Carbohydrate-Binding Module Family 2

Activities in FamilyModules of approx. 100 residues and which are found in a large number of bacterial enzymes. The cellulose-binding function has been demonstrated in many cases. Several of these modules have been shown to also bind chitin or xylan.
3D Structure Statusβ-sandwich
NotePreviously known as cellulose-binding domain family II (CBD II).
External resourcesHOMSTRAD; PROSITE;
Statistics GenBank accession (3534); Uniprot accession (776); PDB accession (16); 3D entries (8); cryst (0)
All (3425) Archaea (17) Bacteria (3208) Eukaryota (146) Viruses (43) unclassified (11) Structure (8) Characterized (167)
Archaea
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 chitinase (PF1234+PF1233;ChiA+ChiB) (Chi18B+Chi18A) 3.2.1.14 Pyrococcus furiosus DSM 3638 AAL81357.1
NP_578962.1
Q8U1H5
2CWR[A] 1.70
2CZN[A] NMR
 chitinase A (ChiA;TK1765) 3.2.1.14
3.2.1.-
Thermococcus kodakarensis KOD1 BAD85954.1
CAT70561.1
Q9UWR7
5DHD[A] 1.27
 chitinase A (ChiA;TK1765) 3.2.1.14
3.2.1.-
Thermococcus kodakarensis KOD1 BAD85954.1
CAT70561.1
Q9UWR7
5DHE[A,B] 1.60
Bacteria
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 xylanase D / 11A (XynD;XylD;Xyl11A) (Xyn11A) 3.1.1.72
3.2.1.8
Cellulomonas fimi 221 CAA54145.1 P54865
1E5B[A] NMR
1E5C[A] NMR
1XBD[A] NMR
2XBD[A] NMR
 xylanase D / 11A (XynD;XylD;Xyl11A) (Xyn11A) 3.1.1.72
3.2.1.8
Cellulomonas fimi 221 CAA54145.1 P54865
1HEH[C] NMR
1HEJ[C] NMR
 xylanase B / 10A (Cex;Exg;XynB;Celf_1271) (Xyn10A) 3.2.1.8 Cellulomonas fimi ATCC 484 AEA30147.1
AAA56791.1
AAA56792.1
AAB34464.1
AEE45406.1
P07986
Q59277
1EXG[A] NMR
1EXH[A] NMR
 endo-β-1,4-glucanase / xylanase D (EngD) 3.2.1.4
3.2.1.73
3.2.1.8
Clostridium cellulovorans ATCC 35269 AAA23233.1 P28623
3ICG[A,B,C,D] 2.10
3NDY[E,F,G,H] 2.10
3NDZ[E,F,G,H] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp
2.08
 chitinase C (ChiC;Chi18aC;ScChiC;2SC6G5.20c;SCO5376) (Chi18C) 3.2.1.14 Streptomyces coelicolor A3(2) CAB94547.1
AAD16453.1
BAA75644.1
NP_629515.1
Q7AKG2
Q9Z9M8
2RTT[A] NMR
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