CAZy Family GH79

CAZy ~ Carbohydrate-Active enZymes

Families

Glycoside Hydrolases

GlycosylTransferases

Polysaccharide Lyases

Carbohydrate Esterases

Carbohydrate-Binding Modules


Glycoside Hydrolase Family 79


Known Activities	-glucuronidase (EC 3.2.1.31); -4-O-methyl-glucuronidase (EC 3.2.1.-); heparanase (EC 3.2.1.-)

Mechanism	Retaining (inferred)

Catalytic Nucleophile/Base	Glu (inferred)

Catalytic Proton Donor	Glu (inferred)

3D Structure Status	Fold: ( / ) ₈ (inferred)

Clan	GH-A

Relevant Links	InterPro PFAM

Statistics	CAZy Entries (68); GenBank/GenPept (190); Swissprot (15);

Taxonomy	Bacteria(13); Eukaryota(55);


Bacteria
Protein	EC#	Organism	GenBank/GenPept		UniProt	PDB/3D
blr6802	n.d.	Bradyrhizobium japonicum USDA110	NC_004463 AP005959	NP_773442.1 BAC52067.1	Q89F99
BMA10299_A0523	n.d.	Burkholderia mallei NCTC 10229	CP000546	ABN03255.1
BMA10247_0632	n.d.	Burkholderia mallei NCTC 10247	CP000548	ABO04032.1
BMASAVP1_A1351	n.d.	Burkholderia mallei SAVP1	CP000526	ABM52247.1
BURPS1106A_1579	n.d.	Burkholderia pseudomallei 1106a	CP000572	ABN91084.1
BURPS1710b_1742	n.d.	Burkholderia pseudomallei 1710b	CP000124	ABA47936.1
BURPS668_1554	n.d.	Burkholderia pseudomallei 668	CP000570	ABN81774.1
BPSL2070	n.d.	Burkholderia pseudomallei K96243	BX571965	CAH36071.1
Mmwyl1_1639	n.d.	Marinomonas sp. MWYL1	CP000749	ABR70566.1
Saro_3674	n.d.	Novosphingobium aromaticivorans DSM 12444	CP000677	ABP64533.1
Sde_3124	n.d.	Saccharophagus degradans 2-40	CP000282	ABD82381.1
Acid_5025	n.d.	Solibacter usitatus Ellin6076	CP000473	ABJ85981.1
Acid_3120	n.d.	Solibacter usitatus Ellin6076	CP000473	ABJ84098.1


Eukaryota
Protein	EC#	Organism	GenBank/GenPept		UniProt	PDB/3D
At5g61250/MFB13.2 (GUS1)	n.d.	Arabidopsis thaliana	AY099736 BT002603 AB010073 NC_003076 NM_180907	AAM20587.1 AAO00963.1 BAB08480.1 NP_200933.1 NP_851238.1	Q9FLK8 Q8L608
At5g34940/MGG23.2 (GUS3)	n.d.	Arabidopsis thaliana	AB028613 AK229275 NM_122885	BAB10787.1 BAF01139.1 NP_198344.1	Q9FZP1
At5g07830/F13G24.30 (GUS2)	n.d.	Arabidopsis thaliana	BT015345 BT015800 AB005249 AL133421 NM_120865	AAU05468.1 AAU93572.1 BAB09947.1 CAB62595.1 NP_196400.2	Q9SDA1 Q9FF10
AN6925.2	n.d.	Aspergillus nidulans FGSC A4	AACD01000115	EAA57680.1
An14g01330	n.d.	Aspergillus niger CBS 513.88	AM270313	CAK41913.1
An14g01620	n.d.	Aspergillus niger CBS 513.88	AM270315	CAK46475.1
-glucuronidase / -4-O-methyl-glucuronidase (An02g11890)	3.2.1.31 3.2.1.-	Aspergillus niger CBS 513.88	AM270032	CAK96418.1
AO090701000905	n.d.	Aspergillus oryzae RIB 40	AP007164	BAE62550.1
AO090012000045	n.d.	Aspergillus oryzae RIB 40	AP007161	BAE60286.1
AO090011000315	n.d.	Aspergillus oryzae RIB 40	AP007171	BAE64832.1
AO090103000292 (fragment)	n.d.	Aspergillus oryzae RIB 40	AP007174	BAE65739.1
AO090012000038 (fragment)	n.d.	Aspergillus oryzae RIB 40	AP007161	BAE60281.1
Bmhepa	n.d.	Bombyx mori p50	AB079860 AB090307	BAB85191.1 BAC10612.1
heparanase	3.2.1.-	Bos taurus	AF281160 NM_174082	AAF87301.2 NP_776507.1	Q9MYY0
CNI01540	n.d.	Cryptococcus neoformans var. neoformans JEC21	AE017349	AAW45661.1
CNI01750	n.d.	Cryptococcus neoformans var. neoformans JEC21	AE017349	AAW45659.1
CNM01110	n.d.	Cryptococcus neoformans var. neoformans JEC21	AE017353	AAW46890.1
CNL06480	n.d.	Cryptococcus neoformans var. neoformans JEC21	AE017352	AAW46651.1
CH211-85E10.3-001	n.d.	Danio rerio	BX649525 BC139574	CAK05012.1 AAI39575.1
heparanase	3.2.1.-	Gallus gallus	AY037007 -	AAK82648.1 AAS29152.1	Q90YK5
hyaluronidase	3.2.1.-	Hirudinaria manillensis	- AX058912	ABH83948.1 CAC22594.1
hyaluronidase	3.2.1.-	Hirudinaria manillensis	-	ABH83946.1
hyaluronidase	3.2.1.-	Hirudinaria manillensis	- AX058910	ABH83947.1 CAC22593.1
hyaluronidase	3.2.1.-	Hirudinaria manillensis	- AX058914	ABH83949.1 CAC22595.1
Hpa2	n.d.	Homo sapiens	BC112356 - - - - AK314759 AK094037 AX100935 AX393920 AX393922 AX393924 AX393926 AL445251 AL445251 AL445251 AL445251 AL445251 AL445251 AL445251 AL445251 AL445251 AL445251 AL445251 AL445251 AL445251 AL445251 AL445251 NM_021828	AAI12357.1 AAY07213.1 ABJ35307.1 ABJ35308.1 ABJ35309.1 BAG37297.1 BAG52801.1 CAC36496.1 CAD29059.1 CAD29060.1 CAD29061.1 CAD29062.1 CAH70448.1 CAH70449.1 CAH70450.1 CAH73137.1 CAH73138.1 CAH73139.1 CAI14146.1 CAI14147.1 CAI14148.1 CAI16472.1 CAI16473.1 CAI16474.1 CAI17160.1 CAI17161.1 CAI17162.1 NP_068600.3
heparanase (endo--glucuronidase) (HPA)	3.2.1.-	Homo sapiens	AF144325 AF165154 AF152376 AF084467 AF155510 - - - - BC051321 - - - - - - - - - - - - - - AY948074 - - - - - - - AK222986 AK075400 AX034643 AX034645 AX136167 AX147946 CQ840768 CQ840772 CQ840860 CQ840864 CQ971645 CQ971649 CS051203 CS342020 CS342024 AM419200 NM_006665	AAD41342.1 AAD45379.1 AAD45669.1 AAD54516.1 AAD54941.1 AAE32409 AAE58088.1 AAE73533.1 AAE73534.1 AAH51321.1 AAN25813.1 AAN93460.1 AAN97232.1 AAP02795.1 AAQ27145.1 AAS22726.1 AAS22727.1 AAS29151.1 AAS29153.1 AAT15085.1 AAW00328.1 AAW04303.1 AAW04304.1 AAW06749.1 AAX47106.1 ABA68377.1 ABC06425.1 ABC06426.1 ABE17595.1 ABH84630.1 ABI07172.1 ABJ35310.1 BAD96706.1 BAG52128.1 CAC10139.1 CAC10140.1 CAC39726.1 CAC41180.1 CAH05691.1 CAH05692.1 CAH05695.1 CAH05696.1 CAI40110.1 CAI40111.1 CAI72097.1 CAL14864.1 CAL14865.1 CAL91960.1 NP_006656.1	Q9Y251 Q9UL39
ORF	n.d.	Hordeum vulgare subsp. vulgare	AJ495772	CAD42650.1
MG05954.4 (MGG_05954)	n.d.	Magnaporthe grisea 70-15	CH476823	EDJ96432.1
MtrDRAFT_AC144477g24v1 (fragments)	n.d.	Medicago truncatula	AC144477 AC151744 AC151744 AC144477 AC144477	ABE93311.1 ABE87276.1 ABE87275.1 ABP02759.1 ABP02760.1
MtrDRAFT_AC144477g21v1 or MtrDRAFT_AC151744g15v2	n.d.	Medicago truncatula	AC151744 AC144477	ABE87280.1 ABE93308.1
heparanase	3.2.1.-	Mus musculus	- AY077467 AY151051 AF359507 - - - - AK040471 AK154628 AX034647 NM_152803	AAE73535.1 AAL76083.1 AAN41636.1 AAQ15188.1 AAS22728.1 AAS29149.1 AAW04306.1 ABC06428.1 BAC30600.1 BAE32725.1 CAC10141.1 NP_690016.1	Q8K3K3
LOC545291	n.d.	Mus musculus	XM_619590	XP_619590.1
-glucuronidase (Nc6GAL;NCU00937.1)	3.2.1.31	Neurospora crassa OR74A	XM_959670 AB293989	XP_964763.1 BAF75800.1
NCU08179.1	n.d.	Neurospora crassa OR74A	XM_954479	XP_959572.1
heparanase (fragment)	n.d.	Oryctolagus cuniculus	EF472899	ABQ23973.1
Os07g0598400	n.d.	Oryza sativa (japonica cultivar-group)	AP003915 AP008213	BAC83217.1 BAF22096.1
Os02g0802200	n.d.	Oryza sativa (japonica cultivar-group)	AP005056 AP007227 AP008208 CM000139.1	BAD36026.1 BAD36734.1 BAF10334.1 EAZ24974.1
Os12g0578400	n.d.	Oryza sativa (japonica cultivar-group)	AP008218	BAF30141.1
Os03g0211700	n.d.	Oryza sativa (japonica cultivar-group)	AP008209	BAF11264.1
Os06g0179000	n.d.	Oryza sativa (japonica cultivar-group)	AP003019 AP003019 AP008212	BAC22238.1 BAD72300.1 BAF18881.1	Q8H615
unnamed protein product	n.d.	Podospora anserina	CU633446	CAP60949.1
unnamed protein product	n.d.	Podospora anserina	CU633866	CAP64824.1
unnamed protein product	n.d.	Podospora anserina	CU633438	CAP59870.1
heparanase	3.2.1.-	Rattus norvegicus	- AF184967 AF359508 - AX034649 NM_022605	AAE73536.1 AAF04563.1 AAQ15189.1 AAS29150.1 CAC10143.1 NP_072127.1	Q9QZF8
-glucuronidase (SGUS)	3.2.1.-	Scutellaria baicalensis	AB040072	BAA97804.1	Q9LRC8
heparanase (hpA)	n.d.	Spalax carmeli	AM085492	CAJ30019.1
heparanase (hpA)	n.d.	Spalax galili	AM085490	CAJ30017.1
heparanase (hpA)	n.d.	Spalax golani	AM085491	CAJ30018.1
heparanase (hpA)	n.d.	Spalax judaei	AM085493 AM085494	CAJ30020.1 CAJ30021.1
Sequence 115106 from patent US 7214786	n.d.	Triticum aestivum	ABT27636	ABT27636.1
VITISV_038549	n.d.	Vitis vinifera	AM484986	CAN81917.1
Unknown (protein for MGC:135874 IMAGE:7714017)	n.d.	Xenopus tropicalis N6 (Nigerian 6th generation inbred)	BC160516	AAI60516.1
Hypro2 (fragment)	n.d.	Zea mays	AF391808	AAK73118.1	Q9ATW5
unknown (ZM_BFb0129F04)	n.d.	Zea mays B73	BT034304	ACF79309.1
unknown (ZM_BFb0097P08)	n.d.	Zea mays B73	BT036139	ACF81144.1