Carbohydrate-Binding Module Family 1

Activities in FamilyModules of approx. 40 residues found almost exclusively in fungi. The cellulose-binding function has been demonstrated in many cases, and appears to be mediated by three aromatic residues separated by about 10.4 angstrom and which form a flat surface. The only non-fungal occurence of CBM1 is in an algal non-hydrolytic polysaccharide-binding protein which is composed of four repeated CBM1 modules. Binding to chitin has been demonstrated in one case.
NotePreviously known as cellulose-binding domain family I (CBD I).
External resourcesPROSITE; SMART;
Statistics GenBank accession (1213); Uniprot accession (331); PDB accession (20); 3D entries (5); cryst (1)
All (1046) Bacteria (1) Eukaryota (1039) Viruses (1) unclassified (5) Structure (5 - 1 cryst) Characterized (217)
Eukaryota
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 cellobiose dehydrogenase IIA (Cdh;MtCDH) 1.1.99.18 Crassicarpon hotsonii ABS45567.2
ABS45566.1
A9XK87
A9XK88
4QI4[A] 2.70
4QI5[A] β-D-Glcp-(1-1)-<non_carb>
2.40
4QI6[A] 3.20
 cellobiose dehydrogenase IIA (Cdh-1;CDH-1;CdhIIA;Nc-Cdh1;NCU00206) 1.1.99.18 Neurospora crassa OR74A EAA27355.1
XP_322292.1
 
4QI7[A,B] 2.90
 feruloyl esterase B (FaeB;TcFAE)   Talaromyces cellulolyticus CF-2612 BAP90855.1  
cryst    
 cellobiohydrolase I / chitosanase (CBHI;Cbh1;CBH-I;TrCel7A;HjCel7A;TreCel7A) (Cel7A) 3.2.1.176
3.2.1.132
Trichoderma reesei CAH10320.1
CAF32518.1
CAR96030.1
P62694
1AZ6[A] NMR
1AZH[A] NMR
1AZJ[A] NMR
1AZK[A] NMR
1CBH[A] NMR
2CBH[A] NMR
2MWJ[A] NMR
2MWK[A] NMR
5X34[A] NMR
5X35[A] NMR
5X36[A] NMR
5X37[A] NMR
5X38[A] NMR
5X39[A] NMR
5X3C[A] NMR
 endo-β-1,4-glucanase I (EGI;Egl1;EG-I;TrCel7B) (Cel7B) 3.2.1.4 Trichoderma reesei AAA34212.1
ABE22091.1
CAR96034.1
P07981
4BMF[A] NMR
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