Activities in Family	Peroxidases (EC 1.11.1.-); Ascorbate peroxidase (EC 1.11.1.11); Manganese peroxidase (EC 1.11.1.13); Lignin peroxidase (EC 1.11.1.14); Versatile peroxidase (EC 1.11.1.16); Cytochrome-c peroxidase (EC 1.11.1.5);
Note	Family AA2 contains class II lignin-modifying peroxidases. AA2 enzymes are secreted heme-containing enzymes that use hydrogen peroxide or organic peroxides as electron acceptors to catalyze a number of oxidative reactions in which two electrons are derived from substrate molecules to reduce the enzyme followed by a concomitant release of two water molecules.
Statistics	GenBank accession (1246); Uniprot accession (35); PDB accession (77); 3D entries (21); cryst (0)

Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Resolution (Å)
peroxidase (ArP)		Agaricales sp. Arthromyces ramosus	BAA09861.1	P28313	1ARP[A] 1.90 1ARU[A] 1.60 1ARV[A] 1.60 1ARW[A] 1.60 1ARX[A] 1.90 1ARY[A] 1.90 1C8I[A] 2.00 1CK6[A] 1.90 1GZA[A] 2.06 1GZB[A] 1.80 1HSR[A] 1.60
lignin peroxidase (CPC08DRAFT_705809)		Agrocybe pediades AH 40210	KAF9563666.1	A0A8X6EH08	7OO5[A] 1.85
lignin peroxidase (D9613_004605)		Agrocybe pediades CBS 102.39	KAF4612378.1	A0A8H4QK56	8QWX[A] 1.60 8QX0[A] 1.25
peroxidase (Cip1)		Coprinopsis cinerea IFO 8371	CAA49216.1		1H3J[A,B] 2.0 1LY8[A,B] 2.05 1LY9[A,B] 2.00 1LYC[A,B] 1.57 1LYK[A,B] 2.00
lignin peroxidase (BDQ17DRAFT_1413095;Mnpaa5)		Cyathus striatus AH 40144	KAF8993196.1		8QWT[A] 1.50
manganese peroxidase (MnP6;CERSUDRAFT_50686)		Gelatoporia subvermispora	EMD37281.1	M2REM6	4CZN[A] 1.20 4CZO[A] 1.20 4CZP[A] 1.90 4CZQ[A] 1.20 4CZR[A] 1.98
ascorbate peroxidase 1, cytosolic (Apx1)		Glycine max	NP_001237785.1	Q43758	6TAE[A] 1.90 6XV4[A] 1.90 7BI1[A] 1.50 7S10[A] 1.40
ascorbate peroxidase (PVAP13_9KG480900)		Panicum virgatum AP13	KAG2552739.1	A0A8T0NWI5	8FF6[A,B,C,D,E,F] 2.49 8FF7[A,B,C,D,E,F] 2.19
lignin peroxidase LiP2		Phanerochaete chrysosporium	AAA33735.1		1LGA[A,B] 2.03 1LLP[A] 1.70
manganese peroxidase I (MnP1)		Phanerochaete chrysosporium	AAA33742.1 AAA33743.1	Q02567	1MN1[A] 2.00 1MN2[A] 2.00
ligninase isozyme H8		Phanerochaete chrysosporium	AAA53109.1		1B80[A,B] 1.73 1B85[A,B] 1.85
RecName: Full=Ligninase H8; AltName: Full=Diarylpropane peroxidase; AltName: Full=Lignin peroxidase; Flags: Precursor. (LpoA)		Phanerochaete chrysosporium	P06181.1		6A6Q[A] 1.67
ligninase		Phanerochaete chrysosporium BKM1767	CAA68373.1		1B82[A,B] 1.80
lignin peroxidase H1/H2 (Lip2)		Phanerochaete chrysosporium BKMF 1767, ATCC 24725	CAA33621.1 AAA33733.1	P11542	1QPA[A,B] 1.80
altern. mat. ligninase, alternative (fragment)		Phanerochaete chrysosporium SC26, NRRL 15978	CAB37300.1		6ISS[A,G] 1.53
versatile peroxidase (Vpl;VPL2)		Pleurotus eryngii ATCC 90787; CBS 613.91; IJFM A169	AAD01402.1	O94753	2BOQ[A] 1.33 4FCN[A] 1.70 4FCS[A] 1.50 4FDQ[A] 1.60 4FEF[A] 2.00 4G05[A] 2.35 5ABN[A] 2.19 5ABO[A] 1.10 5ABQ[A] 2.29 5FNB[A,B] 1.79 5FNE[A] 1.50
versatile peroxidase I (VpI;116738) (partial)		Pleurotus ostreatus PC9			4BLL[A] 1.10 4BLN[A] 1.15 4BLX[A] 1.25 4BLY[A] 1.79 4BLZ[A,B] 2.00 4BM0[A] 2.20 4BLK[A] 1.05
manganase peroxidase 4 (MnP4;121638)		Pleurotus ostreatus PC9		W5IDB6	4BM1[B] 1.10 4BM2[A] 1.39 4BM3[A] 1.65 4BM4[A] 2.30 4BM1[A] 1.10
cytochrome-c peroxidase (PACBIOSEQ_LOCUS3726)		Saccharomyces cerevisiae HN1	CAD6634053.1	A0A7I9FEW7 P00431	7BIU[A] 1.06
YKR066C (Ccp1)		Saccharomyces cerevisiae S288C	NP_012992.1	P00431	6H08[A,B,C] 1.90 6P41[A,C] 2.90 6P42[A,C] 2.91 6P43[A,C] 1.91 6Y1T[A] 1.50 6Y2Y[A] 1.70
L-ascorbate peroxidase 1, cytosolic (Loc8081447)		Sorghum bicolor	XP_002468053.1	A0A921S579 C5WNL8	8DJR[A] 1.46 8DJS[A] 1.19 8DJT[A] 1.16 8DJU[A] 1.50 8DJW[A] 1.80 8DJX[A] 1.34
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