CAZy Family GH74

CAZy ~ Carbohydrate-Active enZymes

Families

Glycoside Hydrolases

GlycosylTransferases

Polysaccharide Lyases

Carbohydrate Esterases

Carbohydrate-Binding Modules


Glycoside Hydrolase Family 74


Known Activities	endoglucanase (EC 3.2.1.4); oligoxyloglucan reducing end-specific cellobiohydrolase (EC 3.2.1.150); xyloglucanase (EC 3.2.1.151)

Mechanism	Inverting

Catalytic Nucleophile/Base	Asp (experimental)

Catalytic Proton Donor	Asp (experimental)

3D Structure Status	Fold: 7-fold -propeller

Clan	none

Statistics	CAZy Entries (38); GenBank/GenPept (56); Uniprot (10); 3D(3) : PDB(5);

Taxonomy	Bacteria(23); Eukaryota(15);

3D Display	GH74_3D


Bacteria
Protein	EC#	Organism	GenBank/GenPept		UniProt	PDB/3D
Acel_0618	n.d.	Acidothermus cellulolyticus 11B; ATCC 43068	CP000481 - - -	ABK52391.1 ACE14916.1 ACE14917.1 ACE14920.1
BamMC406_4813	n.d.	Burkholderia ambifaria MC40-6	CP001026	ACB67266.1
Csac_1085	n.d.	Caldicellulosiruptor saccharolyticus DSM 8903	CP000679	ABP66699.1
ORF5	n.d.	Caldicellulosiruptor sp. Tok7B.1	AF078038	AAK06388.1	Q9AQH0
CJA_2477 - Gly74A	n.d.	Cellvibrio japonicus Ueda107	CP000934	ACE84745.1
CAC0919	n.d.	Clostridium acetobutylicum ATCC 824	AE007608 NC_003030	AAK78895.1 NP_347555.1	Q97KK0
Cthe_1398 (XghA) - Xgh74A	n.d.	Clostridium thermocellum ATCC 27405	CP000568	ABN52629.1
-1,4-xyloglucan hydrolase (XghA) - Xgh74A	3.2.1.151	Clostridium thermocellum F7	AJ585344	CAE51306.1		2CN2 2CN3	[A] [A]
CHU_1155	n.d.	Cytophaga hutchinsonii ATCC 33406	CP000383	ABG58430.1
Haur_2138	n.d.	Herpetosiphon aurantiacus ATCC 23779	CP000875	ABX04778.1
xyloglucanase (Xeg)	3.2.1.151	Jonesia sp. DSM 14140	AX565635	CAD58415.1
xyloglucanase - Xeg74	3.2.1.151	Paenibacillus sp. KM21	AB212090	BAE44527.1
SAV1856	n.d.	Streptomyces avermitilis MA-4680	AP005028 NC_003155	BAC69567.1 NP_823032.1
SAV2574	n.d.	Streptomyces avermitilis MA-4680	AP005031 NC_003155	BAC70285.1 NP_823750.1
SCO6545 or SC5C7.30c	n.d.	Streptomyces coelicolor A3(2)	AL031515 NC_003888	CAA20642.1 NP_630626.1	O86727
xyloglucanase (Tfu_1612) - Xeg74	3.2.1.151	Thermobifida fusca YX	NZ_AAAQ01000018 CP000088	ZP_00056977.1 AAZ55647.1		1WWO	[1]
endo-1,4-glucanase (TM0305) - Cel74	3.2.1.4	Thermotoga maritima MSB8	AE001712 NC_000853	AAD35393.1 NP_228117.1	Q9WYE1
TRQ2_0626	n.d.	Thermotoga sp. RQ2	CP000969	ACB08979.1
XAC1770 (CelA)	n.d.	Xanthomonas axonopodis pv. citri str. 306	AE011809 NC_003919	AAM36634.1 NP_642098.1
xcc-b100_2510	n.d.	Xanthomonas campestris pv. campestris B100	AM920689	CAP51870.1
XC_2483	n.d.	Xanthomonas campestris pv. campestris str. 8004	CP000050	AAY49533.1
XCC1752	n.d.	Xanthomonas campestris pv. campestris str. ATCC 33913	AE012276 NC_003902	AAM41043.1 NP_637119.1
XCV1802	n.d.	Xanthomonas campestris pv. vesicatoria str. 85-10	AM039952	CAJ23479.1


Eukaryota
Protein	EC#	Organism	GenBank/GenPept		UniProt	PDB/3D
Cel6	n.d.	Agaricus bisporus D649	AJ292929 AJ534359	CAC02964.1 CAD58875.1	Q9P4T8 Q8J1H7
avicelase III (AviIII;FIII Avicelase)	3.2.1.4	Aspergillus aculeatus	- AB015511	ACE14921.1 BAA29031.1	O74170
oligoxyloglucan reducing end-specific xyloglucanobiohydrolase (OREX;AN1542.2)	3.2.1.150	Aspergillus nidulans FGSC A4	AACD01000025	EAA64249.1
AN5061.2	n.d.	Aspergillus nidulans FGSC A4	AACD01000085	EAA60055.1
xyloglucanase C (EglC)	3.2.1.151	Aspergillus niger	AY040839	AAK77227.1	Q8TFP1
An01g01870 (EglC)	n.d.	Aspergillus niger CBS 513.88	AM269954	CAK43558.1
xyloglucanase (Xgl) (fragment) - Xgl74A	3.2.1.151	Chrysosporium lucknowense
oligoxyloglucan reducing end-specific cellobiohydrolase (OXG-RCBH)	3.2.1.150	Geotrichum sp. M128	AB089343 AX924429 AX924431	BAC22065.1 CAF02212.1 CAF02249.1	Q8J0D2	1SQJ 2EBS	[A] [A]
xyloglucanase	3.2.1.151	Geotrichum sp. M128	AB116528	BAD11543.1
xyloglucanase (Egl6) - Cel74A	3.2.1.151	Hypocrea jecorina QM6a	AY281371 - -	AAP57752.1 ABH71452.1 ABJ18610.1	Q7Z9M8
MG00582.4	n.d.	Magnaporthe grisea 70-15	AACU01001430 XM_368662 XM_368662	EAA48924.1 XP_368662.1 XP_368662.2
NCU05955.1	n.d.	Neurospora crassa OR74A	AABX01000439 XM_325809	EAA29333.1 XP_325810.1
xyloglucanase - Xgh74B	3.2.1.151	Phanerochaete chrysosporium K-3	AB308054	BAF95189.1
unnamed protein product	n.d.	Podospora anserina	CU633895	CAP66717.1
-glucosidase (fragment)	3.2.1.- 2.4.1.-	Stachybotrys sp. N1