Activities in Family	Modules of approx. 100 residues and which are found in a large number of bacterial enzymes. The cellulose-binding function has been demonstrated in many cases. Several of these modules have been shown to also bind chitin or xylan.
3D Structure Status	β-sandwich
Note	Previously known as cellulose-binding domain family II (CBD II).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Statistics	GenBank accession (12864); Uniprot accession (198); PDB accession (19); 3D entries (10); cryst (0)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
glycosyl hydrolase family 6 domain-containing protein		Cellvibrionaceae bacterium Bs12	AIF91538.1
glycosyl hydrolase family GH5_53 domain-containing protein		Cellvibrionaceae bacterium Bs12	AIF91526.1
glycosyl hydrolase family 5_2 domain-containing protein		Cellvibrionaceae bacterium Bs12	AIF91536.1
glycosyl hydrolase family 45 domain-containing protein		Cellvibrionaceae bacterium Bs12	AIF91527.1
plant cell wall polysaccharide active protein		Cellvibrionaceae bacterium Bs12	AIF91530.1
plant cell wall polysaccharide active protein		Cellvibrionaceae bacterium Bs12	AIF91530.1
plant cell wall polysaccharide active protein		Cellvibrionaceae bacterium Bs12	AIF91525.1
glycosyl hydrolase family 5_53 domain-containing protein		Cellvibrionaceae bacterium Bs12	AIF91542.1
glycosyl hydrolase family 5_53 domain-containing protein		Cellvibrionaceae bacterium Bsc2	AIF91521.1
VSU16_10255		Cetobacterium somerae	WVJ02476.1
MKD34_12105		Cetobacterium somerae CS2105-BJ	UPO98370.1
Cagg_3435		Chloroflexus aggregans DSM 9485	ACL26277.1
NIES4102_25120		Chondrocystis sp. NIES-4102	BAZ45488.1
NIES4102_25120		Chondrocystis sp. NIES-4102	BAZ45488.1
NIES4102_27570		Chondrocystis sp. NIES-4102	BAZ45731.1
NIES4102_27570		Chondrocystis sp. NIES-4102	BAZ45731.1
NIES4102_37880		Chondrocystis sp. NIES-4102	BAZ46748.1
CMC5_029080		Chondromyces crocatus Cm c5	AKT38762.1
CMC5_079670		Chondromyces crocatus Cm c5	AKT43732.1
endoglucanase (CelB)		Clavibacter capsici 1101	QGL06814.1
GW570_11760		Clavibacter capsici 1101	QIS45712.1
endoglucanase (CelB)		Clavibacter capsici 1106	QGL06815.1
GW571_11790		Clavibacter capsici 1106	QIS42769.1
GW572_12210		Clavibacter capsici 1207	QIS39854.1
AES38_11775 (CelB)		Clavibacter capsici PF008	ALD13503.1
K0V08_15520		Clavibacter michiganensis LMG7333	UGY90189.1
BEH62_15190		Clavibacter michiganensis subsp. insidiosus ATCC 10253	AWG02938.1
VO01_15470		Clavibacter michiganensis subsp. insidiosus R1-1	AJW80648.1
VO01_11370		Clavibacter michiganensis subsp. insidiosus R1-1	AJW79649.1
BEH61_03535		Clavibacter michiganensis subsp. insidiosus R1-3	AWF97569.1
BEH61_15105		Clavibacter michiganensis subsp. insidiosus R1-3	AWF99834.1
DQP62_15665		Clavibacter michiganensis subsp. michiganensis A4758	UQZ32052.1
DQP53_04790		Clavibacter michiganensis subsp. michiganensis A5747*	UQZ78610.1
CelA		Clavibacter michiganensis subsp. michiganensis BT0505	AHN16207.1
LHJ48_12725 (fragment)		Clavibacter michiganensis subsp. michiganensis CMM09	UDM13254.1
LHJ48_15560		Clavibacter michiganensis subsp. michiganensis CMM09	UDM15345.1
LHJ47_15595		Clavibacter michiganensis subsp. michiganensis CMM39	UDM22033.1
PSI72_15530		Clavibacter michiganensis subsp. michiganensis CMM39	WDD26916.1
PSI72_12695 (fragment)		Clavibacter michiganensis subsp. michiganensis CMM39	WDD24831.1
LHJ49_12720 (fragment)		Clavibacter michiganensis subsp. michiganensis CMM84	UDM10135.1
LHJ49_15550		Clavibacter michiganensis subsp. michiganensis CMM84	UDM12234.1
PSS89_12690 (fragment)		Clavibacter michiganensis subsp. michiganensis Cmm_21	WDD27940.1
PSS89_15525		Clavibacter michiganensis subsp. michiganensis Cmm_21	WDD30030.1
GRD74_15765		Clavibacter michiganensis subsp. michiganensis MSF322	QIT13040.1
endo-1,4-β-glycosidase, partial (CelB) (fragment)		Clavibacter michiganensis subsp. michiganensis MSF322	QYU76393.1
MU580_12950		Clavibacter michiganensis subsp. michiganensis N.P.	UOW03165.1
CMM_2443 (CelB)		Clavibacter michiganensis subsp. michiganensis NCPPB 382	CAN02524.1
bifunctional cellulase / expansin (CelA;pCM1_0020)		Clavibacter michiganensis subsp. michiganensis NCPPB 382	CAA44467.2 CAM98473.1	A5CLK3 Q9K5C7
endo-1,4-β-glycosidase, partial (CelB) (fragment)		Clavibacter michiganensis subsp. michiganensis OP3	QYU76398.1
endo-1,4-β-glycosidase, partial (CelB) (fragment)		Clavibacter michiganensis subsp. michiganensis OP7	QYU76399.1
EFE39_15410		Clavibacter michiganensis subsp. michiganensis UF1	QGV76751.1
endo-1,4-β-glycosidase, partial (CelB) (fragment)		Clavibacter michiganensis subsp. michiganensis VL368	QYU76394.1
GRD61_16045		Clavibacter michiganensis subsp. michiganensis VL527	QIT16217.1
GRD61_12870		Clavibacter michiganensis subsp. michiganensis VL527	QIT15432.1
endo-1,4-β-glycosidase, partial (CelB) (fragment)		Clavibacter michiganensis subsp. michiganensis VL542	QYU76397.1
endo-1,4-β-glycosidase, partial (CelB) (fragment)		Clavibacter michiganensis subsp. michiganensis VQ143	QYU76392.1
KN200_15915		Clavibacter michiganensis subsp. michiganensis VQ28	QXP07556.1
endo-1,4-β-glycosidase, partial (CelB) (fragment)		Clavibacter michiganensis subsp. michiganensis VQ28	QYU76391.1
endo-1,4-β-glycosidase, partial (CelB) (fragment)		Clavibacter michiganensis subsp. michiganensis VQ519	QYU76395.1
WDV94_00710		Clavibacter michiganensis subsp. tessellarius ARGTr 8-1	WXZ50307.1
FGG90_08370		Clavibacter michiganensis subsp. tessellarius ATCC 33566	UKF34016.1
LIX20_002396		Clavibacter nebraskensis 419B	UQB13027.1
LIX22_002395		Clavibacter nebraskensis 44	UQB15862.1
EGX35_11885		Clavibacter nebraskensis 61-1	QGV73059.1
EGX37_11885		Clavibacter nebraskensis 7580	QGV70268.1
FGQ65_12460		Clavibacter nebraskensis A6096	UKF28935.1
LIX19_002386		Clavibacter nebraskensis CIBA	UQB10191.1
LIV34_002383		Clavibacter nebraskensis CNK-2	UQB04538.1
EGX36_11930		Clavibacter nebraskensis HF4	QGV67468.1
CMN_00144		Clavibacter nebraskensis NCPPB 2581	CCE74122.1
CMN_02390 (CeL)		Clavibacter nebraskensis NCPPB 2581	CCE76326.1
LIX21_002384		Clavibacter nebraskensis SL1	UQB09295.1
cellulase (CelA;pCS0061)		Clavibacter sepedonicus ATCC 33113	AAK16222.1 CAQ03244.1	B0RJ54 Q9AF65
LRE50_16125		Clavibacter sepedonicus K496	UUK67285.1
LRE50_00240		Clavibacter sepedonicus K496	UUK67197.1
KYT88_12615		Clavibacter sp. A6099	UKF24556.1
PV797_16260		Clostridiaceae bacterium M8S5	WDV45062.1
PV797_16695		Clostridiaceae bacterium M8S5	WDV45142.1
PV797_16100		Clostridiaceae bacterium M8S5	WDV45031.1
PV797_16100		Clostridiaceae bacterium M8S5	WDV45031.1
CLAUR_046190		Clostridium aurantibutyricum DSM 793	URZ04530.1
CCDG5_0326		[Clostridium] cellulosi	CDZ23468.1
CCDG5_0326		[Clostridium] cellulosi	CDZ23468.1
Clocel_3242		Clostridium cellulovorans 743B	ADL52928.1
endo-β-1,4-glucanase / xylanase D (EngD)		Clostridium cellulovorans ATCC 35269	AAA23233.1	P28623	3ICG[A,B,C,D] 3NDY[E,F,G,H] 3NDZ[E,F,G,H]
LL033_14590		Clostridium estertheticum CF002	WAG57973.1
LL065_04285		Clostridium estertheticum CF016	WAG43399.1
A7L45_18475		Clostridium estertheticum subsp. estertheticum DSM 8809	APC41907.1
CLFE_048450		Clostridium felsineum DSM 794	URZ18757.1
J1C67_10265		Clostridium gasigenes CGAS001	QSW17965.1
J1C67_18125		Clostridium gasigenes CGAS001	QSW19421.1
endo-β-1,4-glucanase (CelA)		Clostridium longisporum	AAC37035.1	P54937
CNEO_1651		Clostridium neonatale	CAH0436308.1
CNEO_1651		Clostridium neonatale	CAH0436308.1
CLROS_047320		Clostridium roseum DSM 6424	URZ09316.1
CROST_047800		Clostridium roseum DSM 7320	URZ14002.1
CSACC_09830 (Cel5A)		Clostridium saccharobutylicum BAS/B3/SW/136	AQR99180.1
CLSA_c09900 (EglA)		Clostridium saccharobutylicum DSM 13864	AGX42001.1
CLOSACC_09830 (Cel5A)		Clostridium saccharobutylicum NCP 195	AQS13168.1
CLOSC_09760 (Cel5A)		Clostridium saccharobutylicum NCP 200	AQR89279.1
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