Glycoside Hydrolase Family 5 / Subf 17

Activities in Sub Family	Endo-β-1,4-mannanase (EC 3.2.1.78);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) ₈ barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (17); Uniprot accession (6);


Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
CAC0918		Clostridium acetobutylicum ATCC 824	AAK78894.1 NP_347554.1			17
SMB_G0935		Clostridium acetobutylicum DSM 1731	AEI31500.1			17
CEA_G0930		Clostridium acetobutylicum EA 2018	ADZ19969.1			17
DK921_10990		Clostridium acetobutylicum LJ4	AWV80613.1			17
CLAUR_014330		Clostridium aurantibutyricum DSM 793	URZ01438.1			17
β-mannanase A (ManA;Clocel_2818)	3.2.1.78	Clostridium cellulovorans 743B	AAF06110.2 ADL52514.1	C5RQ36 D9SS67 Q9LAJ3		17
CLFE_015510		Clostridium felsineum DSM 794	URZ15511.1			17
CLROS_010440		Clostridium roseum DSM 6424	URZ05718.1			17
CROST_014670		Clostridium roseum DSM 7320	URZ10757.1			17
Clo1100_1826		Clostridium sp. BNL1100	AEY66036.1			17
mannanase K (Man5K;Ccel_0736) (Man5K)	3.2.1.78	Ruminiclostridium cellulolyticum H10	ACL75115.1 AAG45159.1	B8I7V8 Q9EYQ3		17
mannanase 5A (Man5A)	3.2.1.78	Ruminiclostridium josui	BAI52931.1	D1MXA0		17
CpapDRAFT_3432		Ruminiclostridium papyrosolvens DSM 2782	EEU57771.1			17
P0092_10480		Ruminiclostridium papyrosolvens DSM 2782	WES36369.1			17
Top