 CAZy ~ Carbohydrate-Active enZymes
|
| Glycoside Hydrolase Family 20 |
| Known Activities |  -hexosaminidase (EC 3.2.1.52); lacto-N-biosidase (EC 3.2.1.140); -1,6-N-acetylglucosaminidase) (EC 3.2.1.-) |
| Mechanism | Retaining |
| Catalytic Nucleophile/Base | carbonyl oxygen of C-2 acetamido group of substrate |
| Catalytic Proton Donor | Glu |
| 3D Structure Status | Fold: ( /  ) 8 |
| Clan | GH-K |
| Relevant Links | HEXAdb HEXBdb HOMSTRAD InterPro PFAM PRINTS Tay-Sachs Disease |
| Statistics | CAZy Entries (491); GenBank/GenPept (753); Uniprot (99); 3D(6) : PDB(24); |
| Taxonomy | Archaea( 0 / 2 ); Bacteria( 4 / 356 ) ; Eukaryota( 2 / 133 ); |
| Regular Display | GH20 |
Bacteria  | ||||||
| Protein | EC# | Organism | GenBank/GenPept | UniProt | PDB/3D | |
| dispersin B (-1,6-N-acetylglucosaminidase) (DspB) | 3.2.1.- | Aggregatibacter actinomycetemcomitans CU1000 | AAP31025.1 | Q840G9 | 1YHT | A |
| chitobiase (Chb;Ctb) | 3.2.1.52 | Serratia marcescens 2170 | AAB03808.1 | Q54468 | 1C7S 1C7T 1QBA 1QBB | A A A A |
| N-acetyl--glucosaminidase (GcnA) | 3.2.1.52 | Streptococcus gordonii FSS2 | AAS02154.1 | 2EPK 2EPL 2EPM 2EPN 2EPO | X X X B B | |
| N-acetyl -glucosaminidase (Hex) | 3.2.1.52 | Streptomyces plicatus | AAC38798.3 | O85361 | 1HP4 1HP5 1JAK 1M01 1M03 1M04 | A A A A A A |
| Eukaryota | ||||||
| Protein | EC# | Organism | GenBank/GenPept | UniProt | PDB/3D | |
| -N-acetylglucosaminidase B (-chain) (HexB) | 3.2.1.52 | Homo sapiens | AAA51828.1 AAA52645.1 AAA51829.1 AAA68620.1 NP_000512.1 AAH17378.1 AAM46114.1 AAP88921.1 AAV48875.1 | P07686 | 1NOU 1NOW 1NP0 1O7A 2GJX 2GK1 | B A A C B B |
| N-acetyl -glucosaminidase (-chain) (HexA) | 3.2.1.52 | Homo sapiens | AAB00965.1 AAA51827.1 AAD13932.1 NP_000511.1 AAH18927.1 AAH01138.2 AAQ70000.1 AAH21030.1 CAH10482.1 AAH84537.1 BAD96222.1 BAG62619.1 BAG62730.1 BAG59159.1 BAG60039.1 | Q9BVJ8 P06865 | 2GJX 2GK1 | A A |
| Last update: 2008 Dec 17 © Copyright 1998-2008 AFMB - CNRS - Universités Aix-Marseille I & II |