CAZy ~ Carbohydrate-Active enZymes


   
Glycoside Hydrolase Family 5
  
Known Activitieschitosanase (EC 3.2.1.132); -mannosidase (EC 3.2.1.25); Cellulase (EC 3.2.1.4); glucan 1,3--glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); glucan endo-1,6--glucosidase (EC 3.2.1.75); mannan endo-1,4--mannosidase (EC 3.2.1.78); Endo-1,4--xylanase (EC 3.2.1.8); cellulose 1,4--cellobiosidase (EC 3.2.1.91); endo-1,6--galactanase (EC 3.2.1.-); -1,3-mannanase (EC 3.2.1.-); xyloglucan-specific endo--1,4-glucanase (EC 3.2.1.151)
 
MechanismRetaining
 
Catalytic Nucleophile/BaseGlu (experimental)
 
Catalytic Proton DonorGlu (experimental)
 
3D Structure StatusFold: ( / ) 8
 
ClanGH-A
 
Noteformerly known as cellulase family A.
 
Relevant LinksHOMSTRAD   InterPro   PFAM   PROSITE   
 
StatisticsCAZy Entries (1340);  GenBank/GenPept (2163);  Swissprot (332);  3D(24) : PDB(73); cryst(1);
 
TaxonomyArchaea(8);  Bacteria(836);  Eukaryota(468);  unclassified(28);  
 
3D DisplayGH5_3D
 
        
        Archaea          
ProteinEC#OrganismGenBank/GenPeptUniProtPDB/3D
Cmaq_0936 n.d.Caldivirga maquilingensis IC-167CP000852
ABW01768.1
   
PTO1452 n.d.Picrophilus torridus DSM 9790AE017261
AAT44037.1
   
PAB0632 n.d.Pyrococcus abyssi GE5 OrsayAJ248285
NC_000868
CAB49854.1
NP_126623.1
Q9V052
  
endoglucanase (PH1171) 3.2.1.4
Pyrococcus horikoshii OT3-
-
AP000005
NC_000961
AAQ31832.1
AAQ31833.1
BAA30271.1
NP_143072.1
O58925
  
SSO3007 n.d.Sulfolobus solfataricus P2AE006891
AL512980
NC_002754
AAK43109.1
CAC24030.1
NP_344319.1
Q97UK4
  
Tpen_1672 n.d.Thermofilum pendens Hrk 5CP000505
ABL79067.1
   
Sequence 2 from patent US 6329187 n.d.thermophilic archaea-
AAQ77850.1
   
TVG0696003 n.d.Thermoplasma volcanium GSS1AP000993
NC_002689
BAB59829.1
NP_111209.1
Q97AX2
  
 
        
        Bacteria          
ProteinEC#OrganismGenBank/GenPeptUniProtPDB/3D
Acid345_0317 n.d.Acidobacteria bacterium Ellin345CP000360
ABF39322.1
   
Acid345_1689 n.d.Acidobacteria bacterium Ellin345CP000360
ABF40690.1
   
-mannanase (ManA) n.d.Acidothermus cellulolyticus-
-
-
-
-
ABJ41265.1
ABJ41262.1
ABJ41264.1
ABJ41266.1
ABJ41263.1
   
endo-1,4-glucanase E1 (Acel_0614) - Cel5A3.2.1.4
Acidothermus cellulolyticus 11B; ATCC 43068U33212
-
CP000481
AX467594
AAA75477.1
ABH84883.1
ABK52387.1
CAD42489.1
P54583
1C0D
1ECE
1VRX
[B]
[A]
[A]
Acel_0616 n.d.Acidothermus cellulolyticus 11B; ATCC 43068CP000481
ABK52389.1
   
Aave_2102 n.d.Acidovorax avenae subsp. citrulli AAC00-1CP000512
ABM32683.1
   
Aave_2924 n.d.Acidovorax avenae subsp. citrulli AAC00-1CP000512
ABM33492.1
   
Gly (fragment) n.d.Acinetobacter baumannii 7037EF063111
ABL75132.1
   
Gly (fragment) n.d.Acinetobacter baumannii 7037EF063111
ABL75136.1
   
endo-1,4-glucanase 3.2.1.4
Actinomyces sp. 40U94825
AAC06196.1
O66064
  
xylanase D (XynD) 3.2.1.8
Aeromonas punctata ME-1U86340
AAB63573.1
O24852
  
xylanase 3 (Xyn3) 3.2.1.8
Aeromonas punctata W-61D88553
BAA13641.1
P70733
  
-1,4-mannanase n.d.Alicyclobacillus acidocaldariusAY634280
AAT47714.1
   
Sequence 1 from patent US 6190899 n.d.alkaliphilic Actinomycete
AAE60112.1
   
PCZA361.14 n.d.Amycolatopsis orientalisAJ223998
CAA11771.1
O52801
  
endo-1,4-glucanase (CelD) 3.2.1.4
Anaerocellum thermophilumZ77855
CAB01405.1
Q59154
  
endo-1,4-glucanase (CelB) 3.2.1.4
Anaerocellum thermophilumZ86104
CAB06784.1
P96310
  
Anae109_4201 n.d.Anaeromyxobacter sp. Fw109-5CP000769
ABS28379.1
   
azo2311 n.d.Azoarcus sp. BH72AM406670
CAL94928.1
   
endoglucanase (EglA;azo2236) 3.2.1.4
Azoarcus sp. BH72DQ294349
AM406670
ABB92850.1
CAL94853.1
   
endoglucanase (Egl;AZC_1301) n.d.Azorhizobium caulinodans ORS 571AP009384
BAF87299.1
   
endo-1,4-glucanase 5A - Cel5A3.2.1.4
Bacillus agaradhaerensAF067428
AAC19169.1
O85465
1A3H
1E5J
1H11
1H2J
1H5V
1HF5
1HF6
1HF7
1OCQ
1QHZ
1QI0
1QI2
1W3K
1W3L
2A3H
2V38
3A3H
4A3H
5A3H
6A3H
7A3H
8A3H
 
[A]
[A]
[A]
[A]
A
[A]
A
[A]
[A]
[A]
[A]
[A]
[A]
 
[A]
 
[A]
[A]
[A]
[A]
[A]
Cel n.d.Bacillus agaradhaerens DSM 8721AJ537597
CAD61244.1
   
RBAM_018140 n.d.Bacillus amyloliquefaciens FZB42CP000560
AJ576102
ABS74177.1
CAE11246.1
   
RBAM_018100 n.d.Bacillus amyloliquefaciens FZB42CP000560
AJ576102
ABS74173.1
CAE11243.1
   
endoglucanase A (EngA) n.d.Bacillus amyloliquefaciens UMAS1002AF363635
AAL99668.1
Q8RPQ6
  
-mannanase n.d.Bacillus circulansAY540747
AAS48170.1
   
-mannanase (TM1) 3.2.1.78
Bacillus circulansAY623903
AAT39478.1
   
-mannanase (Man1;ManB48) 3.2.1.78
Bacillus circulans CGMCC 1416AY907668
AAX87002.1
   
-mannanase 3.2.1.78
Bacillus circulans K-1AB007123
BAA25878.1
O66185
  
ABC0320 n.d.Bacillus clausii KSM-K16AP006627
BAD62862.1
   
-glucanase (CelB;BH0603) 3.2.1.-
Bacillus halodurans C-125AP001509
NC_002570
BAB04322.1
NP_241469.1
Q9KF82
  
BLi02088 or BL01471 (BglC) n.d.Bacillus licheniformis DSM 13 ATCC 14580CP000002
AE017333
AAU23613.1
AAU40977.1
   
BLi01882 or BL01230 n.d.Bacillus licheniformis DSM 13 ATCC 14580CP000002
AE017333
AAU23417.1
AAU40777.1
   
BLi01883 / BL01229 n.d.Bacillus licheniformis DSM 13 ATCC 14580CP000002
AE017333
AAU23418.1
AAU40778.1
   
CelB n.d.Bacillus licheniformis F11AM183792
CAJ70720.1
   
endo--1,4-glucanase (CelA) n.d.Bacillus licheniformis F11CP000002
AM183790
AAU23613.2
CAJ70714.1
   
CelB n.d.Bacillus licheniformis F5AM183791
CAJ70717.1
   
endo--1,4-glucanase (CelA) n.d.Bacillus licheniformis F5AM183789
CAJ70710.1
   
endo--1,4-glucanase (Cel5A) - Cel5A3.2.1.4
Bacillus licheniformis GXN151AY291583
AX954763
AAP51020.1
CAF05574.1
Q7X3S6
  
endoglucanase (CelA) 3.2.1.4
Bacillus licheniformis MD1AJ616005
CAE82178.1
   
CelB n.d.Bacillus licheniformis MD1AJ786638
CAH10344.1
   
YdhT (fragment) n.d.Bacillus licheniformis MD1AJ786638
CAH10345.1
   
bifunctional cellulase chitosanase (CelA) 3.2.1.4

3.2.1.132		Bacillus licheniformis NBL420AY039744
AAK73277.1
Q93LI9
  
BPUM_1747 n.d.Bacillus pumilus SAFR-032CP000813
ABV62419.1
   
BPUM_1561 n.d.Bacillus pumilus SAFR-032CP000813
ABV62243.1
   
-mannanase n.d.Bacillus sp.-
AAQ31834.1
   
unnamed protein product n.d.Bacillus sp.-
AX643592
CQ827968
ABH73763.1
CAD67813.1
CAH03186.1
   
Sequence 22 from patent US 6566114 n.d.Bacillus sp.-
AAQ31844.1
   
Sequence from patents n.d.Bacillus sp.-
-
-
-
-
-
-
AAN27517.1
AAN27518.1
AAQ31837.1
AAQ79152.1
AAQ79153.1
ABC13790.1
ABC13791.1
   
Sequence 16 from patent US 6566114 n.d.Bacillus sp.-
AAQ31841.1
   
endo-1,4-glucanase - Cel5A3.2.1.4
Bacillus sp. 1139M15743
-
D00066
AAA22305.1
ACE14924.1
BAA00045.1
P06564
  
endo-1,4-glucanase 3.2.1.4
Bacillus sp. 22-28D85236
BAA12744.1
Q45554
  
endo-1,4-glucanase 3.2.1.4
Bacillus sp. 5HAB016164
BAA31712.1
O83012
  
CelS 3.2.1.4
Bacillus sp. 79-23AF045482
AAC02536.1
O52731
  
Sequence 12 from patent US 6566114 n.d.Bacillus sp. AAI12-
AAQ31839.1
   
Sequence 20 from patent US 7183093 (fragment) n.d.Bacillus sp. AAI12ABP12275
ABP12275.1
   
endo-1,4-glucanase A (CelA) 3.2.1.4
Bacillus sp. BP-23Y12512
CAA73113.1
O08342
  
unnamed protein product n.d.Bacillus sp. CBS 669.93-
-
AX665431
AAE86309.1
AAV25062.1
CAD82874.1
   
cellulase 3.2.1.4
Bacillus sp. CBS 670.93-
A76937
A79880
AX665429
AAV25061.1
CAB58698.1
CAB59165.1
CAD82873.1
 1LF1
A
endo-1,4-glucanase (Cel) 3.2.1.4
Bacillus sp. D04U27084
AAC43478.1
Q45430
  
endo--1,4-glucanase (GluY) n.d.Bacillus sp. HB102AY665770
AAU08303.1
   
endo-1,4--D-glucanase (GluB) (fragment) n.d.Bacillus sp. HB104AY898659
AAX18650.1
   
cellulase (Cel1) n.d.Bacillus sp. HY2-3AY766381
AAV34758.1
   
-mannanase - Man5An.d.Bacillus sp. JAMB-602AB119999
BAD99527.1
 1WKY
[A]
endo-1,4-glucanase K 3.2.1.4
Bacillus sp. KSM-635M27420
AAA22304.1
P19424
1G01
1G0C
[A]
[A]
endo-1,4-glucanase 3.2.1.4
Bacillus sp. KSM-64M84963
-
CS097338
CS144750
AAA73189.1
ACE14925.1
CAJ00039.1
CAJ28077.1
Q59241
  
endoglucanase N252 (Egl252) 3.2.1.4
Bacillus sp. KSM-N252AB057671
BAB62295.1
Q93R81
  
cellulase 3.2.1.4
Bacillus sp. KSM-S237-
-
AB018420
AX923058
CS097336
CS144748
ABH71811.1
ACE14923.1
BAB19360.1
CAF02232.1
CAJ00038.1
CAJ28076.1
Q9F216
  
endo-1,4-glucanase C (CelC;EgC;Cel2) 3.2.1.4
Bacillus sp. N-4M25500
AAA22306.1
P19570
  
endo-1,4-glucanase A (CelA;EgA) 3.2.1.4
Bacillus sp. N-4M14781
AAA22301.1
P06566
  
endo-1,4-glucanase B (CelB;EgB) 3.2.1.4
Bacillus sp. N-4M14729
AAA22299.1
P06565
  
-mannanase (ManA) 3.2.1.78
Bacillus sp. N16-5AY534912
AAT06599.1
   
endo-1,4-glucanase B1 3.2.1.4
Bacillus sp. N186-1Z33876
CAA83942.1
Q59232
  
endo-1,4--glucanase (GluD) n.d.Bacillus sp. NW-2004aAY663839
AAT97264.1
   
endo-1,4--glucanase (GluG) (fragment) n.d.Bacillus sp. NW-2004bAY647197
AAT97263.1
   
cellulase n.d.Bacillus sp. WRD-2AY859492
AAX54913.1
   
endo-1,4-glucanase 3.2.1.4
Bacillus subtilisM28332
AAA22307.1
Q45532
  
cellulase C (CelC) n.d.Bacillus subtilis A8-8AY183475
AAO63626.1
   
endo-1,4--glucanase (GlnC) (probable fragment) n.d.Bacillus subtilis ATTCAU195AY137375
AAN07019.1
   
YnfF n.d.Bacillus subtilis ATTCAU195AY137375
AAN07016.1
   
-glucanase n.d.Bacillus subtilis BS-2EF418013
EU022560
ABO37787.1
ABS70712.1
   
endo-1,4-glucanase 3.2.1.4
Bacillus subtilis BSE616D01057
BAA00859.1
P23549
  
endo-1,4--glucanase (EglS) n.d.Bacillus subtilis C-36DQ782954
ABG78039.1
   
endo-1,4--glucanase 3.2.1.4
Bacillus subtilis CHZ1AY044252
AAK94871.1
Q93LD0
  
endo--1,4-glucanase 3.2.1.4
Bacillus subtilis CK-2X67044
CAA47429.1
   
endo-1,4-glucanase (BglC;Gld) 3.2.1.4
Bacillus subtilis DLGM16185
AAA22496.1
P07983
  
cellulase (CelDR) 3.2.1.4
Bacillus subtilis DREU130452
ABV45393.1
   
endo--1,4-glucanase (Egl499) 3.2.1.4
Bacillus subtilis JA18DQ116829
AAZ22322.1
   
endo-1,4-glucanase n.d.Bacillus subtilis PAP115X04689
CAA28392.1
   
unnamed protein product n.d.Bacillus subtilis PAP115X04689
CAA28392.1
   
endo-1,4-glucanase (EglS;BglC;Gld;BSU18130) 3.2.1.4
Bacillus subtilis subsp. subtilis str. 168Z29076
Z73234
Z99113
NC_000964
CAA82317.1
CAA97610.1
CAB13696.2
NP_389695.1
P10475