Polysaccharide Lyase Family 8

Activities in Familyhyaluronate lyase (EC 4.2.2.1); chondroitin AC lyase (EC 4.2.2.5); xanthan lyase (EC 4.2.2.12); chondroitin ABC lyase (EC 4.2.2.20)
3D Structure Status( α / α ) 6 barrel + anti-parallel β-sheet
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (1702); Uniprot accession (198); PDB accession (44); 3D entries (9); cryst (1)
All (1623) Archaea (1) Bacteria (1619) Eukaryota (3) Structure (9 - 1 cryst) Characterized (27)
| 1 | ... | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | ... | 17 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 QMA0248_0228 (HylB)   Streptococcus iniae QMA0248 ASL34076.1     1
 K710_0217   Streptococcus iniae SF1 AGM98022.1     1
 SI82_01295   Streptococcus iniae YSFST01-82 AJG25283.1     1
 hyaluronate lyase 4.2.2.1 Streptococcus intermedius ATCC 27335 AAK67167.1 Q934I4   1
 SIR_1547   Streptococcus intermedius B196 AGU76898.1     1
 SII_1533   Streptococcus intermedius C270 AGU78697.1     1
 A6J72_07395   Streptococcus intermedius FDAARGOS_233 ARC27012.1     1
 SCIM_1362   Streptococcus intermedius JTH08 BAM24016.1     1
 RN88_07180   Streptococcus intermedius KCOM 1545 ALF28283.1     1
 NCTC11324_01543   Streptococcus intermedius NCTC11324 SQH52493.1     1
 SITYG_16360   Streptococcus intermedius TYG1620 BAW17615.1     1
 SAMEA4412692_01386 (HylA)   Streptococcus merionis NCTC13788 SNU89167.1     1
 STP_1167   Streptococcus parauberis KCTC 11537 AEF25615.1     1
 Sequence 4843 from patent US 6800744   Streptococcus pneumoniae AAW09447.1
ABI03997.1
ABI09038.1
ABJ32554.1
ABJ50167.1
ABL17910.1
    1
 BUM80_10710   Streptococcus pneumoniae 11A AUC46739.1     1
 CWI64_08655   Streptococcus pneumoniae 19F AUB33652.1     1
 C4N11_01535   Streptococcus pneumoniae 335 AVD74319.1     1
 SP670_0382   Streptococcus pneumoniae 670-6B ADM90457.1 E0TRJ4   1
 SP70585_0379   Streptococcus pneumoniae 70585 ACO16655.1 C1CB94   1
 T308_01575   Streptococcus pneumoniae A026 AGZ47134.1     1
 A66_00307   Streptococcus pneumoniae A66 CRI61018.1     1
 SPAP_0347   Streptococcus pneumoniae AP200 ADM83940.1 E0SVG1   1
 SPN23F02890   Streptococcus pneumoniae ATCC 700669 CAR68147.1 B8ZL35   1
 SPCG_0322   Streptococcus pneumoniae CGSP14 ACB89574.1 B2ISN7   1
 DA395_01895   Streptococcus pneumoniae CP2215 AVV90715.1     1
 SPND122_00329 (fragment)   Streptococcus pneumoniae D122 AOG55280.1     1
 SPND141_00331 (fragment)   Streptococcus pneumoniae D141 AOG57361.1     1
 SPD_0287   Streptococcus pneumoniae D39 ABJ54273.1 Q04ME3   1
 SPV_0287 (SpnhL)   Streptococcus pneumoniae D39V AVN85461.1     1
 C3Y86_01500   Streptococcus pneumoniae EF3030 AXK90819.1     1
 SPG_0285 (HyL)   Streptococcus pneumoniae G54 ACF54992.1 B5E6X4   1
 HMPREF1038_00364 (HysA)   Streptococcus pneumoniae gamPNI0373 AFS42440.1     1
 SPNHU15_00387   Streptococcus pneumoniae Hu15 ARD36199.1     1
 SPNHU17_00385   Streptococcus pneumoniae Hu17 ARD33999.1     1
 SPH_0426   Streptococcus pneumoniae Hungary19A-6 ACA36441.1 B1I936   1
 INV104_02610   Streptococcus pneumoniae INV104 CBW35945.1 E1XPE8   1
 SPNINV200_02820   Streptococcus pneumoniae INV200 CBW33916.1 E1XHX5   1
 SPJ_0310   Streptococcus pneumoniae JJA ACO18875.1 C1CC91   1
 KK0381_20060 (fragment)   Streptococcus pneumoniae KK0381 BAX32126.1     1
 KK0981_23420 (fragment)   Streptococcus pneumoniae KK0981 BAW83838.1     1
 KK1157_21240 (fragment)   Streptococcus pneumoniae KK1157 BAX34421.1     1
 MDRSPN_00289 (HysA)   Streptococcus pneumoniae MDRSPN001 BBA58495.1     1
 NCTC11902_00321   Streptococcus pneumoniae NCTC11902 SQG97959.1     1
 NCTC13276_00295   Streptococcus pneumoniae NCTC13276 SQG33576.1     1
 ERS445053_00184   Streptococcus pneumoniae NCTC7465 COT00131.1     1
 NCTC7466_00296   Streptococcus pneumoniae NCTC7466 SQG01354.1     1
 SpnNT_00308 (fragment)   Streptococcus pneumoniae NT_110_58 AJD71249.1     1
 SPP_0350   Streptococcus pneumoniae P1031 ACO21275.1 C1CII1   1
 hyaluronate lyase (HysA) 4.2.2.1 Streptococcus pneumoniae R6 AAK99090.1
AAA53685.1
AAA53686.1
AAT16666.1
ACK14456.1
ACW45175.1
NP_357880.1
Q8CWU3 1C82[A]
1EGU[A]
1F9G[A]
1LOH[A]
1LXK[A]
1N7N[A]
1N7O[A]
1N7P[A]
1N7Q[A]
1N7R[A]
1OJM[A]
1OJN[A]
1OJO[A]
1OJP[A]
1W3Y[A]
2BRP[A]
2BRV[X]
2BRW[A,B]
1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP004 AGI41259.1     1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP008 AGI41260.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP010 AGI41261.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP014 AGI41262.1     1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP015 AGI41263.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP017 AGI41264.1     1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP028 AGI41265.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP031 AGI41266.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP034 AGI41267.1     1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP035 AGI41268.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP036 AGI41269.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP037 AGI41270.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP038 AGI41271.1     1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP039 AGI41272.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP041 AGI41273.1     1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP043 AGI41274.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP044 AGI41275.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP066 AGI41276.1     1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP072 AGI41277.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP074 AGI41278.1     1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP089 AGI41279.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP090 AGI41280.1     1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP091 AGI41281.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP092 AGI41282.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP094 AGI41283.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP096 AGI41284.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP098 AGI41285.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP100 AGI41286.1     1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP102 AGI41287.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP103 AGI41288.1     1
 BMJ42_00426   Streptococcus pneumoniae SP49 APJ29761.1     1
 BOC71_00314 (fragment)   Streptococcus pneumoniae SP61 APJ31834.1     1
 BOC72_00314 (fragment)   Streptococcus pneumoniae SP64 APJ33859.1     1
 C1H54_01650   Streptococcus pneumoniae SPN XDR SMC1710-32 AXJ87751.1     1
 SPNA45_01722   Streptococcus pneumoniae SPNA45 CCM09007.1     1
 MYY_0397   Streptococcus pneumoniae ST556 AFC94059.1     1
 SPT_0364   Streptococcus pneumoniae Taiwan19F-14 ACO22630.1 C1CPJ1   1
 HMPREF0837_10617 (fragment)   Streptococcus pneumoniae TCH8431/19A ADI68845.1 D6ZQF6   1
 hyaluronate lyase (Hyl;SpHyl;SP0314) 4.2.2.1 Streptococcus pneumoniae TIGR4 AAK74491.1
NP_344851.1
Q54873   1
 CXP32_01570   Streptococcus pneumoniae Xen35 AUF84202.1     1
 hyaluronate lyase (HylA) 4.2.2.1 Streptococcus pyogenes AAF29533.1 Q9L7W9   1
 HylA   Streptococcus pyogenes 1020 ABU63951.1 A7XFV6   1
 HylA   Streptococcus pyogenes 1055 ABU63942.1 A7XFU7   1
 C7K40_04130   Streptococcus pyogenes 14GA0832 AXI57898.1     1
 STAB904_04685   Streptococcus pyogenes 1E1 AIW11723.1     1
 HylA   Streptococcus pyogenes 2397 ABU63950.1 A7XFV5   1
 HylA   Streptococcus pyogenes 3200 ABU63939.1 A7XFU4   1
 HylA   Streptococcus pyogenes 350 ABU63943.1 A7XFU8   1
 HylA   Streptococcus pyogenes 3779 ABU63952.1 A7XFV7   1
 HylA   Streptococcus pyogenes 422 ABU63944.1 A7XFU9   1
 HylA   Streptococcus pyogenes 4282 ABU63947.1 A7XFV2   1
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