CAZy ~ Carbohydrate-Active enZymes


   
Carbohydrate-Binding Module Family 1
  
Known ActivitiesModules of approx. 40 residues found almost exclusively in fungi. The cellulose-binding function has been demonstrated in many cases, and appears to be mediated by three aromatic residues separated by about 10.4 angstrom and which form a flat surface. The only non-fungal occurence of CBM1 is in an algal non-hydrolytic polysaccharide-binding protein which is composed of four repeated CBM1 modules. Binding to chitin has been demonstrated in one case.
 
NotePreviously known as cellulose-binding domain family I (CBD I).
 
Relevant LinksInterPro   PFAM   PROSITE   SMART   
 
StatisticsCAZy Entries (290);  GenBank/GenPept (621);  Swissprot (116);  3D(3) : PDB(11); cryst(1);
 
TaxonomyEukaryota(287);  Viruses(1);  unclassified(2);  
 
3D DisplayCBM1_3D
 
        
        Eukaryota          
ProteinEC#OrganismGenBank/GenPeptUniProtPDB/3D
cellobiohydrolase II (Acc2) 3.2.1.91
Acremonium cellulolyticus Y-94-
AB022429
AAE50824
BAA74458.1
O93837
  
Sequence 10 from patent US 6855531 n.d.Acremonium sp.-
AAY00848.1
   
Sequence 8 from patent US 6855531 n.d.Acremonium sp.-
AAY00847.1
   
unnamed protein product n.d.Acremonium thermophilumAX657569
CAD79778.1
   
Sequence 6 from patent US 7361487 n.d.Acremonium thermophilum-
ACE10216.1
   
cellobiohydrolase - Cel7A3.2.1.-
Acremonium thermophilum ALKO4245AM711860
CAM98445.1
   
-mannanase (Cel4A) 3.2.1.78
Agaricus bisporus C54-carb8-
AJ271862
ABJ41267.1
CAB76904.1
Q9P893
  
Cel1 n.d.Agaricus bisporus D649M86356
AAA53434.1
Q00023
  
cellobiohydrolase I (Cel2) 3.2.1.-
Agaricus bisporus D649Z50094
CAA90422.1
Q92400
  
-mannanase (Cel4) 3.2.1.78
Agaricus bisporus D649Z50095
CAA90423.1
Q92401
  
Cel6 n.d.Agaricus bisporus D649AJ292929
AJ534359
CAC02964.1
CAD58875.1
Q9P4T8
Q8J1H7
  
cellobiohydrolase II (Cel3;Cel3A) 3.2.1.91
Agaricus bisporus D649L24519
L24520
-
Z34007
AAA50607.1
AAA50608.1
AAE59938.1
CAA83971.1
P49075
  
endoxylanase F1 (AaF1) n.d.Alternaria alternataAF176570
AAF05698.1
Q9UVP5
  
-mannanase (PM) 3.2.1.78
Armillariella tabescensDQ286392
ABB88954.1
   
FII-CMCase (FII CM-cellulase) 3.2.1.4
Aspergillus aculeatusAB015510
BAA29030.1
O74169
  
avicelase III (AviIII;FIII Avicelase) 3.2.1.4
Aspergillus aculeatus-
AB015511
ACE14921.1
BAA29031.1
O74170
  
xylanase II 3.2.1.8
Aspergillus aculeatusAAC12003
-
AAE69552
CQ945932
AAC12003.1
AAE62343.1
AAE69552.1
CAI29149.1
   
cellobiohydrolase I / chitosanase (CBHI) 3.2.1.-

3.2.1.132		Aspergillus aculeatus F-50AB002821
BAA25183.1
O59843
  
endo--1,4-mannanase (Man I;Man II;AFUA_8G07030;Afu8g07030) 3.2.1.78
Aspergillus fumigatus Af293AAHF01000013
EAL85463.1
   
endoglucanase A (EglA) - Cel5A3.2.1.4
Aspergillus kawachiiAB055431
BAB62317.1
Q96WR0
  
endoglucanase B (EglB) - Cel61A3.2.1.4
Aspergillus kawachiiAB055432
BAB62318.1
Q96WQ9
  
endo--1,4-glucanase (AN1602.2) 3.2.1.4
Aspergillus nidulans FGSC A4DQ490474
AACD01000026
ABF50850.1
EAA64722.1
   
cellobiohydrolase (CbhB;AN0494.2) 3.2.1.-
Aspergillus nidulans FGSC A4AACD01000007
EAA66593.1
   
AN5061.2 n.d.Aspergillus nidulans FGSC A4AACD01000085
EAA60055.1
   
AN9524.2 n.d.Aspergillus nidulans FGSC A4AACD01000231
EAA66740.1
   
AN9276.2 n.d.Aspergillus nidulans FGSC A4AACD01000172
EAA66343.1
   
AN7401.2 n.d.Aspergillus nidulans FGSC A4AACD01000128
EAA61772.1
   
cellobiohydrolase (AN5282.2) 3.2.1.91
Aspergillus nidulans FGSC A4DQ490497
AACD01000093
ABF50873.1
EAA62442.1
   
xyloglucanase C (EglC) 3.2.1.151
Aspergillus nigerAY040839
AAK77227.1
Q8TFP1
  
An12g02220 n.d.Aspergillus niger CBS 513.88AM270264
CAK41068.1
   
cellobiohydrolase B (CbhB;An01g11660) 3.2.1.-
Aspergillus niger CBS 513.88AF156269
-
AM269981
CS475859
AAF04492.1
AAP66264.1
CAK44068.1
CAM35324.1
Q9UVS8
  
An15g04900 n.d.Aspergillus niger CBS 513.88AM270345
CAK42466.1
   
An14g02670 n.d.Aspergillus niger CBS 513.88AM270318
CAK46515.1
   
An01g11670 n.d.Aspergillus niger CBS 513.88AM269981
CAK44069.1
   
An01g01870 (EglC) n.d.Aspergillus niger CBS 513.88AM269954
CAK43558.1
   
An16g06800 n.d.Aspergillus niger CBS 513.88AM270373
CAK42930.1
   
An15g04570 n.d.Aspergillus niger CBS 513.88AM270343
CAK97324.1
   
AO090011000715 n.d.Aspergillus oryzae RIB 40AP007171
BAE65168.1
   
AO090103000087 n.d.Aspergillus oryzae RIB 40AP007174
BAE65561.1
   
AO090005000531 n.d.Aspergillus oryzae RIB 40AP007151
BAE55582.1
   
cellobiohydrolase (Cbh-1) n.d.Athelia rolfsiiAB103461
BAC81967.1
   
unnamed protein product (splicing problem) n.d.Botryosphaeria rhodinaCS272684
CAJ81210.1
   
unnamed protein product n.d.Chaetomidium pingtungiumAX657623
CAD79795.1
   
unnamed protein product n.d.Chaetomium thermophilumAX657571
CAD79779.1
   
unnamed protein product n.d.Chaetomium thermophilumCQ838150
CAH05669.1
   
cellobiohydrolase - Cel7A3.2.1.-
Chaetomium thermophilum ALKO4265AM711862
-
CAM98448.1
ACE10217.1
   
cellobiohydrolase (Cbh1) n.d.Chaetomium thermophilum CT2AY861347
AAW64926.1
   
cellobiohydrolase (Cbh2) 3.2.1.91
Chaetomium thermophilum CT2AY861348
DQ020255
AAW64927.1
AAY88915.1
   
CBHI (fragment) n.d.Chaetomium thermophilum var. thermophilum DSM1495AY653226
AAT84320.1
   
xylanase F (Xyl1;XylF;Xyll) - Xyn10A3.2.1.8
Chrysosporium lucknowenseAAQ38147
AAQ38147.1
   
xylanase (Xyl3) - Xyn10B3.2.1.8
Chrysosporium lucknowense     
cellobiohydrolase Ia (Cbh1a;CBH I) - Cel7A3.2.1.-
Chrysosporium lucknowense-
AAQ38146.1
   
Cel6 n.d.Cochliobolus heterostrophus C4AY116306
AAM76663.1
Q8J0H7
  
pectin lyase (Pnl1;Pnl-1) 4.2.2.10
Colletotrichum gloeosporioides f. sp. malvaeAF158256
AAF22244.1
Q9UUS4
  
unnamed protein product n.d.Coniothyrium minitansAX047667
CAC18990.1
   
cellobiose dehydrogenase (Cdh) n.d.Corynascus heterothallicus ATCC42464AF074951
AAC26221.1
O74240
  
cellobiohydrolase (CbhB) 3.2.1.-
Emericella nidulansAF420020
AAM54070.1
Q8NK02
  
unnamed protein product n.d.Exidia glandulosaAX657613
CAD79790.1
   
endoglucanase B n.d.Fusarium oxysporumL29377
-
AAA65585.1
AAE59937.1
P46236
  
cellobiohydrolase I - Cel7An.d.Fusarium oxysporumL29379
AAA93710
AAC10999
EU214547
AAA65587.1
AAA93710.1
AAC10999.1
ABY16672.1
P46238
  
endoglucanase K - Cel45A3.2.1.4
Fusarium oxysporumL29381
-
-
-
CS424318
AAA65589.1
AAN23441.1
AAO30278.1
AAO30280.1
CAL49901.1
P45699
  
cellulase F (CelF) 3.2.1.8
Fusarium oxysporumL29380
AAA65588.1
P46239
  
xylanase 3 (Xyl3) 3.2.1.8
Fusarium oxysporum f. sp. lycopersici 42-87AF052582
AAC06239.1
O59937
  
exoglucanase type C (Cbh-C) n.d.Fusarium poaeAY706934
AF546134
AAX60003.1
AAQ11999.1
   
exoglucanase type C (Cbh-C) n.d.Fusarium venenatum 5AF490895
AY706932
AAN07154.1
AAX60001.1
   
exoglucanase type C (CBH-C) n.d.Gibberella avenaceaAY502071
AAS82857.1
   
exoglucanase type C (CBH-C) n.d.Gibberella pulicaris 2AF490892
AY502072
AY706931
EU214558
AAN07151.1
AAS82858.1
AAX60000.1
ABY16678.1
   
Xyl16 n.d.Gibberella zeaeAY648859
AAV66343.1
   
Xyl21 n.d.Gibberella zeae F4AY575964
AAT84257.1
   
cellobiohydrolase C (Cel7) - Cel7An.d.Gibberella zeae K59AY196784
AY196784
AY342396
AY706933
AAO42612.1
AAO42612.2
AAR02398.1
AAX60002.1
   
endoglucanase Cel45 - Cel45n.d.Gibberella zeae K59AY342397
AAR02399.1
   
Cel6 - Cel6n.d.Gibberella zeae K59AY302753
AY336127
AAQ72468.1
AAR01213.1
   
ORF (fragment) n.d.Griffithsia japonicaAY123116
AAM93988.1
Q7XZ36
  
ORF (fragment) n.d.Griffithsia japonicaAY123124
AAM93996.1
Q7XZ28
  
ORF (fragment) n.d.Griffithsia japonicaAY123106
AAM93978.1
Q7XZ46
  
cellobiohydrolase (Cbh-1) 3.2.1.-
Humicola grisea var. thermoidea IFO9854D63515
BAA09785.1
Q12621
  
cellobiohydrolase I (Cbh1.1;Cbh1) - Cel7A3.2.1.-
Humicola grisea var. thermoideaX17258
CAA35159.1
P15828
  
endo-1,4-glucanase (Egl3) 3.2.1.4
Humicola grisea var. thermoidea-
-
AB003107
AAE55435.1
AAN19009.1
BAA74956.1
O93782
  
xylanase I (Xyn1;Xyl1) 3.2.1.8
Humicola grisea var. thermoidea IFO9854AB001030
BAA19220.1
P79046
  
endo-1,4-glucanase 3 (CMC3;Egl2) 3.2.1.4
Humicola grisea var. thermoidea IFO9854D84470
BAA12676.1
Q12620
  
endo-1,4-glucanase IV (CMC3) 3.2.1.4
Humicola insolensX76046
CAA53631.1
Q12624
Q12620
  
unnamed protein product n.d.Humicola insolensCQ799078
CAG27577.1
   
avicelase 2 (Avi2) n.d.Humicola insolens
AB048710
AAN19008.1
BAB39154.1
Q9C1S9
  
endo-1,4-glucanase V (EG V) - Cel45A3.2.1.4
Humicola insolens DSM 1800



-
-
ABA35703
-
A21793
A23635
A23644
A23953
A23957
A68060
CS135949
AAE16508
AAN23440.1
AAO30277.1
AAO30279.1
AAX00991.1
AAY74558.1
ABA35703.1
ABN29330.1
CAA01574.1
CAA01681.1
CAA01683.1
CAA01696.1
CAA01698.1
CAB42307.1
CAJ21530.1
P43316
  
endo-1,4-glucanase I (EGI;Egl1) - Cel7B3.2.1.4
Hypocrea jecorinaM15665
-
-
-
-
-
AAA34212.1
AAE25071.1
AAQ24882.1
AAR60514.1
ABE22091.1
ABE22093.1
P07981
  
endoglucanase V (EGV) - Cel45A3.2.1.4
Hypocrea jecorinaZ33381
CAA83846.1
P43317
  
endo-1,4-glucanase II (EGII;Egl2) - Cel5A3.2.1.4
Hypocrea jecorinaM19373
-
-
DQ178347
-
-
AAA34213.1
AAQ24883.1
AAR60515.1
ABA64553.1
ABE22092.1
ABE22094.1
P07982
  
cellobiohydrolase I / chitosanase (CBHI;Cbh1) - Cel7A3.2.1.-

3.2.1.132		Hypocrea jecorina L27-
-
CQ757626
CQ757626
CQ757626
CQ757626
AAE25072.1
AAR60512.1
CAF32516.1
CAF32517.1
CAF32518.1
CAH10320.1
P62694
P00725
1AZ6
1AZH
1AZJ
1AZK
1CBH
1EK7
1I5M
2CBH
 
 
 
 
 


 
endo--1,4-glucanase (Egl1) 3.2.1.4
Hypocrea jecorina PTCC 5142AY928809
AAX28897.1
   
xyloglucanase (Egl6) - Cel74A3.2.1.151
Hypocrea jecorina QM6aAY281371
-
-
AAP57752.1
ABH71452.1
ABJ18610.1
Q7Z9M8
  
4-O-methyl-glucuronoyl esterase (Cip2) 3.1.1.-
Hypocrea jecorina QM6aAY281368
AAP57749.1
Q7Z9N1
cryst 
Cip1 n.d.Hypocrea jecorina QM6aAY281370
AAP57751.1
Q7Z9M9
  
cellobiohydrolase II (CBHII;Cbh2) - Cel6A3.2.1.91
Hypocrea jecorina QM9414M16190
M55080
-
AF302657
-
AAA34210.1
AAA72922.1
AAE59936.1
AAG39980.1
AAR60513.1
P07987
Q9HEY8
  
acetyl xylan esterase (Axe1) 3.1.1.72
Hypocrea jecorina RutC-30Z69256
CAA93247.1
Q99034
  
-mannanase - Man5A3.2.1.78
Hypocrea jecorina RutC-30L25310
-
AAA34208.1
ABJ41268.1
Q99036
  
swollenin (Swo1) n.d.Hypocrea jecorina RutC-30-
-
-
-
-
AJ245918
AAN93048.1
AAN93050.1
AAN93065.1
ABC14974.1
ABC14975.1
CAB92328.1
Q9P8D0
  
endo-1,4-glucanase IV (EGIV;Egl4) - Cel61A3.2.1.4
Hypocrea jecorina RutC-30Y11113
CAA71999.1
O14405
  
cellobiohydrolase II (Cbh2) 3.2.1.91
Hypocrea koningiiAF315681
AAK01367.1
   
cellobiohydrolase II (Cbh2;CbhII) n.d.Hypocrea koningii 3.2774DQ504304
ABF56208.1
   
cbh2 n.d.Hypocrea koningii AS3.2774DQ660372
ABG48766.1
   
cellobiohydrolase (Cbh1) - Cel7A3.2.1.-
Hypocrea koningii G-39X69976
CAA49596.1
P62695
P00725
  
cellobiohydrolase (Cbh1)