Carbohydrate-Binding Module Family 4

Activities in FamilyModules of approx. 150 residues found in bacterial enzymes. Binding of these modules has been demonstrated with xylan, β-1,3-glucan, β-1,3-1,4-glucan, β-1,6-glucan and amorphous cellulose but not with crystalline cellulose.
3D Structure Statusβ-sandwich
NotePreviously known as cellulose-binding domain family IV (CBD IV).
External resourcesCAZypedia; HOMSTRAD;
Statistics GenBank accession (1463); Uniprot accession (41); PDB accession (19); 3D entries (11); cryst (4)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 N0X72_04060   Streptomyces carpaticus SCPM-O-B-9993 UWM52413.1    
 NRO40_00060   Streptomyces changanensis HL-66 UUS29386.1    
 CP983_03065   Streptomyces chartreusis ATCC 14922 QEV65767.1    
 HUT05_04515   Streptomyces chartreusis NA02069 QKZ16696.1    
 STRCI_007386   Streptomyces cinnabarinus DSM 40467 WAZ25860.1    
 Cel1 (SCO0765 or SCF81.24c)   Streptomyces coelicolor A3(2) CAB61539.1
NP_625068.1
   
 FQ762_03795   Streptomyces coelicolor A3(2) CFB_NBC_0001 QFI41016.1    
 JCM4020_07530   Streptomyces coelicolor JCM 4020 BDD70133.1    
 HCU77_03615   Streptomyces coelicolor M1154/pAMX4/pGP1416 QKN64688.1    
 RE436_03675   Streptomyces coelicolor M22 WMT31558.1    
 CP976_39135   Streptomyces coeruleorubidus ATCC 13740 QEV29533.1    
 PV963_41435   Streptomyces coeruleorubidus DM WDV56349.1    
 R5U08_39635   Streptomyces coeruleorubidus WT-48 WOT39856.1    
 RFN52_37275   Streptomyces collinus CGMCC 4.1623 WMX68686.1    
 QU709_00795   Streptomyces coralus SX92 WLW49979.1    
 EJ357_03245   Streptomyces cyaneochromogenes MK-45 AZQ32578.1    
 TU94_31425   Streptomyces cyaneogriseus subsp. noncyanogenus NMWT 1 AJP05267.1    
 D9753_34645   Streptomyces dangxiongensis Z022 AYN43177.1    
 BN159_1058 (Cel1)   Streptomyces davaonensis JCM 4913 CCK25437.1    
 L3078_41205   Streptomyces deccanensis KCTC 19241 ULR55187.1    
 NEH16_14070   Streptomyces drozdowiczii MDA8-470 UZK55111.1    
 PS783_33900   Streptomyces enissocaesilis NBF 715 WDI22300.1    
 IM697_20595   Streptomyces ferrugineus CCTCC AA2014009 QOV40586.1    
 IM697_18125   Streptomyces ferrugineus CCTCC AA2014009 QOV40145.1    
 F0344_09515   Streptomyces finlayi NBSH44 QNE74818.1    
 CP974_00260   Streptomyces fradiae ATCC 10745 = DSM 40063 QEV15404.1    
 RYQ63_13605   Streptomyces fradiae FIMYZ-003 WOI63736.1    
 CNQ36_02730   Streptomyces fungicidicus TXX3120 AYL34431.1    
 CP966_32720   Streptomyces galilaeus ATCC 14969 QEU69508.1    
 IAG43_28985   Streptomyces genisteinicus CRPJ-33 QNP67649.1    
 SGLAU_29995 (Cel1)   Streptomyces glaucescens GLA.O AIS01933.1    
 C0216_15270   Streptomyces globosus LZH-48 AXE24642.1    
 SGFS_101720   Streptomyces graminofaciens A-8890 BBC38878.1    
 V9K83_32860   Streptomyces griseoaurantiacus XQ-29 WWY88623.1    
 UBV09_31340   Streptomyces griseoincarnatus HNS054 WPW22901.1    
 DWG14_00943 (Cel1)   Streptomyces griseorubiginosus 3E-1 AYC36733.1    
 ELQ87_02905   Streptomyces griseoviridis F1-27 AZS83360.1    
 DDJ31_36455   Streptomyces griseoviridis K61 QCN89787.1    
 HUT13_03600   Streptomyces harbinensis NA02264 QKV71949.1    
 CEB94_37885   Streptomyces hawaiiensis ATCC 12236 QCD59918.1    
 RFN58_39980   Streptomyces iakyrus CGMCC 4.1912 WVG06893.1    
 RI060_02565   Streptomyces janthinus JCM 4387 WND16302.1    
 KJK29_01815   Streptomyces koelreuteriae MG62 QWB21407.1    
 Sle_05320   Streptomyces leeuwenhoekii C34 (= DSM 42122 = NRRL B-24963) CQR59994.1    
 GJU35_41215   Streptomyces lincolnensis B48 QMV11479.1    
 SLCG_7707   Streptomyces lincolnensis LC-G AXG58862.1    
 SLINC_7720   Streptomyces lincolnensis NRRL 2936 ANS69944.1    
 SLITK23_07180   Streptomyces lividans TK23 BDE37473.1    
 SLIV_34105 (Cel1)   Streptomyces lividans TK24 AIJ17704.1    
 LC193_19400   Streptomyces marincola SCSIO 64649 UCM91888.1    
 POD33_36700   Streptomyces moderatus DT446 WCH97377.1    
 CP967_04160   Streptomyces nitrosporeus ATCC 12769 QEU71256.1    
 CP978_05615   Streptomyces nodosus ATCC 14899 QEV38078.1    
 SNOD_05270   Streptomyces nodosus ATCC 14899 AJE39496.1    
 B1H29_03280   Streptomyces pactum ACT12 AQS71780.1    
 DVK44_09820   Streptomyces paludis GSSD-12 AXG77952.1    
 DVK44_07695   Streptomyces paludis GSSD-12 AXG77599.1    
 Spa2297_29885   Streptomyces parvulus 2297 ANJ10828.1    
 OHB35_46735   Streptomyces phaeochromogenes NBC 01752 WSD20140.1    
 OG931_47950   Streptomyces phaeochromogenes NBC_00186 WRZ34926.1    
 F9278_43320   Streptomyces phaeolivaceus GY16 QFR01885.1    
 NFX46_14305   Streptomyces phaeoluteigriseus Qhu-M197 USQ84863.1    
 CP972_32800   Streptomyces prasinus ATCC 13879 QEV09748.1    
 V3O62_31950   Streptomyces prasinus WY33 WVU02100.1    
 Sfla_0181   Streptomyces pratensis ATCC 33331 ADW01649.1    
 SPRI_0438   Streptomyces pristinaespiralis HCCB 10218 ALC18744.1    
 H3L99_34765   Streptomyces pristinaespiralis PR11 QMU18819.1    
 A4E84_37755   Streptomyces qaidamensis S10(2016) AMW14716.1    
 FQU76_00710   Streptomyces qinzhouensis SSL-25 QDY75259.1    
 TUE45_pSRTUE45c_0260 (Cel1)   Streptomyces reticuli CUW32892.1    
 endo-1,4-glucanase I (Cel1)   Streptomyces reticuli CAA46570.1 Q05156  
 TR631_33290   Streptomyces rochei D21E05 WQC16440.1    
 P7W03_32020   Streptomyces rochei JK1 WMC89952.1    
 RBH85_03515   Streptomyces rochei S32 WMI55963.1    
 IAG44_36885   Streptomyces roseirectus CRXT-G-22 QNP74488.1    
 A4G23_00036 (Cel1)   Streptomyces rubrolavendulae MJM4426 AOT57250.1    
 SCAB_8871 (Cel1)   Streptomyces scabiei 87.22 CBG68068.1    
 P8T65_04510   Streptomyces sp. 11x1 WNZ06932.1    
 SAMN05428941_0821   Streptomyces sp. 2114.2 SDS61771.1    
 SAMN05444521_0963   Streptomyces sp. 3214.6 SHH56905.1    
 ASR50_32430   Streptomyces sp. 4F ALV53662.1    
 K5X85_31850   Streptomyces sp. A144 UAX57289.1    
 IOD14_17225   Streptomyces sp. A2-16 QUC58414.1    
 N7U49_07555   Streptomyces sp. AD2-2 UXX92248.1    
 P8A21_22250   Streptomyces sp. Alt1 WLQ50030.1    
 P8A19_18440   Streptomyces sp. Alt2 WLQ57306.1    
 P8A20_00685   Streptomyces sp. Alt3 WLQ62190.1    
 PZB77_11290   Streptomyces sp. AM 2-1-1 WEH43675.1    
 CVT30_03540   Streptomyces sp. AMCC400023 UJV39060.1    
 RI578_03415   Streptomyces sp. BB1-1-1 WND33396.1    
 OH540_03450   Streptomyces sp. BPPL-273 WHM29125.1    
 QIY60_30325   Streptomyces sp. BPTC-684 WHM40748.1    
 JIX56_19085   Streptomyces sp. CA-210063 UUU31841.1    
 JIX56_02705   Streptomyces sp. CA-210063 UUU28897.1    
 N7925_02955   Streptomyces sp. CA-278952 WDG27367.1    
 C4J65_00075   Streptomyces sp. CB09001 AXL86888.1    
 NI25_02485   Streptomyces sp. CCM_MD2014 AIV32531.1    
 AS200_06230   Streptomyces sp. CdTB01 ALV31681.1    
 RJD14_32030   Streptomyces sp. CGMCC 4.1456 WNF66921.1    
 VJ737_02785   Streptomyces sp. CGMCC 4.1772 WRT96672.1    
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