CAZy Family GH2

CAZy ~ Carbohydrate-Active enZymes

Glycoside Hydrolases

GlycosylTransferases

Polysaccharide Lyases

Carbohydrate Esterases

Carbohydrate-Binding Modules

Acknowledgments


Glycoside Hydrolase Family 2


Known Activities	-galactosidase (EC 3.2.1.23) ; -mannosidase (EC 3.2.1.25); -glucuronidase (EC 3.2.1.31); mannosylglycoprotein endo--mannosidase (EC 3.2.1.152); exo--glucosaminidase (EC 3.2.1.-)

Mechanism	Retaining

Catalytic Nucleophile/Base	Glu (experimental)

Catalytic Proton Donor	Glu (experimental)

3D Structure Status	Fold: ( / ) ₈

Clan	GH-A

Relevant Links	CAZypedia HOMSTRAD InterPro PFAM PRINTS PROSITE

Statistics	CAZy Entries (1100); GenBank/GenPept (1400); Uniprot (127); 3D(9) : PDB(50);

Taxonomy	Archaea( 0 / 3 ); Bacteria( 8 / 983 ); Eukaryota( 1 / 112 ); unclassified( 0 / 2 );

Regular Display	GH2


Bacteria
Protein	EC#	Organism	GenBank/GenPept	UniProt	PDB/3D

exo--glucosaminidase / exochitosanase (CsxA)	3.2.1.-	Amycolatopsis orientalis	AAX62629.1 AAX62629.2		2VZO 2VZS 2VZT 2VZU 2VZV	A A A A A
-galactosidase (LacZ)	3.2.1.23	Arthrobacter sp. C2-2	CAD29775.1	Q8KRF6	1YQ2	A
BF0328		Bacteroides fragilis NCTC 9343 ATCC 25285 = NCTC 9343	CAH06099.1		3CMG	A
BT1626		Bacteroides thetaiotaomicron VPI-5482	AAO76733.1 NP_810539.1		3BGA	B
-mannosidase (BT0458) - Man2A	3.2.1.25	Bacteroides thetaiotaomicron VPI-5482	AAO75565.1 NP_809371.1		2JE8 2VJX 2VL4 2VMF 2VO5 2VOT 2VQT 2VQU 2VR4	A A A A A A A A A
BT3179		Bacteroides thetaiotaomicron VPI-5482	AAO78285.1 NP_812091.1		3DEC	A
-glucuronidase (UidA;GusA;GurA)	3.2.1.31	Escherichia coli K-12	AAB30197.1 AAA68923.1 BAA15368.1 AAC74689.1 NP_416134.1 AAR75623.1 ABE20937.1 CAJ55495.1 CAJ55496.1 CAJ55497.1 CAJ55498.1 CAJ55499.1 CAJ55500.1	P05804	1KZ3 1UL8 1YDQ
-galactosidase Z (LacZ)	3.2.1.23	Escherichia coli K-12	CAA23570.1 AAA24053.1 CAA23573.1 AAB18068.1 AAC73447.1 NP_414878.1 AAW06767.1 AAY73171.1	P00722	1BGL 1BGM 1DP0 1F49 1F4A 1F4H 1GHN 1GHO 1HN1 1JYN 1JYV 1JYW 1JYX 1JYY 1JYZ 1JZ0 1JZ1 1JZ2 1JZ3 1JZ4 1JZ5 1JZ6 1JZ7 1JZ8 1PX3 1PX4 3DYM 3DYO	A I A A A A I A A A A A A I A I A A A A A A A A A A A


Eukaryota
Protein	EC#	Organism	GenBank/GenPept	UniProt	PDB/3D

-glucuronidase b (GusB)	3.2.1.31	Homo sapiens	AAA52561.1 AAA52622.1 NP_000172.1 CAC41170.1 AAH14142.1 AAQ96851.1 AAR75622.1 BAD97126.1 ABH92596.1 BAG35619.1 BAG64768.1 BAG61991.1 ACH09936.1	P08236	1BHG	B

Last update: 2008 Dec 17 © Copyright 1998-2008 AFMB - CNRS - Universités Aix-Marseille I & II