Auxiliary Activity Family 1

Activities in FamilyLaccase / p-diphenol:oxygen oxidoreductase / ferroxidase (EC 1.10.3.2); ; ferroxidase (EC 1.10.3.-); Laccase-like multicopper oxidase (EC 1.10.3.-)
NoteThe characterized AA1 enzymes are multicopper oxidases that use diphenols and related substances as donors with oxygen as the acceptor. The AA1 family is currently divided into 3 subfamilies including laccases, ferroxidases and laccase-like multicopper oxidases.
Statistics GenBank accession (6141); Uniprot accession (79); PDB accession (89); 3D entries (25); cryst (0)
Eukaryota
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D Subf
 laccase (McoG;An08g08450) 1.10.3.2   Aspergillus niger CBS 513.88 CAK40046.1 A2QS62 5LM8[A]
5LWW[A]
5LWX[A]
3
 dihydrogeodin oxidase (DhgO) 1.10.3.-   Aspergillus terreus IMI16043 BAA08486.1 Q00292   3
 laccase 1.10.3.2   basidiomycete PM1 PM1(CECT 2971) CAA78144.1 Q12571 5ANH[A,B,C] 1
 laccase (Lac;BaLac) 1.10.3.2   Botrytis aclada DSMZ 62081 AFC76164.1 H8ZRU2 3SQR[A]
3V9E[A]
4X4K[A]
3
 laccase 2 (Lac2) 1.10.3.2   Ceriporiopsis rivulosa T241i AFI57925.1 I1W1V8   1
 laccase 1 (Lac1) 1.10.3.2   Ceriporiopsis rivulosa T241i AFI57924.1 I1W1V7   1
 laccase 1 (Lac1) 1.10.3.2   Cerrena sp. HYB07 AGK89726.1 R4JRR8   1
 laccase 7 (LacA) 1.10.3.2   Cerrena sp. HYB07 AID59415.1 A0A0A0Q5C7   1
 laccase 3 (Lcc3) 1.10.3.2   Coprinopsis cinerea A3387 AAD30966.1 Q9Y782   1
 laccase 1 (Lcc1) 1.10.3.2   Coprinopsis cinerea A3387 AAD30964.1 Q9Y780 1A65[A]
1HFU[A]
1
 laccase 2 (Lcc2) 1.10.3.2   Coprinopsis cinerea okayama7#130 DAA04507.1 Q08AC5   1
 laccase 14 (Lcc14) 1.10.3.2   Coprinopsis cinerea okayama7#130 DAA04519.1 Q08AB3   1
 laccase 13 (Lcc13) 1.10.3.2   Coprinopsis cinerea okayama7#130 DAA04518.1 Q08AB4   1
 laccase 1 (Lcc1) 1.10.3.2   Coprinopsis cinerea okayama7#130 DAA04506.1 Q08AC6   1
 laccase 4 (Lcc4) 1.10.3.2   Coprinopsis cinerea okayama7#130 DAA04509.1 Q08AC3   1
 laccase 11 (Lcc11) 1.10.3.2   Coprinopsis cinerea okayama7#130 DAA04516.1 Q08AB6   1
 laccase 7 (Lcc7) 1.10.3.2   Coprinopsis cinerea okayama7#130 DAA04512.1 Q08AC0   1
 laccase 6 (Lcc6) 1.10.3.2   Coprinopsis cinerea okayama7#130 DAA04511.1 Q08AC1   1
 laccase 5 (Lcc5) 1.10.3.2   Coprinopsis cinerea okayama7#130 DAA04510.1 Q08AC2   1
 benzenediol:oxygen oxidoreductase / laccase (Lac3) 1.10.3.2   Coprinus comatus CDJ79884.1 X5JA14   1
 benzenediol:oxygen oxidoreductase / laccase (Lac4) 1.10.3.2   Coprinus comatus CDJ79885.1 X5JAK9   1
 laccase (Lac1) 1.10.3.2   Coriolopsis gallica SAH-12 ABD93940.1
ABD93941.1
Q1W6B1 4A2D[A]
4A2E[A]
4A2F[A]
4A2G[A]
4A2H[A]
5A7E[A]
1
 laccase (Lac) 1.10.3.2   Cyathus bulleri ABW75771.2 A8W7J6   1
 laccase (Lcc1) 1.10.3.2   Fusarium oxysporum 4287 ABS19938.1 A7LBK4   3
 laccase (Lcc3) 1.10.3.2   Fusarium oxysporum 4287 ABS19943.1 A7LBK9   2
 laccase (Lcc5) 1.10.3.2   Fusarium oxysporum 4287 ABS19941.1 A7LBK7  
 laccase (GlLac1) 1.10.3.2   Ganoderma lucidum 7071-9 AAG17009.2
ACN38062.1
Q9HG17   1
 laccase (Lcc1;Glac15) 1.10.3.2   Ganoderma lucidum CGMCC5.0026 AHA83584.1 V9PQZ7   1
 laccase 1.10.3.2   Ganoderma lucidum TR6 ACR24357.1 C5HL41   1
 laccase (Lcs1;Lcs-1) 1.10.3.2   Gelatoporia subvermispora AAO25685.1
AAC97074.2
AAO26040.1
O59944   1
 A0H81_06219 (Lcc1) 1.10.3.2   Grifola frondosa 9006-11 OBZ73752.1 A0A1C7MAA7   1
 laccase 1A (Lcc1A) 1.10.3.2   Lentinula edodes L54 AET86511.1 G9I8W6   1
 laccase 1B (Lcc1B) 1.10.3.2   Lentinula edodes L54 AET86512.1 G9I8W7   1
 laccase 4 allele A (Lcc4A) 1.10.3.2   Lentinula edodes L54-A AGO04559.1 R9WT55   1
 laccase 5 (Lcc5) 1.10.3.2   Lentinula edodes L54-A AGO04561.1 R9WU11   1
 laccase 7 (Lcc7) 1.10.3.2   Lentinula edodes L54-A AGO04562.1 R9WS76   1
 laccase (Lcc3;Lcc-3) 1.10.3.2   Lentinus sp. WR2 ACZ82339.1 I3NL60   1
 laccase (Lcc4) 1.10.3.2   Lentinus sp. WR2 AIT51846.1 A0A0F6NTZ1 3X1B[A,B] 1
 laccase (Lac1) 1.10.3.2   Melanocarpus albomyces CAE00180.1 Q70KY3 1GW0[A,B]
2IH8[A,B]
2IH9[A,B]
2Q9O[A,B]
3DKH[A,B]
3FU7[A,B]
3FU8[A,B]
3FU9[A,B]
3
 laccase I (Lacc1) 1.10.3.2   Neohortaea acidophila CBS 113389 AAY33970.1 Q50H78   3
 laccase II (Lacc2) (fragment) 1.10.3.2   Neohortaea acidophila CBS 113389 AAY33971.2 Q50H77   3
 laccase (Lac1) 1.10.3.2   Phoma sp. UHH 5-1-03 (DSM 22425) ABY89704.1
ABY89705.1
B3TLA6   3
 laccase (Pel3) 1.10.3.2   Pleurotus eryngii CBS 613.91 AAV85769.1 Q5MP11   1
 laccase / diphenol oxidase (Pox2) 1.10.3.2   Pleurotus ostreatus NRRL0366 CAA88895.1
BAH03528.1
CAA84357.1
B7XGB7
Q12739
  1
 laccase (Lac1) 1.10.3.2   Pleurotus sapidus DSMZ 8266 CAH05069.1 Q6A1A1   1
 laccase2 (Lac2) 1.10.3.2   Pleurotus sapidus DSMZ 8266 CAJ00406.1 Q4VY49   1
 laccase (PoxA1b) 1.10.3.2   Pleurotus sp. Florida CAA06291.1
CAA06292.1
O60199   1
 laccase (Lac1;PbLAC1 1.10.3.2   Polyporus brumalis KFRI 20912 / ibrc05015 ABN13591.1
BAM63494.1
A3F8Z8   1
 laccase 6 (Lac6;RfLacA) 1.10.3.2   Reticulitermes flavipes ACX54558.1 D0E8H0  
 laccase 12 (Lac12;RfLacB) 1.10.3.2   Reticulitermes flavipes ACX54560.1 D0E8H2  
 laccase (LcC) 1.10.3.2   Rigidoporus microporus AAO38869.1 Q6YA64   1
 laccase 1.10.3.2 pubmed
Rigidoporus microporus CAE81289.1 Q6H9H7 1V10[A] 1
 laccase 2 1.10.3.2   Steccherinum murashkinskyi AFI41889.1 I1VE66 5E9N[A]
5MEJ[A]
5MEW[A]
5MHU[A]
5MHV[A]
5MHW[A]
5MHX[A]
5MHY[A]
5MHZ[A]
5MI1[A]
5MI2[A]
5MIA[A]
5MIB[A]
5MIC[A]
5MID[A]
5MIE[A]
5MIG[A]
6RGH[A]
6RGP[A]
6RHH[A]
6RHI[A]
6RHO[A]
6RHP[A]
6RHR[A]
6RHU[A]
6RHX[A]
6RI0[A]
6RI2[A]
6RI4[A]
6RI6[A]
6RI8[A]
6RII[A]
6RIK[A]
6RIL[A]
1
 laccase 1.10.3.2   Thanatephorus cucumeris RS22 CAA91042.1
Q02081.1
Q02081   1
 laccase (Lcc1; MYCTH_51627) 1.10.3.2 pubmed
Thermothelomyces thermophilus ATCC 42464 XP_003663741.1 G2QG31 6F5K[A] 3
 laccase (Lcc1;TaLcc1) 1.10.3.2   Thielavia arenaria 333361328 F6N9E7 3PPS[A,B,C,D] 3
 laccase (Lcc3-2) 1.10.3.2   Trametes cinnabarina PB AAD49218.1 Q9UVU8   1
 laccase 1.10.3.2   Trametes coccinea BRFM 938 ACZ37082.1 D7F484   1
 laccase 1.10.3.2   Trametes coccinea IUM 0450 AKE14489.1 A0A0F6QMX4   1
 laccase (Lcc1) 1.10.3.2   Trametes coccinea M85-2 BAB69775.1
BAB69776.1
Q96TR6
Q96VA5
5NQ8[A] 1
 laccase / ligninolytic phenoloxidase 1.10.3.2   Trametes hirsuta IFO 4917 AAA33104.1
AAA33103.1
Q02497   1
 laccase 2 (Lap2) 1.10.3.2   Trametes pubescens AAM18407.1 Q8TG94   1
 laccase 1A (Lap1A) 1.10.3.2   Trametes pubescens AAM18408.1 Q8TG93   1
 laccase 1.10.3.2   Trametes sanguinea ACO51010.1 C1JCL7   1
 laccase 1.10.3.2   Trametes sanguinea BRFM 902 ACZ37083.1 D7F485 5NQ7[A] 1
 multicopper redoxase (Lcc1) 1.10.3.2   Trametes sanguinea H275 ACN69056.1
ACZ37081.1
C9WKP8   1
 laccase A (LacA) 1.10.3.2   Trametes sp. AH28-2 AAW28933.1 Q5MBH6   1
 laccase 2 (Lac2) 1.10.3.2   Trametes sp. C30 AAM66348.1
AAM66349.1
Q8NID5   1
 laccase / polyphenoloxidase (Lac1) 1.10.3.2   Trametes sp. C30 / Marasmius quercophilus C30 AAF06967.1
AAM10738.1
Q9UVQ5   1
 laccase 4 (Lac4;LccC) 1.10.3.2   Trametes versicolor BAD98308.1 Q50JG3   1
 laccase 3 (Lac3;LccB) 1.10.3.2   Trametes versicolor BAD98307.1 Q50JG4   1
 laccase I (LccI;Lcc2) 1.10.3.2   Trametes versicolor 52J AAA86659.1
AAC49828.1
Q12718 1GYC[A] 1
 laccase B (Lac1) 1.10.3.2   Trametes versicolor ATCC 32745 AAL07440.1 Q96UT7 1KYA[A,B,C,D] 1
 laccase II (Lcc1) 1.10.3.2   Trametes villosa CBS 678.70 AAC41686.1 Q99044   1
 laccase I (Lcc2) 1.10.3.2   Trametes villosa CBS 678.70 AAC41687.1 Q99046   1
 laccase 1 (Lac1) 1.10.3.2   Volvariella volvacea AAO72981.2 Q6X938   1
 unknown (fragment) 1.10.3.2   Zea mays B73 ACF79418.1 B4FBC5 6KLG[A]
6KLI[A]
6KLJ[A]
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