Carbohydrate Esterase Family 17

Activities in FamilyAcetylmannan esterase (EC 3.1.1.-);
NoteFamily created after Michalak et al. [PMID:32170022], who demonstrated the acetylmannan esterase activity of ROSINTL182_05471 (RiCEX) protein from Roseburia intestinalis L1-82. Annotation in CAZy will be restricted to family members displaying >40% identity to the characterized member(s), to distinguish acetylmannan esterases from other esterases possibly acting on non-carbohydrate substrates.
Statistics GenBank accession (36); Uniprot accession (1); PDB accession (2); 3D entries (1); cryst (0)
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 acetyl β-mannan-esterase (specific to 2-O-acetylations) (RiCE17; RiCEX; ROSINTL182_05471) 3.1.1.- Roseburia intestinalis L1-82 EEV02614.1 C7G6F8
6HFZ[A,B,C,D] 1.75
6HH9[A,B,C,D] β-D-Manp-(1-4)-β-D-Manp-(1-4)-β-D-Manp

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