CAZy ~ Carbohydrate-Active enZymes


   
Glycoside Hydrolase Family 8
  
Known Activitieschitosanase (EC 3.2.1.132); cellulase (EC 3.2.1.4); licheninase (EC 3.2.1.73); endo-1,4--xylanase (EC 3.2.1.8); reducing-end-xylose releasing exo-oligoxylanase (EC 3.2.1.156)
 
MechanismInverting
 
Catalytic Nucleophile/BaseAsp (inferred)
 
Catalytic Proton DonorGlu (experimental)
 
3D Structure StatusFold: ( / ) 6
 
ClanGH-M
 
Noteformerly known as cellulase family D
 
Relevant LinksInterPro   PFAM   PRINTS   PROSITE   
 
StatisticsCAZy Entries (219);  GenBank/GenPept (270);  Swissprot (34);  3D(6) : PDB(23);
 
TaxonomyBacteria(214);  unclassified(5);  
 
3D DisplayGH8_3D
 
        
        Bacteria          
ProteinEC#OrganismGenBank/GenPeptUniProtPDB/3D
Acry_0570 n.d.Acidiphilium cryptum JF-5CP000697
ABQ29794.1
   
endo-1,4-glucanase-like (CelC) (fragment) n.d.Agrobacterium tumefaciensL38609
AAC41433.1
Q44416
  
Atu3307 (CelC) n.d.Agrobacterium tumefaciens str. C58AE009260
NC_003305
AAL44120.1
NP_533804.1
   
AGR_L_3023glp n.d.Agrobacterium tumefaciens str. C58 (Cereon)AE008352
NC_003063
AAK90085.1
NP_357300.1
   
Adeh_2031 n.d.Anaeromyxobacter dehalogenans 2CP-CCP000251
ABC81801.1
   
Anae109_1778 n.d.Anaeromyxobacter sp. Fw109-5CP000769
ABS25981.1
   
endoglucanase (CelY;Aq_1401) - Cel8Y3.2.1.4
Aquifex aeolicus VF5AE000738
NC_000918
AAC07361.1
NP_213966.1
O67401
  
endo--1,4-glucanase (CmC) n.d.Asaia bogorensisAB355706
BAF75933.1
   
BA_3190 n.d.Bacillus anthracis str. A2012NC_003995
NP_656550.1
   
BA2673 n.d.Bacillus anthracis str. AmesAE017032
NC_003997
AAP26518.1
NP_845032.1
Q81PW9
  
GBAA2673 n.d.Bacillus anthracis str. Ames 0581AE017334
AAT31789.1
   
BAS2490 n.d.Bacillus anthracis str. SterneAE017225
AAT54801.1
   
BCE2710 (fragment) n.d.Bacillus cereus ATCC 10987AE017272
NC_003909
AAS41623.1
NP_979015.1
   
chitosanase (BC2682) 3.2.1.132
Bacillus cereus ATCC 14579AE017006
NC_004722
AAP09638.1
NP_832437.1
Q81CR5
  
chitosanase (fragment) 3.2.1.132
Bacillus cereus D-11     
pE33L466_0086 n.d.Bacillus cereus E33LCP000040
AAY60251.1
   
chitosanase (ChoA) 3.2.1.132
Bacillus cereus H-1AY207001
AAO49750.1
Q849S1
  
chitosanase (Csn) n.d.Bacillus cereus KNUC51AY296809
AAQ19678.1
   
chitosanase (Csn) n.d.Bacillus cereus KNUC52AY296811
AAQ19679.1
   
chitosanase (Csn) n.d.Bacillus cereus KNUC53AY304578
AAQ75084.1
   
chitosanase (Csn) n.d.Bacillus cereus KNUC54AY304579
AAQ75085.1
   
chitosanase (Csn) n.d.Bacillus cereus KNUC55AY304580
AAQ75086.1
   
BTZK2421 (ChoA) n.d.Bacillus cereus ZKCP000001
AAU17839.1
   
BglBC2 n.d.Bacillus circulans ATCC 21367AY269256
AAP22946.1
Q83ZQ6
  
endoglucanase N257 (Egl257) 3.2.1.4
Bacillus circulans KSM N257AB059267
BAB69035.1
Q93HV0
  
chitosanase/lichenase (Bgc) 3.2.1.132

3.2.1.73		Bacillus circulans WL-12X52880
CAA37062.1
P19254
  
reducing-end-xylose releasing exo-oligoxylanase (Rex;BH2105) 3.2.1.156
Bacillus halodurans C-125AP001514
NC_002570
BAB05824.1
NP_242971.1
Q9KB30
1WU4
1WU5
1WU6
2DRO
2DRQ
2DRR
2DRS
[A]
[A]
[A]
[A]
[A]
[A]
[A]
xylanase Y (fragment) n.d.Bacillus halodurans MIR32AY137373
AAN16076.1
Q8GLI2
  
chitosanase (ChoK) 3.2.1.132
Bacillus sp. K17   1V5C
1V5D
[A]
[A]
chitosanase (Csn45) n.d.Bacillus sp. KCTC 0377BPAF334682
AAK07481.1
Q9ALZ1
  
xylanase Y (XylY) 3.2.1.8
Bacillus sp. KK-1AF045480
AAC27700.1
O52730
  
endo-1,4-glucanase 3.2.1.4
Bacillus sp. KSM-330M68872
AAA22409.1
P29019
  
chitosanase 3.2.1.132
Bacillus sp. No.7-MAB051575
BAB19277.1
Q9F1P1
  
chitosanase 3.2.1.132
Bacillus sp. S65     
chitosanase (BTC11) 3.2.1.132
Bacillus thuringiensis serovar alestiEF143917
ABO61887.1
   
chitosanase (BTC19) 3.2.1.132
Bacillus thuringiensis serovar canadensisEF143924
ABO61894.1
   
chitosanase (BTC36) 3.2.1.132
Bacillus thuringiensis serovar darmstadiensisEF143921
ABO61891.1
   
chitosanase (BTC42) 3.2.1.132
Bacillus thuringiensis serovar israelensisEF143922
ABO61892.1
   
chitosanase (BTC30) 3.2.1.132
Bacillus thuringiensis serovar morrisoniEF143920
ABO61890.1
   
chitosanase (BTC31) 3.2.1.132
Bacillus thuringiensis serovar san diegoEF143918
ABO61888.1
   
chitosanase (BTC13) 3.2.1.132
Bacillus thuringiensis serovar sottoEF143923
ABO61893.1
   
chitosanase (BTC40) 3.2.1.132
Bacillus thuringiensis serovar thompsoniEF143919
ABO61889.1
   
chitosanase (BTC50) 3.2.1.132
Bacillus thuringiensis serovar tochigiensisEF143925
ABO61895.1
   
reducing end xylose-releasing exo-oligoxylanase (RexA;BAD_0300) 3.2.1.156
Bifidobacterium adolescentis ATCC 15703AP009256
BAF39081.1
   
reducing end xylose-releasing exo-oligoxylanase (RexA;XylA) 3.2.1.156
Bifidobacterium adolescentis DSM 20083AY233379
AAO67498.1
   
BAV2628 (BcsZ) n.d.Bordetella avium 197NAM167904
CAJ50238.1
   
BamMC406_1292 n.d.Burkholderia ambifaria MC40-6CP001025.1
ACB63782.1
   
Bcen_0898 n.d.Burkholderia cenocepacia AU 1054CP000378
ABF75807.1
   
Bcen2424_1380 n.d.Burkholderia cenocepacia HI2424CP000458
ABK08132.1
   
Bcenmc03_1358 n.d.Burkholderia cenocepacia MC0-3CP000958
ACA90533.1
   
Bamb_1259 n.d.Burkholderia cepacia AMMDCP000440
ABI86817.1
   
BMAA1589 (BcsC) n.d.Burkholderia mallei ATCC 23344CP000011
AAU45773.1
   
BMA10299_2008 n.d.Burkholderia mallei NCTC 10229CP000545
ABM99345.1
   
BMA10247_A0686 n.d.Burkholderia mallei NCTC 10247CP000547
ABO02081.1
   
Bmul_1925 n.d.Burkholderia multivorans ATCC 17616CP000868
AP009385.1
ABX15612.1
BAG43251.1
   
Bphy_2378 n.d.Burkholderia phymatum STM815CP001043.1
ACC71553.1
   
Bphy_3254 n.d.Burkholderia phymatum STM815CP001044.1
ACC72412.1
   
Bphyt_5838 n.d.Burkholderia phytofirmans PsJNCP001053
ACD20174.1
   
BURPS1106A_A2145 n.d.Burkholderia pseudomallei 1106aCP000573
ABN93043.1
   
BURPS1710b_A0632 n.d.Burkholderia pseudomallei 1710bCP000125
ABA51280.1
   
BURPS668_A2231 n.d.Burkholderia pseudomallei 668CP000571
ABN86034.1
   
BPSS1581 (BcsZ) n.d.Burkholderia pseudomallei K96243BX571966
CAH39055.1
   
Bcep18194_A4526 n.d.Burkholderia sp. 383CP000151
ABB08122.1
   
BTH_II0792 n.d.Burkholderia thailandensis E264; ATCC 700388CP000085
ABC35458.1
   
Bcep1808_1350 n.d.Burkholderia vietnamiensis G4CP000614
ABO54360.1
   
Bxe_B2042 n.d.Burkholderia xenovorans LB400CP000271
ABE33943.1
   
kuste3391 (BcsC) n.d.Candidatus Kuenenia stuttgartiensisCT573071
CAJ74153.1
   
endo-1,4-glucanase (fragment) 3.2.1.4
Cellulomonas udaM36503
AAA23090.1
P18336
  
Cag_0339 n.d.Chlorobium chlorochromatii CaD3CP000108
ABB27612.1
   
CV2676 (BscZ) n.d.Chromobacterium violaceum ATCC 12472AE016919
NC_005085
AAQ60346.1
NP_902346.1
   
CKO_04974 n.d.Citrobacter koseri ATCC BAA-895CP000822
ABV16018.1
   
endo-1,4-glucanase C (CelC;CelCCC) - Cel8C3.2.1.4
Clostridium cellulolyticum ATCC 35319M87018
AAA73867.1
P37699
1G4L
1G4N


endo-1,4-glucanase B (CelB) - Cel8A3.2.1.4
Clostridium josuiD16670
BAA04078.1
P37701
  
Cphy_3207 n.d.Clostridium phytofermentans ISDgCP000885
ABX43561.1
   
endo-1,4-glucanase A (CelA;Cthe_0269) - Cel8An.d.Clostridium thermocellum ATCC 27405CP000568
ABN51508.1
   
endo-1,4-glucanase A (CelA) - Cel8A3.2.1.4
Clostridium thermocellum NCIB 10682 / JW20K03088
AAA83521.1
P04955
1CEM
1IS9
1KWF
 
[A]
[A]
RALTA_B0291 n.d.Cupriavidus taiwanensis LMG 19424CU633750
CAP63489.1
   
CHU_3441 n.d.Cytophaga hutchinsonii ATCC 33406CP000383
ABG60675.1
   
CHU_1240 n.d.Cytophaga hutchinsonii ATCC 33406CP000383
ABG58512.1
   
CHU_2852 n.d.Cytophaga hutchinsonii ATCC 33406CP000383
ABG60100.1
   
CHU_3727 n.d.Cytophaga hutchinsonii ATCC 33406CP000383
ABG60960.1
   
CHU_1075 n.d.Cytophaga hutchinsonii ATCC 33406CP000383
ABG58352.1
   
Dgeo_2684 + Dgeo_2687 n.d.Deinococcus geothermalis DSM 11300CP000358
CP000358
ABF44117.1
ABF44120.1
   
Sequence 7523 from patent US 7041814 n.d.Enterobacter cloacae 15842-
ABH77680.1
   
ORF4 n.d.Enterobacter sakazakiiAM490195
CAM32315.1
   
ESA_04206 n.d.Enterobacter sakazakii ATCC BAA-894CP000783
ABU79386.1
   
Ent638_3928 n.d.Enterobacter sp. 638CP000653
ABP62583.1
   
Ent638_3936 n.d.Enterobacter sp. 638CP000653
ABP62591.1
   
ECA4373 (BcsZ) n.d.Erwinia carotovora subsp. atroseptica SCRI1043BX950851
CAG77269.1
   
endo-1,4-glucanase Y (CelY) 3.2.1.4
Erwinia chrysanthemi 3937M74044
AAA24818.1
P27032
  
endoglucanase 8Y - Cel8Y3.2.1.4
Erwinia chrysanthemi PY35AF282321
AAG49556.1
Q9APJ5
  
endoglucanase (CelA) 3.2.1.4
Erwinia rhapontici NCPPB2989AJ276358
CAB89803.1
Q9L3G9
  
ETA_33880 n.d.Erwinia tasmaniensis Et1/99CU468135
CAO98434.1
   
ECP_3631 n.d.Escherichia coli 536CP000247
ABG71607.1
   
APECO1_2917 n.d.Escherichia coli APEC O1CP000468
ABJ03013.1
   
EcolC_0186 n.d.Escherichia coli C str. ATCC 8739CP000946
ACA75867.1
   
YhjM n.d.Escherichia coli CFT073AE016768
NC_004431
AAN82779.1
NP_756205.1
   
ECDH10B_3708 n.d.Escherichia coli DH10B K-12CP000948
ACB04583.1
   
EcE24377A_4019 n.d.Escherichia coli E24377ACP000800
ABV18719.1
   
endo-1,4-glucanase (YhjM;BcsC) 3.2.1.4
Escherichia coli K12U00039
AE000430
NC_000913
AAB18508.1
AAC76556.1
NP_417988.1
P37651
  
Z4946 (YhjM) n.d.Escherichia coli O157:H7 EDL933AE005579
NC_002655
AAG58673.1
NP_290111.1
   
ECs4411 n.d.Escherichia coli O157:H7 str. SakaiAP002565
NC_002695
BAB37834.1
NP_312438.1
Q8X5L9
  
EcSMS35_3840 n.d.Escherichia coli SECEC SMS-3-5CP000970
ACB19024.1
   
UTI89_C4063 n.d.Escherichia coli UTI89CP000243
ABE09492.1
   
endo-1,4-D-glucanase (BcsZ) n.d.Escherichia coli W3110AP009048
BAE77763.1
   
endoglucanase (FSU2303) - Cel8B3.2.1.4
Fibrobacter succinogenes subsp. succinogenes S85EU055605
ABU45499.1
   
Fjoh_1022 n.d.Flavobacterium johnsoniae UW101CP000685
ABQ04055.1
   
Fjoh_3868 n.d.Flavobacterium johnsoniae UW101CP000685
ABQ06879.1
   
endo-1,4-glucanase (cmcAX) 3.2.1.4
Gluconacetobacter xylinus ATCC 23769M96060
AAA16969.1
P37696
1WZZ
[A]
endo--1,4-glucanase (Cmcase) n.d.Gluconacetobacter xylinus ATCC 53582AB091058
BAC82540.1
   
endo-1,4-glucanase (CMCase) 3.2.1.4
Gluconacetobacter xylinus BPR2001-
AB010645
AAQ38000.1
BAA31461.1
O82857
  
endoglucanase (Cmc) (fragment) n.d.Gluconacetobacter xylinus JCM7664AB015802
BAA77583.1
Q9WX59
  
HCH_06791 n.d.Hahella chejuensis KCTC 2396CP000155
ABC33415.1
   
Haur_0294 n.d.Herpetosiphon aurantiacus ATCC 23779CP000875
ABX02946.1
   
Haur_2431 n.d.Herpetosiphon aurantiacus ATCC 23779CP000875
ABX05071.1
   
Haur_0293 n.d.Herpetosiphon aurantiacus ATCC 23779CP000875
ABX02945.1
   
Sequence 11126 from patent US 6610836 n.d.Klebsiella pneumoniae-
AAR51409.1