Carbohydrate-Binding Module Family 51

Activities in FamilyModules of approx. 150 residues found attached to various enzymes from families GH2, GH27, GH31, GH95, GH98 and GH101 . Binding to galactose and to blood group A/B-antigens demonstrated in the case of C. perfringens GH95CBM51 and GH98CBM51 respectively [Gregg KJ et al. (2008) J. Biol. Chem. 283:12604-13 PMID: 18292090].
3D Structure Statusβ-sandwich
NoteAlso know as NPCBM domains
Statistics GenBank accession (477); Uniprot accession (74); PDB accession (8); 3D entries (4); cryst (0)
Bacteria
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 blood group A- and B-cleaving endo-β-galactosidase (Endo-ABase;EabC) 3.2.1.- Clostridium perfringens ATCC 10543 AAR84225.1 Q6RUF5
2VNG[A,B] α-D-GalpNAc-(1-3)[α-L-Fucp-(1-2)]-β-D-Galp
1.4
2VNO[A,B] α-D-Galp-(1-3)[α-L-Fucp-(1-2)]-β-D-Galp
1.45
2VNR[A] 1.55
 α-1,2-L-fucosidase (Afc3;CPF_2129) 3.2.1.63 Clostridium perfringens ATCC 13124 ABG82552.1 Q0TP83
2VMG[A] β-D-Galp-(1-1)-methyl
1.90
2VMH[A] 1.50
2VMI[A] 1.70
 endo-β-1,4-galactosidase (CGSSp3BS71_10403;Sp3GH98;EABase) (blood-group A/B-antigen-specific) 3.2.1.102 Streptococcus pneumoniae SP3-BS71 EDK74349.1 A5LBQ0
2YGL[A,B] 2.10
2YGM[A,B] α-D-Galp-(1-3)[α-L-Fucp-(1-2)]-β-D-Galp-(1-4)-β-D-GlcpNAc
2.35
 endo-β-1,4-galactosidase (CGSSp3BS71_10403;Sp3GH98;EABase) (blood-group A/B-antigen-specific) 3.2.1.102 Streptococcus pneumoniae SP3-BS71 EDK74349.1 A5LBQ0
2YGL[A,B] 2.10
2YGM[A,B] α-D-Galp-(1-3)[α-L-Fucp-(1-2)]-β-D-Galp-(1-4)-β-D-GlcpNAc
2.35
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