CAZy ~ Carbohydrate-Active enZymes


   
Glycoside Hydrolase Family 48
  
Known Activitiesendoglucanase (EC 3.2.1.4); chitinase (EC 3.2.1.14); cellobiohydrolases (EC 3.2.1.-); endo-processive cellulases (EC 3.2.1.-)
 
MechanismInverting
 
Catalytic Nucleophile/BaseNot known
 
Catalytic Proton DonorGlu
 
3D Structure StatusFold: ( / ) 6
 
ClanGH-M
 
Noteformerly known as cellulase family L. Some cellobiohydrolases of this family have been reported to act from the reducing ends of cellulose (EC 3.2.1.-), while others have been reported to operate from the non-reducing ends to liberate cellobiose or cellotriose or cellotetraose (EC 3.2.1.-). This family also contains endo-processive cellulases (EC 3.2.1.-), whose activity is hard to distinguish from that of cellobiohydrolases.
 
Relevant LinksHOMSTRAD   InterPro   PFAM   PRINTS   
 
StatisticsCAZy Entries (36);  GenBank/GenPept (46);  Swissprot (14);  3D(2) : PDB(12);
 
TaxonomyBacteria(31);  Eukaryota(5);  
 
3D DisplayGH48_3D
 
        
        Bacteria          
ProteinEC#OrganismGenBank/GenPeptUniProtPDB/3D
Acel_0617 n.d.Acidothermus cellulolyticus 11B; ATCC 43068CP000481
ABK52390.1
   
cellulase (CelA) 3.2.1.-

3.2.1.4
Anaerocellum thermophilumZ86105
CAB06786.1
P96311
  
BLi01881 or BL01231 n.d.Bacillus licheniformis DSM 13 ATCC 14580CP000002
AE017333
AAU23416.1
AAU40776.1
   
CelC (fragment) n.d.Bacillus licheniformis F11AM183792
CAJ70719.1
   
CelC (fragment) n.d.Bacillus licheniformis F5AM183791
CAJ70716.1
   
CelC (fragment) n.d.Bacillus licheniformis MD1AJ786638
CAH10343.1
   
BPUM_1559 n.d.Bacillus pumilus SAFR-032CP000813
ABV62241.1
   
processive glycoside hydrolase Cel48A - Cel48An.d.Bacteroides cellulosolvensAY374129
AAR23324.1
   
CelA 3.2.1.4
Caldicellulosiruptor saccharolyticusM36063
L32742
AAA72860.1
AAA91086.1
P22534
  
Csac_1076 n.d.Caldicellulosiruptor saccharolyticus DSM 8903CP000679
ABP66690.1
   
cellobiohydrolase B (CbhB;CenE) - Cel48A3.2.1.91
Cellulomonas fimiL29042
L38827
AAA50257.1
AAB00822.1
P50899
  
CelF (CAC0911) - Cel48An.d.Clostridium acetobutylicum ATCC 824AE007607
NC_003030
AAK78887.1
NP_347547.1
Q97KK7
  
processive endo-cellulase (CelF) - Cel48F3.2.1.4
Clostridium cellulolyticum ATCC 35319M87018
U30321
AAA73866.1
AAB41452.1
P37698
1F9D
1F9O
1FAE
1FBO
1FBW
1FCE
1G9G
1G9J
2QNO
2QNO
[A]
[A]
[A]
[A]
[A]
 
[A]
[A]

[A]
exoglucanase S (ExgS;P70) 3.2.1.91
Clostridium cellulovoransU34793
U34793.3
AAC38571.2
AAC38571.3
O65986
  
CelD n.d.Clostridium josuiAB004845
BAA32430.1
O82831
  
Cphy_3368 n.d.Clostridium phytofermentans ISDgCP000885
ABX43721.1
   
cellodextrinohydrolase (avicelase II) (CelY) 3.2.1.-
Clostridium stercorariumZ69359
CAA93280.1
P50900
  
Cthe_2089 (CelS) - Cel48A=Cel48Sn.d.Clostridium thermocellum ATCC 27405CP000568
ABN53296.1
   
Cthe_0071 (CelY) - Cel48B=Cel48Yn.d.Clostridium thermocellum ATCC 27405CP000568
ABN51312.1
   
1,4--glucanase (CelY) n.d.Clostridium thermocellum F7AJ863163
CAI06105.1
   
CelS - Cel48A3.2.1.-
Clostridium thermocellum F7L06942
AAA23226.1
P38686
1L1Y
1L2A
[D]
[E]
HCH_02465 n.d.Hahella chejuensis KCTC 2396CP000155
ABC29272.1
   
Haur_0295 n.d.Herpetosiphon aurantiacus ATCC 23779CP000875
ABX02947.1
   
Cel48 n.d.Myxobacter sp. AL-1DQ403144
ABD64772.1
   
cellobiohydrolase - Cel48C3.2.1.-
Paenibacillus barcinonensisAJ488933
CAD32945.1
Q8KKF7
  
cellulase - Cel48An.d.Ruminococcus albus 8AY422811
AAR01217.1
   
Sare_3180 n.d.Salinispora arenicola CNS-205CP000850
ABV98987.1
   
Strop_2957 n.d.Salinispora tropica CNB-440CP000667
ABP55395.1
   
SAV1855 (GuxA3) n.d.Streptomyces avermitilis MA-4680AP005028
NC_003155
BAC69566.1
NP_823031.1
   
SCO6546 (SC5C7.31c) n.d.Streptomyces coelicolor A3(2)AL031515
NC_003888
CAA20643.1
NP_630627.1
O86728
  
exocellulase (E6;CelF;Tfu_1959) - Cel48A3.2.1.-
Thermobifida fusca YXAF144563
CP000088
AAD39947.1
AAZ55992.1
Q9XCD4
  
 
        
        Eukaryota          
ProteinEC#OrganismGenBank/GenPeptUniProtPDB/3D
chitinase (active phase-associated protein I) (Apap1) 3.2.1.14
Gastrophysa atrocyaneaAB241611
BAE94320.1
   
active phase-associated protein II (Apap2) n.d.Gastrophysa atrocyaneaAB241612
BAE94321.1
   
cellulose 1,4--cellobiosidase (Cbh1) n.d.Otiorhynchus sulcatusAJ829763
AJ829764
CAH25542.1
CAH25543.1
   
cellulase Cel48A - Cel48An.d.Piromyces equiAF449413
AAN76735.1
Q8J1E2
  
cellulase Cel48A - Cel48An.d.Piromyces sp. E2AF449412
AAN76734.1
Q8J1E3
  
 


  Last update: 2008 Aug 01   © Copyright 1998-2008 AFMB - CNRS - Universités Aix-Marseille I & II