cryst (0)

Summary

All (2100) Archaea (2) Bacteria (1995) Eukaryota (85) unclassified (18) Structure (7 ) Characterized (40)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
feruloyl esterase I (FaeI;CGSCsYakCAS_18248) (Fae1A)	3.1.1.73	Cellulosilyticum ruminicola CGMCC 1.5065	ACZ98598.1	D2KFJ6
feruloyl esterase II (FaeII;CGSCsYakCAS_18995)	3.1.1.73	Cellulosilyticum ruminicola CGMCC 1.5065	ACZ98648.1	D2KFP6
feruloyl esterase D (Fae1;XylD;XynD;CJA_3282) (Fee1B)	3.1.1.73	Cellvibrio japonicus Ueda107	ACE85652.1 CAA41727.1	B3PEI0 Q51815
xylanase Z / feruloyl esterase (XynZ;LX3)	3.1.1.73 3.2.1.8	Clostridium thermocellum	AAA23286.1 AAR39815.1	P10478.3	1JJF[A] 1JT2[A]
xylanase Z / feruloyl esterase (XynZ;Cthe_1963) (Xyn10Z)	3.1.1.73 3.2.1.8	Clostridium thermocellum ATCC 27405	ABN53181.1	P10478
xylanase Y / feruloyl esterase (XynY;LX5) (Xyn10B)	3.1.1.73 3.2.1.8	Clostridium thermocellum YS	AAR39814.1 CAA58242.1	P51584	1GKK[A,B] 1GKL[A,B] 1WB4[A,B] 1WB5[A,B] 1WB6[A,B]
jk1937 (CmtA)	2.3.1.122	Corynebacterium jeikeium K411 NCTC 11915	CAI38118.1	Q4JST9
ferulic acid esterase (FaeB)	3.1.1.73	Lactobacillus buchneri PTA-6138	ADI72730.1	D7RU29
carboxylesterase (EstA)	3.1.1.1	Lactococcus lactis subsp. cremoris CNRZ253	AAM90699.1	Q8KWI9
antigen 85-A / mycolyl transferase (FbpA) (fragment)	2.3.1.122	Mycobacterium avium subsp. paratuberculosis ATCC 19698	CAE48278.1	Q70E87
6-O-acylglucoside esterase / glucoside 6-O-acyltransferase (FbpC;FbpC2;Ag85C;Rv0129c)	2.3.1.- 3.1.1.-	Mycobacterium tuberculosis H37Rv	AAB22871.1 CAA40506.1 CAE55244.1 NP_214643.1	P31953	1DQY[A] 1DQZ[A,B] 1VA5[A] 3HRH[A,B]
antigen 85A (FbpA)	2.3.1.122	Mycobacterium ulcerans ITM 5150	AAG31743.1 CAC40861.1	P58248
cellulose acetate esterase (CaeA)	3.1.1.-	Neisseria sicca SB	BAJ21448.1	E1CAJ7
esterase (MesA)	3.1.1.-	Pasteurella multocida	AAG34997.1	Q9EZ25
endo-β-1,4-xylanase / ferulic acid esterase (PRU_2728) (Xyn10D-Fae1A)	3.1.1.73 3.2.1.8	Prevotella ruminicola 23	ACN78954.1 ADE83639.1	D5EY13
xylanase B (XynB)	3.2.1.8	Ruminococcus albus	BAB39493.1	Q9AJB4
endoxylanase E (XynE)	3.2.1.8	Ruminococcus flavefaciens 17	CAB93667.1	Q9L3K3
xylanase 1 (Xyn1)	3.2.1.8	Ruminococcus sp.	AAR39816.1 CAA90271.1	Q59790
feruloyl esterase (Est1;Est1-Txyl;Tx-Est1)	3.1.1.73	Thermobacillus xylanilyticus XE	ADK73591.1
lipase (RlipE1)	3.1.1.-	uncultured bacterium Rlip1	ACM91105.1	C0K075
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
feruloyl esterase (Fae1A) (Fae1A)	3.1.1.73	Anaeromyces mucronatus YE505	ADZ47894.1
acetyl xylan esterase (AceA;AxeA)	3.1.1.72	Aspergillus awamori	BAA13434.1 BAA13434.2	Q92194
acetyl xylan esterase	3.1.1.72	Aspergillus ficuum	AAK60128.1	Q96W96
acetyl esterase (AnAXE;AN6093.2)	3.1.1.-	Aspergillus nidulans FGSC A4	ABF50875.1 EAA58068.1
feruloyl esterase (AnFAE;AN5267.2)	3.1.1.73	Aspergillus nidulans FGSC A4	EAA62427.1	C8VH20
acetyl xylan esterase A (Axe;AxeA)	3.1.1.72	Aspergillus niger	CAA01634.1
acetyl xylan esterase (AxeA; AO090011000745)	3.1.1.72	Aspergillus oryzae RIB40	BAD12626.1 BAE65196.1
acetylxylan esterase (Axe3)	3.1.1.72	Chrysosporium lucknowense C1	ADZ98864.1
carbohydrate esterase (Est1;CcEst1;CC1G_06945.1)	3.1.1.72 3.1.1.73	Coprinopsis cinerea 5338	BAJ10857.1	D7URW8
feruloyl esterase (Fae1A;MtFae1a;MYCTH_96478)	3.1.1.73	Myceliophthora thermophila ATCC 42464	AEO62008.1
bifunctional acetylxylan esterase / endo-β-1,4-xylanase (AxeS20E;XynS20E)	3.1.1.72 3.2.1.8	Neocallimastix patriciarum	ACL68347.1	B8YG19
feruloyl esterase B (FaeB;Fae-1) (NCU09491.1/B22K18.040)	3.1.1.73	Neurospora crassa OR74A	CAC05587.1 CAE75726.1 XP_329850.1	Q9HGR3 Q9HGR3.2
feruloyl esterase D (FaeD;FaeD-3.544;NCU08785.1)	3.1.1.73	Neurospora crassa OR74A	XP_330902.1
cinnamoyl esterase (FaeB)	3.1.1.-	Penicillium funiculosum IMI134756	AAP60304.1 CAC14144.1	Q9HE18
acetyl xylan esterase (AxeI;AcXEI)	3.1.1.72	Penicillium purpurogenum MYA-38	AAM93261.1	Q8NJP6
acetylxylan esterase	3.1.1.72	Phanerochaete chrysosporium BKM-F-1767	AEX99751.1
cinnamoyl esterase (EstA)	3.1.1.-	Piromyces equi	AAD45376.1 CAB69283.1 CAB69284.1	Q9Y871
unclassified
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
xylanase (xynGR40) (probable fragment)	3.2.1.8	uncultured microorganism	ADN44261.1	E2FJN9
acetyl xylan esterase (R.17;R.17-1) (fragment)	3.1.1.72	unidentified microorganism	CAJ19109.1	Q2YI93
acetyl xylan esterase (R.35;R.35-4) (probable fragment)	3.1.1.72	unidentified microorganism	CAJ19122.1	Q2YI81

Footnotes

Experimental characterization exclusively covers enzyme activities at present. If you are aware of any missing experimental characterization that should be mentioned here, we encourage you to send your comment and support of the experimental evidence, including an electronic copy or appropriate link to the support material (i.e., article(s), thesis, database, etc), to cazy@afmb.univ-mrs.fr.