Known Activities	Binding to galactose and lactose has been demonstrated for the module of Micromonospora viridifaciens sialidase (PMID: 16239725). Binding to polygalacturonic acid has been shown for a Yersinia member (PMID: 17292916). Binding to LacNAc (β-D-galactosyl-1,4-β-D-N-acetylglucosamine) has been shown for an N-acetylglucosaminidase from Clostridium perfingens (PMID: 16990278).
3D Structure Status	β-sandwich
Note	Formerly known as X56 modules. Distantly related to CBM6 modules and to Anguilla anguilla agglutinin.
External resources	InterPro; PFAM;
Statistics	GenBank accession (1127); Uniprot accession (641); PDB accession (46); 3D entries (16); cryst (1)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
BF3579		Bacteroides fragilis NCTC 9343	CAH09262.1	Q5L9G5	3F2Z[A]
BT0865		Bacteroides thetaiotaomicron VPI-5482	AAO75972.1 NP_809778.1		2KD7[A] 3GGL[A]
core 1 endo-α-N-acetylgalactosaminidase (EngBF;BLLJ_0168)		Bifidobacterium longum subsp. longum JCM 1217	AAX44931.1 BAJ65838.1 CAM83935.1	Q3T552	2ZXQ[A]
exo-β-N-acetylglucosaminidase (NagH;CPF_0184)		Clostridium perfringens ATCC 13124	ABG83307.1	Q0TUP2	2W1Q[A,B] 2W1S[A,B] 2W1U[A,B,C,D] 2WDB[A,B,C,D]
α-N-acetylglucosaminidase (CPF_0859)		Clostridium perfringens ATCC 13124	ABG84150.1	Q0TST1	2VC9[A] 2VCA[A] 2VCB[A] 2VCC[A]
hyaluronidase (NagJ;CPF_1442)		Clostridium perfringens ATCC 13124	ABG84519.1	Q0TR53	2J1A[A] 2J1E[A] 2J1F[A] 2V5D[A]
exo-α-sialidase (NanJ;CPE0553)		Clostridium perfringens str. 13	BAB80259.1 NP_561469.1	Q8XMY5	2V72[A]
β-N-acetylglucosaminidase (NagJ;CPE1234) (GH84C)		Clostridium perfringens str. 13	BAB80940.1 NP_562150.1	Q8XL08	2J7M[A]
sialidase (NedA)		Micromonospora viridifaciens	AAQ70871.1 BAA00852.1	Q02834	1EUT[A] 1EUU[A] 1W8N[A] 1W8O[A] 1WCQ[A,B,C] 2BER[A] 2BQ9[A,B,C] 2BZD[A,B,C]
endo-β-N-acetylglucosaminidase D (Endo-D)		Streptococcus pneumoniae	BAB62042.1	Q93HW0	2XQX[A,B]
Spr0440		Streptococcus pneumoniae R6	AAK99244.1 NP_358034.1	Q8CZ52	3GDB[A]
endo-α-N-acetylgalactosaminidase (spr0328) (SpGH101)		Streptococcus pneumoniae R6	AAK99132.1 CAM83936.1	Q8DR60	3ECQ[A,B]
core 1 endo-α-N-acetylgalactosaminidase (EngSP;SP_0368)		Streptococcus pneumoniae TIGR4	ABC75807.1		cryst
endo-β-N-acetylglucosaminidase D (EndoD;Endo-D;Sp0498;SP_0498)		Streptococcus pneumoniae TIGR4	AAK74656.1 NP_345016.1	Q97S90	2W91[A] 2W92[A]
polygalacturonic acid-binding protein		Yersinia enterocolitica ATCC 9610D			2JD9[A] 2JDA[A,B]
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
galactose oxidase (GaoA)		Gibberella zeae	AAO95371.1 AAO95372.1 AAO95373.1 AAO95374.1 AAW14679.1 AAW14680.1 ABJ31020.1 ABJ31021.1 ABJ31022.1 ABJ31023.1 ABJ31024.1 ABJ31025.1 ABJ31026.1 ABJ31027.1 ABJ31028.1 ABJ31029.1 ABJ31030.1 ABJ31031.1 ABJ43047.1 ABJ43048.1 ABJ43049.1 ABJ43050.1 ABJ43051.1 ABJ43052.1 ABJ43053.1 ABJ43054.1 ABJ43055.1 ABJ43056.1 ABJ43057.1 ABJ43058.1	Q01745	1GOF[A] 1GOG[A] 1GOH[A] 1K3I[A] 1T2X[A] 2EIB[A] 2EIC[A] 2EID[A] 2EIE[A] 2JKX[A] 2VZ1[A] 2VZ3[A] 2WQ8[A]

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