CAZy ~ Carbohydrate-Active enZymes


   
Carbohydrate-Binding Module Family 2
  
Known ActivitiesModules of approx. 100 residues and which are found in a large number of bacterial enzymes. The cellulose-binding function has been demonstrated in many cases. Several of these modules have been shown to also bind chitin or xylan.
 
3D Structure StatusFold: -sandwich
 
NotePreviously known as cellulose-binding domain family II (CBD II).
 
Relevant LinksHOMSTRAD   InterPro   PFAM   PROSITE   
 
StatisticsCAZy Entries (329);  GenBank/GenPept (467);  Uniprot (107);  3D(3) : PDB(9);
 
TaxonomyArchaea(2);  Bacteria(300);  Eukaryota(20);  Viruses(7);  
 
3D DisplayCBM2_3D
 
        
        Archaea          
ProteinEC#OrganismGenBank/GenPeptUniProtPDB/3D
chitinase (PF1233;ChiB) - Chi18B3.2.1.14
Pyrococcus furiosus DSM 3638AE010230
NC_003413
AAL81357.1
NP_578962.1
Q8U1H5
2CWR
[A]
chitinase A (TK1765) 3.2.1.14
Thermococcus kodakaraensis KOD1AP006878
BAD85954.1
Q9UWR7
  
 
        
        Bacteria          
ProteinEC#OrganismGenBank/GenPeptUniProtPDB/3D
endoglucanase (GuxA) 3.2.1.4
Acidothermus cellulolyticus-
-
-
-
-
-
-
-
ABH87623.1
ABH87626.1
ABH87625.1
ABH87627.1
ABH87628.1
ABH87629.1
ABH87630.1
ABH87635.1
   
-mannanase (ManA) n.d.Acidothermus cellulolyticus-
-
-
-
-
ABJ41265.1
ABJ41262.1
ABJ41264.1
ABJ41266.1
ABJ41263.1
   
Acel_0616 n.d.Acidothermus cellulolyticus 11B; ATCC 43068CP000481
ABK52389.1
   
Acel_0970 n.d.Acidothermus cellulolyticus 11B; ATCC 43068CP000481
ABK52743.1
   
Acel_0618 n.d.Acidothermus cellulolyticus 11B; ATCC 43068CP000481
-
-
-
ABK52391.1
ACE14916.1
ACE14917.1
ACE14920.1
   
Acel_0615 n.d.Acidothermus cellulolyticus 11B; ATCC 43068CP000481
ABK52388.1
   
Acel_0179 n.d.Acidothermus cellulolyticus 11B; ATCC 43068CP000481
ABK51954.1
   
Acel_1701 n.d.Acidothermus cellulolyticus 11B; ATCC 43068CP000481
ABK53473.1
   
Acel_0619 n.d.Acidothermus cellulolyticus 11B; ATCC 43068CP000481
ABK52392.1
   
Acel_0617 n.d.Acidothermus cellulolyticus 11B; ATCC 43068CP000481
ABK52390.1
   
endo-1,4-glucanase E1 (Acel_0614) - Cel5A3.2.1.4
Acidothermus cellulolyticus 11B; ATCC 43068U33212
-
CP000481
AX467594
AAA75477.1
ABH84883.1
ABK52387.1
CAD42489.1
P54583
  
Acel_0180 n.d.Acidothermus cellulolyticus 11B; ATCC 43068CP000481
ABK51955.1
   
Aave_2102 n.d.Acidovorax avenae subsp. citrulli AAC00-1CP000512
ABM32683.1
   
Aave_3396 n.d.Acidovorax avenae subsp. citrulli AAC00-1CP000512
ABM33954.1
   
ORF10 n.d.Actinomadura sp. ATCC 39727AJ561198
CAD91236.1
Q7WZ50
  
endo-1,4-glucanase 3.2.1.4
Actinomyces sp. 40U94825
AAC06196.1
O66064
  
Sequence 21 from patent US 7094588 n.d.Actinomycete 11AG8-
ABJ29232.1
   
Tei4 n.d.Actinoplanes teichomyceticus ATCC31131AJ605139
CAE53336.1
   
PCZA361.11 (putative oxidoreductase) n.d.Amycolatopsis orientalisAJ223998
CAA11769.1
O52799
  
endoglucanase (Egl;AZC_1301) n.d.Azorhizobium caulinodans ORS 571AP009384
BAF87299.1
   
BA_0961 n.d.Bacillus anthracis str. A2012NC_003995
NP_654321.1
   
BA0385 (chitinase B) n.d.Bacillus anthracis str. AmesAE017025
NC_003997
AAP24415.1
NP_842929.1
Q81Z87
  
GBAA0385 n.d.Bacillus anthracis str. Ames 0581AE017334
AAT29480.1
   
BAS0371 n.d.Bacillus anthracis str. SterneAE017225
AAT52702.1
   
chitinase CW (ChiCW) 3.2.1.14
Bacillus cereus 28-9AF416570
AAM48520.2
Q8KVU8
  
BCE0497 n.d.Bacillus cereus ATCC 10987AE017265
NC_003909
AAS39432.1
NP_976824.1
   
endochitinase (BC0429) n.d.Bacillus cereus ATCC 14579AE016999
NC_004722
AAP07469.1
NP_830268.1
Q81IF9
  
chitinase B 3.2.1.14
Bacillus cereus CHAB041932
BAB16891.1
Q9FAC8
  
Bcer98_0373 n.d.Bacillus cereus subsp. cytotoxis NVH 391-98CP000764
ABS20731.1
   
BTZK0359 (ChiA) 3.2.1.14
Bacillus cereus ZKCP000001
AAU19880.1
   
chitinase (Chi80) n.d.Bacillus ehimensis EAG3AB110082
BAC76694.1
Q7X5L8
  
chitinase (Chi74) n.d.Bacillus thuringiensisEF197878
ABM66446.1
   
chitinase 3.2.1.14
Bacillus thuringiensis 97243-1EU373094
ACA34287.1
   
chitinase (ChI) n.d.Bacillus thuringiensis BT-7216EF211999
ABO63962.1
   
chitinase (ChiA19) n.d.Bacillus thuringiensis KR 19-22EU557354
ACB59262.1
   
chitinase (Chi) 3.2.1.14
Bacillus thuringiensis LBIT-82AF424979
AY074882
EF427670
AAL17867.1
AAL71886.2
ABO21095.1
Q93AD3
Q8RSX8
  
chitinase n.d.Bacillus thuringiensis serovar alesti HD16AY452507
AAR19092.1
   
chitinase n.d.Bacillus thuringiensis serovar canadensis HD224AY455290
AAR21234.1
   
chitinase (ChiB) n.d.Bacillus thuringiensis serovar colmeri 15A3DQ512474
ABF57674.1
   
chitinase n.d.Bacillus thuringiensis serovar entomocidus HD109AY456381
AAR19226.1
   
chitinase n.d.Bacillus thuringiensis serovar israelensisAF526379
AAM88400.1
Q8KRQ5
  
BT9727_0362 (ChiA) n.d.Bacillus thuringiensis serovar konkukian str. 97-27AE017355
AAT60699.1
   
chitinase (Schi;Kchi) 3.2.1.14
Bacillus thuringiensis serovar kurstakiAY189740
AAO34713.1
Q84FN2
  
chitobiosidase (exochitinase) (chi255) 3.2.1.-

3.2.1.14		Bacillus thuringiensis serovar kurstaki BUPM255AJ635226
CAG25670.1
   
chitinase (ChiA;ChiA-HD73) 3.2.1.14
Bacillus thuringiensis serovar kurstaki HD-73EF581163
ABQ65137.2
   
endochitinase n.d.Bacillus thuringiensis serovar morrisoniDQ993175
ABJ55984.1
   
chitinase n.d.Bacillus thuringiensis serovar sottoAY129671
AAM94024.1
Q8KNY3
  
chitinase n.d.Bacillus thuringiensis serovar toumanoffi HD201AY452506
AAR19091.1
   
BALH_0385 n.d.Bacillus thuringiensis str. Al HakamCP000485
ABK83784.1
   
chitinase (Chi) 3.2.1.14
Bacillus thuringiensis subsp. pakistaniU89796
AAB58579.1
O07088
  
BcerKBAB4_0366 n.d.Bacillus weihenstephanensis KBAB4CP000903
ABY41632.1
   
endo-1,4-glucanase 1 (End1) 3.2.1.4
Butyrivibrio fibrisolvens H17c-
X17538
AAE29745
CAA35574.1
P20847
  
endo-1,4-glucanase B (CenB) - Cel9A3.2.1.4
Cellulomonas fimiM64644
AAA23086.1
P26225
  
cellobiohydrolase B (CbhB;CenE) - Cel48A3.2.1.91
Cellulomonas fimiL29042
L38827
AAA50257.1
AAB00822.1
P50899
  
cellobiohydrolase A (CbhA) - Cel6B3.2.1.91
Cellulomonas fimiL25809
-
AAC36898.1
ABH87631.1
P50401
  
endo-1,4-glucanase D (CenD) - Cel5A3.2.1.4
Cellulomonas fimiL02544
AAA23089.1
P50400
  
endo-1,4-glucanase A (CenA) - Cel6A3.2.1.4
Cellulomonas fimiM15823
-
AAA23084.1
AAE59939.1
P07984
  
xylanase D (XynD;XylD) - Xyn11A3.2.1.8

3.1.1.72		Cellulomonas fimi 221X76729
CAA54145.1
P54865
1E5B
1E5C
1HEH
1HEJ
1XBD
2XBD
[A]
[A]
[C]
[C]
 
 
xylanase B (Cex;XynB) - Xyn10A3.2.1.8
Cellulomonas fimi ATCC 484M15824
L11080
-
AAA56791.1
AAA56792.1
AAB34464.1
P07986
Q59277
1EXG
1EXH
 
 
-1,4-xylanase (Cfx) 3.2.1.8
Cellulomonas fimi ATCC 484DQ146941
AAZ76373.1
   
chitinase (chiXVIIIA) (fragment) n.d.Cellulomonas flavigenaAM292656
CAL23808.1
   
xylanase (XIB;XylXib) n.d.Cellulomonas flavigena CDBB-531AM182259
CAJ57849.1
   
endo-1,4--xylanase (XynI) (fragment) n.d.Cellulomonas flavigena CDBB-531AJ781485
CAH03685.3
   
endo-1,4-glucanase B (CelB;CflB;CelCflB;SP18) 3.2.1.4
Cellulomonas flavigena CDBB-531AF172345
AAD48494.2
Q9S3V3
  
endoglucanase (CBP105) (processive) 3.2.1.4
Cellulomonas flavigena CDBB-531AY729806
AAW62376.2
   
xylanase (XynCflA) (fragment) 3.2.1.8
Cellulomonas flavigena CDBB-5321AF338352
AAK15536.1
Q9AG99
  
xylanase - Xyn11A3.2.1.8
Cellulomonas pachnodaeAF120156
AAD54767.1
Q9RQB8
  
chitinase 63 (Chi63) 3.2.1.14
Cellulomonas sp. GM13AF181718
AAF00931.2
Q84BN2
  
chitinase A (ChiA) 3.2.1.14
Cellulomonas uda ATCC 21399AY008839
AAG27061.2
Q9EY44
  
xylanase B (XynB) 3.2.1.8
Cellvibrio japonicus (formerly Pseudomonas cellulosa)X54523
CAA38389.1
P23030
  
esterase D (XynD) n.d.Cellvibrio japonicus (formerly Pseudomonas cellulosa)X58956
CAA41727.1
Q51815
  
endo-1,4-glucanase A (CelA) 3.2.1.4
Cellvibrio japonicus (formerly Pseudomonas cellulosa)X12570
CAA31082.1
P10476
  
rhamnogalacturonan lyase - Rgl11A4.2.2.-
Cellvibrio japonicus (formerly Pseudomonas cellulosa)AY026755
AAK20911.1
Q9AF09
  
arabinofuranosidase C (XynC) - Abf62A3.2.1.55
Cellvibrio japonicus (formerly Pseudomonas cellulosa)X54523
CAA38390.1
P23031
  
pectate lyase (PelA) - Pel10A4.2.2.2
Cellvibrio japonicus (formerly Pseudomonas cellulosa)AF279264
AAG29353.1
Q9F7L3
  
xylanase A (XynA) - Xyn10A3.2.1.8
Cellvibrio japonicus (formerly Pseudomonas cellulosa)X15429
CAA33469.1
P14768
  
endo--1,4-mannanase 5B - Man5Bn.d.Cellvibrio japonicus (formerly Pseudomonas cellulosa)AY187032
AAO31760.1
Q840C1
  
endo-1,4-glucanase B (CelB) 3.2.1.4
Cellvibrio japonicus (formerly Pseudomonas cellulosa)X52615
CAA36844.1
P18126
  
cellodextrinase C (CelC) 3.2.1.-
Cellvibrio japonicus (formerly Pseudomonas cellulosa)X61299
CAA43597.1
P27033
  
endo-1,4-glucanase E (CelE) 3.2.1.4
Cellvibrio japonicus (formerly Pseudomonas cellulosa)X86798
CAA60493.1
Q59665
  
CJA_2475 - Man5B3.2.1.78
Cellvibrio japonicus Ueda107CP000934
ACE84941.1
   
CJA_1462 (cellodextrinase) - Cel5A3.2.1.-
Cellvibrio japonicus Ueda107CP000934
ACE82870.1
   
CJA_2616 (Cbp2D) n.d.Cellvibrio japonicus Ueda107CP000934
ACE86341.1
   
CJA_3286 - Ebg98n.d.Cellvibrio japonicus Ueda107CP000934
ACE84677.1
   
CJA_3104 (pectate lyase) - Pel10A4.2.2.2
Cellvibrio japonicus Ueda107CP000934.1
ACE85516.1
   
CJA_2473 - Cel6An.d.Cellvibrio japonicus Ueda107CP000934
ACE85978.1
   
CJA_3337 - Cel5En.d.Cellvibrio japonicus Ueda107CP000934
ACE83841.1
   
CJA_2472 (endoglucanase) - Cel9A3.2.1.4
Cellvibrio japonicus Ueda107CP000934.1
ACE85757.1
   
CJA_3281 (-L-arabinofuranosidase) - Abf62A3.2.1.55
Cellvibrio japonicus Ueda107CP000934
ACE85320.1
   
CJA_0007 - Cbp2An.d.Cellvibrio japonicus Ueda107CP000934
ACE83535.1
   
CJA_2983 (endoglucanase) - Cel5B3.4.1.4
Cellvibrio japonicus Ueda107CP000934.1
ACE84076.1
   
CJA_3287 - Fee1An.d.Cellvibrio japonicus Ueda107CP000934
ACE85216.1
   
CJA_3107 - Cbp2Cn.d.Cellvibrio japonicus Ueda107CP000934
ACE82894.1
   
CJA_2477 - Gly74An.d.Cellvibrio japonicus Ueda107CP000934
ACE84745.1
   
CJA_0374 (endoglucanase) - Cel45A3.2.1.4
Cellvibrio japonicus Ueda107CP000934.1
ACE82688.1
   
CJA_2469 - Cbp2Fn.d.Cellvibrio japonicus Ueda107CP000934
ACE86181.1
   
CJA_3280 (xylanase) - Xyn10B3.2.1.8
Cellvibrio japonicus Ueda107CP000934
ACE84499.1
   
CJA_2471 (xylanase) - Xyn10An.d.Cellvibrio japonicus Ueda107CP000934.1
ACE85439.1
 
CJA_3282 - Fee1Bn.d.Cellvibrio japonicus Ueda107CP000934
ACE85652.1
   
CJA_3106 - Cbp2Bn.d.Cellvibrio japonicus Ueda107CP000934
ACE83838.1
   
CJA_3559 (rhamnogalacturonan lyase) - Rgl11A4.2.2.-
Cellvibrio japonicus Ueda107CP000934.1
ACE83155.1
   
CJA_2615 - Cbp2En.d.Cellvibrio japonicus Ueda107CP000934
ACE85262.1
   
CJA_3279 - Xyn5An.d.Cellvibrio japonicus Ueda107CP000934
ACE83181.1
   
CMM_2443 n.d.Clavibacter michiganensis subsp. michiganensis NCPPB 382AM711867
CAN02524.1
   
cellulase (CelA;pCM1_0020) 3.2.1.4
Clavibacter michiganensis subsp. michiganensis NCPPB 382X62582
AM711865
CAA44467.2
CAM98473.1
Q9K5C7
  
cellulase (CelA) 3.2.1.4
Clavibacter michiganensis subsp. sepedonicusAY007311
AAK16222.1
Q9AF65
  
pCS0061 n.d.Clavibacter michiganensis subsp. sepedonicus ATCC33113AM849035
CAQ03244.1
   
endo-1,4-glucanase / xylanase D (EngD) 3.2.1.4

3.2.1.8

3.2.1.73		Clostridium cellulovoransM37434
AAA23233.1
P28623
  
endo-1,4-glucanase (CelA) 3.2.1.4
Clostridium longisporumL02868
AAC37035.1
P54937
  
Cphy_3202 n.d.Clostridium phytofermentans ISDgCP000885
ABX43556.1
   
DSY4481 n.d.Desulfitobacterium hafniense Y51