Polysaccharide Lyase Family 8

Activities in Familyhyaluronate lyase (EC 4.2.2.1); chondroitin AC lyase (EC 4.2.2.5); xanthan lyase (EC 4.2.2.12); chondroitin ABC lyase (EC 4.2.2.20)
3D Structure Status( α / α ) 6 barrel + anti-parallel β-sheet
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (1262); Uniprot accession (198); PDB accession (44); 3D entries (9); cryst (1)
All (1182) Archaea (1) Bacteria (1179) Eukaryota (2) Structure (9 - 1 cryst) Characterized (27)
| 1 | 2 |
Archaea
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 Hmuk_3227   Halomicrobium mukohataei DSM 12286 ACV49330.1 C7P4T5  
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 SAMN04489717_1639   Actinopolymorpha singaporensis DSM 22024 SDS10494.1    
 SAMN04489717_3547   Actinopolymorpha singaporensis DSM 22024 SDS69346.1    
 SAMN04489717_2056   Actinopolymorpha singaporensis DSM 22024 SDS24044.1    
 Amir_0500 (fragment)   Actinosynnema mirum DSM 43827 ACU34467.1 C6WI16  
 CNX65_02545 (fragment)   Actinosynnema pretiosum X47 ATE52313.1    
 PYTT_0964   Akkermansia glycaniphila SEH81749.1    
 APS56_13715   Algibacter alginicilyticus HZ22 ALJ06121.1     3
 APS56_04640   Algibacter alginicilyticus HZ22 ALJ04469.1     2
 APS56_13745   Algibacter alginicilyticus HZ22 ALJ06125.1     3
 APS56_04620   Algibacter alginicilyticus HZ22 ALJ04465.1     2
 AL1_08200   Alistipes shahii WAL 8301 CBK63375.1 D4IKB3   2
 AL1_00280   Alistipes shahii WAL 8301 CBK62766.1 D4IIK4  
 AL1_08220   Alistipes shahii WAL 8301 CBK63377.1 D4IKB5   2
 SAMN04489726_5005   Allokutzneria albata DSM 44149 SDN11771.1    
 AJAP_14535   Amycolatopsis japonica MG417-CF17 AIG75785.1    
 SAMN04489733_0800   Amycolatopsis keratiniphila FH 1893 SDU06084.1    
 BB31_37720   Amycolatopsis lurida NRRL 2430 AJK58748.1    
 B737_5886   Amycolatopsis mediterranei RB AGT86550.1    
 AMES_5886   Amycolatopsis mediterranei S699 AFO79422.1
AEK44599.1
   
 AMED_5970   Amycolatopsis mediterranei U32 ADJ47711.1 D8HN29  
 SD37_24605   Amycolatopsis orientalis B-37 ANN18491.1    
 AORI_4997   Amycolatopsis orientalis HCCB10007 AGM07581.1    
 MB46_19365   Arthrobacter sp. A3 ALV47837.1    
 AL755_00180   Arthrobacter sp. ERGS1:01 ALE04181.1    
 AL755_04595   Arthrobacter sp. ERGS1:01 ALE04933.1    
 Arth_1698   Arthrobacter sp. FB24 ABK03092.1 A0JVM2  
 chondroitin lyase (Choa1)   Arthrobacter sp. GAG ANC28180.1    
 AHiyo8_07950 (fragment)   Arthrobacter sp. Hiyo8 BAS12492.1    
 chondroitin sulfate lyase (ChoA1)   Arthrobacter sp. MAT3885 AFM38168.1    
 ART_3702   Arthrobacter sp. PAMC 25486 AIY03301.1    
 ART_3703   Arthrobacter sp. PAMC 25486 AIY03302.1     2
 ARUE_c32170   Arthrobacter sp. Rue61a AFR30098.1    
 ARUE_232p01360 (short fragment)   Arthrobacter sp. Rue61a AFR31344.1    
 CGK93_17430   Arthrobacter sp. YN ASN21263.1    
 CY96_17710   Bacillus bombysepticus str. Wang AHX19751.1    
 pE33L466_0352   Bacillus cereus E33L AAY60495.1
AJI26182.1
Q4V1B2  
 heparinase (Hep)   Bacillus circulans BAB91369.1 Q8KKH9   2
 AM592_01170   Bacillus gobiensis FJAT-4402 ALC80364.1    
 hyaluronate lyase (BniHL)   Bacillus niacini F8 BAO57293.1    
 Bsel_0843   [Bacillus] selenitireducens MLS10 ADH98369.1 D6XZJ5  
 hyaluronidase (Hyl;HAase-B) (partial) 4.2.2.1 Bacillus sp. A50 AHB61202.1    
 xanthan lyase (Xly) 4.2.2.12 Bacillus sp. GL1 BAB21059.1 Q9AQS0 1J0M[A]
1J0N[A]
1X1H[A]
1X1I[A]
1X1J[A]
2E22[A]
2E24[A]
 CGC64_05665   Bacteroides caccae ATCC 43185 ASM65495.1     3
 CGC64_15715   Bacteroides caccae ATCC 43185 ASM67245.1    
 CGC64_04155   Bacteroides caccae ATCC 43185 ASM65228.1     2
 CGC64_04295   Bacteroides caccae ATCC 43185 ASM65253.1     2
 A4V03_19125   Bacteroides caecimuris I48 ANU59423.1     2
 A4V03_18910   Bacteroides caecimuris I48 ANU59382.1     2
 BcellWH2_01185 (Csla_2)   Bacteroides cellulosilyticus WH2 ALJ58447.1    
 BcellWH2_03149 (Csla_5)   Bacteroides cellulosilyticus WH2 ALJ60386.1    
 BcellWH2_02521   Bacteroides cellulosilyticus WH2 ALJ59760.1     2
 BcellWH2_03154 (Csla_6)   Bacteroides cellulosilyticus WH2 ALJ60391.1    
 BcellWH2_02528 (ChonabC)   Bacteroides cellulosilyticus WH2 ALJ59767.1     2
 BcellWH2_03147 (Csla_4)   Bacteroides cellulosilyticus WH2 ALJ60384.1    
 BcellWH2_00910 (Csla_1)   Bacteroides cellulosilyticus WH2 ALJ58172.1     3
 BF638R_1599   Bacteroides fragilis 638R CBW22130.1 E1WTQ7  
 MB0529_01465 (CslA)   Bacteroides fragilis BE1 CUA18113.1    
 VU15_06680   Bacteroides fragilis BOB25 AKA51421.1    
 BF1599   Bacteroides fragilis NCTC 9343 CAH07300.1 Q5LEZ9  
 AE940_04150   Bacteroides fragilis S14 ANQ60073.1    
 BF1585   Bacteroides fragilis YCH46 BAD48335.1 Q64VZ1  
 Bache_0583   Bacteroides helcogenes P 36-108 ADV42608.1     2
 Bache_0581   Bacteroides helcogenes P 36-108 ADV42606.1     3
 Bovatus_03480 (Chonabc_2)   Bacteroides ovatus ATCC 8483 ALJ48087.1     2
 Bovatus_03443 (Chonabc_1)   Bacteroides ovatus ATCC 8483 ALJ48050.1     2
 BACOV975_01259   Bacteroides ovatus V975 SCV07496.1     2
 BACOV975_01221   Bacteroides ovatus V975 SCV07458.1     2
 chondroitin sulfate lyase AC (CslA) 4.2.2.5 Bacteroides stercoris HJ-15 ABW87764.1 A9Y5J0   3
 Btheta7330_04950 (Chonabc_1)   Bacteroides thetaiotaomicron 7330 ALJ44464.1     2
 Btheta7330_04976 (Chonabc_2)   Bacteroides thetaiotaomicron 7330 ALJ44490.1     2
 Btheta7330_00132 (CslA)   Bacteroides thetaiotaomicron 7330 ALJ39732.1     3
 BT3324 4.2.2.20 Bacteroides thetaiotaomicron VPI-5482 AAO78430.1
NP_812236.1
Q8A2I1   2
 BT2964   Bacteroides thetaiotaomicron VPI-5482 AAO78070.1
NP_811876.1
Q8A3J0   3
 lyase 2 (CsuB;BT3350)   Bacteroides thetaiotaomicron VPI-5482 AAO78456.1
AAA99039.1
NP_812262.1
Q45773
Q8A2F5
  2
 chondroitin sulfate ABC lyase 4.2.2.20 Bacteroides thetaiotaomicron WAL2926 ABV21364.1 C5G6D7 2Q1F[A,B] 2
 BXY_25910   Bacteroides xylanisolvens XB1A CBK67635.1 D6CZN3   2
 BXY_26470   Bacteroides xylanisolvens XB1A CBK67690.1 D6CZT8   2
 Bcav_0174   Beutenbergia cavernae DSM 12333 ACQ78439.1 C5BVJ9  
 Bcav_4062   Beutenbergia cavernae DSM 12333 ACQ82303.1 C5C5U5  
 CGC63_14875   Blautia hansenii DSM 20583 ASM70662.1    
 CGC63_02885   Blautia hansenii DSM 20583 ASM68536.1    
 CFK38_04965   Brachybacterium sp. VM2412 ATG50954.1    
 CFK38_06655   Brachybacterium sp. VM2412 ATG51240.1    
 CFK39_06120   Brachybacterium sp. VR2415 ASK65477.1    
 X994_6505 (XlY)   Burkholderia pseudomallei sp. TSV202 AIV73723.1    
 ZP_03683870.1   Catenibacterium mitsuokai DSM 15897 ZP_03683870.1 E2NVA0  
 Caci_4980   Catenulispora acidiphila DSM 44928 ACU73840.1 C7Q3A4  
 Caci_6725   Catenulispora acidiphila DSM 44928 ACU75571.1 C7Q078  
 A5M85_07305   Cellulophaga lytica DAU203 APU10096.1    
 CK934_20340   Chitinophaga sp. MD30 ASZ13140.1     3
 COR50_19620   Chitinophagaceae bacterium 13 ATL49204.1    
 COR50_18015   Chitinophagaceae bacterium 13 ATL48910.1     3
 CJF12_04375   Chryseobacterium piperi ATCC BAA-1782 ASW73600.1    
 NPD11_532   Clostridium baratii CDC51267 AQM59403.1    
 U729_2500   Clostridium baratii str. Sullivan AIY84950.1    
 CbC4_2106   Clostridium botulinum BKT015925 AEB76773.1    
 CCH01_11130   Clostridium chauvoei JF4335 SLK16803.1    
 CPF_0394   Clostridium perfringens ATCC 13124 ABG84856.1 Q0TU39  
 JFP55_02345   Clostridium perfringens JP55 AMN31810.1    
 CMR01_13125   Clostridium perfringens LLY_N11 ATD49691.1    
 CPR_0390   Clostridium perfringens SM101 ABG85527.1 Q0SVY1  
 Closa_2597   [Clostridium] saccharolyticum WM1 ADL05163.1 D9R556  
 SAMN02745906_2273   [Clostridium] sphenoides JCM 1415 ATCC 19403 SET83267.1    
 SAMN02745906_1555   [Clostridium] sphenoides JCM 1415 ATCC 19403 SET74231.1    
 ZP_02868286.1   Clostridium spiroforme DSM 1552 ZP_02868286.1 B1C4V9  
 ZP_02866302.1   Clostridium spiroforme DSM 1552 ZP_02866302.1 B1BYS5  
 Ctu_30970   Cronobacter turicensis z3032 CBA32803.1    
 GA0004736_3627   Curtobacterium sp. 9128 SBN64664.1    
 hyaluronate lyase (Hyase) 4.2.2.1 Cutibacterium acnes AAA51650.1 P0CZ00
Q59634
 
 RN83_02370   Cutibacterium acnes KCOM 1861 (= ChDC B594) ALD70665.1    
 ALW29_01905   Cutibacterium acnes PA_12_1_L1 ALT41516.1    
 ALW27_01910   Cutibacterium acnes PA_12_1_R1 ALT39279.1    
 ALW33_02050   Cutibacterium acnes PA_15_1_R1 ALT43803.1    
 ALW23_02060   Cutibacterium acnes PA_15_2_L1 ALT37000.1    
 ALW21_01935   Cutibacterium acnes PA_21_1_L1 ALT36368.1    
 ALW22_01915   Cutibacterium acnes PA_30_2_L1 ALT32426.1    
 BFS79_05010   Cutibacterium avidum DPC 6544 AOG27986.1    
 CA2015_4151   Cyclobacterium amurskyense KCTC 12363 AKP53504.1    
 CA2015_3294   Cyclobacterium amurskyense KCTC 12363 AKP52686.1    
 Cycma_4185   Cyclobacterium marinum DSM 745 AEL27889.1    
 Cycma_3427   Cyclobacterium marinum DSM 745 AEL27150.1    
 SAMN06298216_2863   Cytophagales bacterium TFI 002 SOE22426.1    
 DGI_2110   Desulfovibrio gigas DSM 1382 = ATCC 19364 AGW13874.1    
 Echvi_2165   Echinicola vietnamensis DSM 17526 AGA78416.1     3
 Echvi_2985   Echinicola vietnamensis DSM 17526 AGA79223.1    
 ETEE_1143   Edwardsiella anguillarum ET080813 AIJ07606.1     2
 ETEE_1144   Edwardsiella anguillarum ET080813 AIJ07607.1     2
 A9798_02625   Edwardsiella hoshinae ATCC 35051 AOV95954.1     2
 A9798_02620   Edwardsiella hoshinae ATCC 35051 AOV95953.1     2
 NT01EI_3294   Edwardsiella ictaluri 93-146 ACR70433.1 C5B905   2
 NT01EI_3295   Edwardsiella ictaluri 93-146 ACR70434.1 C5B906   2
 B6E78_08090   Edwardsiella ictaluri RUSVM-1 ARD39341.1     2
 B6E78_08095   Edwardsiella ictaluri RUSVM-1 ARD39342.1     2
 ETAC_14055   Edwardsiella piscicida C07-087 AGH74932.1     2
 ETAC_14050   Edwardsiella piscicida C07-087 AGH74931.1     2
 BXA22_11120   Edwardsiella piscicida ETW41 ARD18852.1     2
 BXA22_11125   Edwardsiella piscicida ETW41 ARD18853.1     2
 A9797_14525   Edwardsiella piscicida S11-285 AOP44139.1     2
 A9797_14520   Edwardsiella piscicida S11-285 AOP44138.1     2
 QY76_05730   Edwardsiella sp. EA181011 AKM46907.1     2
 QY76_05735   Edwardsiella sp. EA181011 AKM46908.1     2
 AAZ33_15510   Edwardsiella sp. LADL05-105 AKR78793.1     2
 ETAE_2917   Edwardsiella tarda EIB202 ACY85750.1 D0ZDX1   2
 ETAE_2918   Edwardsiella tarda EIB202 ACY85751.1 D0ZDX2   2
 ORF   Edwardsiella tarda ET-1 BAU80588.1     2
 ETAF_2650   Edwardsiella tarda FL6-60 ADM42753.1 E0T7G9   2
 ETAF_2651   Edwardsiella tarda FL6-60 ADM42754.1 E0T7H0   2
 AAW15_02425   Edwardsiella tarda FL95-01 AKH88081.1     2
 AAW15_02430   Edwardsiella tarda FL95-01 AKH88082.1     2
 CPU03_10765   Edwardsiella tarda KC-Pc-HB1 ATI64703.1     2
 CPU03_10760   Edwardsiella tarda KC-Pc-HB1 ATI64702.1     2
 BBD28_12310   Elizabethkingia anophelis 0422 AQW91392.1    
 BBD28_12305   Elizabethkingia anophelis 0422 AQW91391.1    
 BBD31_02870   Elizabethkingia anophelis 3375 AQW96894.1    
 BBD31_02865   Elizabethkingia anophelis 3375 AQW96893.1    
 EAAG1_007425   Elizabethkingia anophelis Ag1 ATC39691.1    
 EAAG1_007420   Elizabethkingia anophelis Ag1 ATC39690.1    
 CMV40_07425   Elizabethkingia anophelis AR4-6 ATC47046.1    
 CMV40_07420   Elizabethkingia anophelis AR4-6 ATC47045.1    
 CMV41_07425   Elizabethkingia anophelis AR6-8 ATC43370.1    
 CMV41_07420   Elizabethkingia anophelis AR6-8 ATC43369.1    
 A2T72_09195   Elizabethkingia anophelis CSID_3000521207 AMX51616.1    
 A2T72_09190   Elizabethkingia anophelis CSID_3000521207 AMX51615.1    
 A2T74_09195   Elizabethkingia anophelis CSID_3015183678 AMR41516.1    
 A2T74_09190   Elizabethkingia anophelis CSID_3015183678 AMR41515.1    
 A2T59_09190   Elizabethkingia anophelis CSID_3015183681 AMX55005.1    
 A2T59_09195   Elizabethkingia anophelis CSID_3015183681 AMX55006.1    
 A4C56_09195   Elizabethkingia anophelis CSID_3015183684 AMX48157.1    
 A4C56_09190   Elizabethkingia anophelis CSID_3015183684 AMX48156.1    
 AYC66_00150   Elizabethkingia anophelis E6809 AQX49190.1    
 AYC66_00145   Elizabethkingia anophelis E6809 AQX49189.1    
 AYC67_00150   Elizabethkingia anophelis F3543 AQX87530.1    
 AYC67_00145   Elizabethkingia anophelis F3543 AQX87529.1    
 A6J37_16600   Elizabethkingia anophelis FDAARGOS_198 ASV80102.1    
 A6J37_16595   Elizabethkingia anophelis FDAARGOS_198 ASV80101.1    
 M876_12970   Elizabethkingia anophelis FMS-007 AKH95479.1    
 M876_12965   Elizabethkingia anophelis FMS-007 AKH95478.1    
 BD94_3101   Elizabethkingia anophelis NUHP1 AIL46876.1    
 BD94_3102 (fragment)   Elizabethkingia anophelis NUHP1 AIL46877.1    
 BAZ09_007205   Elizabethkingia anophelis R26 ATC36013.1    
 BAZ09_007210   Elizabethkingia anophelis R26 ATC36014.1    
 BBD32_03510   Elizabethkingia endophytica F3201 AQX00595.1    
 BBD32_03505   Elizabethkingia endophytica F3201 AQX00594.1    
 BBD30_10775   Elizabethkingia endophytica JM-87 AQW94638.1    
 BBD30_10770   Elizabethkingia endophytica JM-87 AQW94637.1    
 AYC65_01395   Elizabethkingia genomosp. 3 str. G0146 AQX83754.1    
 AYC65_01390   Elizabethkingia genomosp. 3 str. G0146 AQX83753.1    
 BBD34_05315   Elizabethkingia genomosp. 4 str. G4123 AQX08097.1    
 BBD34_05310   Elizabethkingia genomosp. 4 str. G4123 AQX08096.1    
 BBD33_07425   Elizabethkingia meningoseptica G4076 AQX05088.1    
 BBD33_07420   Elizabethkingia meningoseptica G4076 AQX05087.1    
 BBD35_09600   Elizabethkingia meningoseptica G4120 AQX12610.1    
 BBD35_09595   Elizabethkingia meningoseptica G4120 AQX12609.1    
 B5G46_07415   Elizabethkingia meningoseptica KC1913 AQX47131.1    
 B5G46_07410   Elizabethkingia meningoseptica KC1913 AQX47130.1    
 VO54_03457 (Csla_2)   Elizabethkingia miricola BM10 AJW64887.1    
 VO54_03456 (Csla_1)   Elizabethkingia miricola BM10 AJW64886.1    
 CQS02_10620   Elizabethkingia miricola EM798-26 ATL43721.1    
 CQS02_10615   Elizabethkingia miricola EM798-26 ATL43720.1    
 EF62_0109   Enterococcus faecalis 62 ADX78406.1    
 A9R08_08085   Enterococcus faecalis AMB05 APS16473.1    
 DR75_1758   Enterococcus faecalis ATCC 29212 AIL05291.1    
 BZG32_03970   Enterococcus faecalis CLB21560 AQL52899.1    
 EFD32_0629   Enterococcus faecalis D32 AFO43519.1    
 EFD32_2606   Enterococcus faecalis D32 AFO45488.1    
 DENG_02916   Enterococcus faecalis DENG1 AHI41750.1    
 Sequence 326 from patent US 6448043 (fragment)   Enterococcus faecalis EF040 AAN89116.1
AAN89118.1
AAN89120.1
   
 CEQ16_05845   Enterococcus faecalis FDAARGOS_338 ASE65393.1    
 BSG25_11750   Enterococcus faecalis L12 APE73491.1    
 BMT03_02875   Enterococcus faecalis L9 APC55217.1    
 A3777_07965   Enterococcus faecalis LD33 AMR95590.1    
 A3777_07965   Enterococcus faecalis LD33 AMR95590.1    
 OG1RF_10550   Enterococcus faecalis OG1RF AEA93237.1    
 OG1RF_12303   Enterococcus faecalis OG1RF AEA94990.1    
 A6B47_03575   Enterococcus faecalis sorialis ARV02979.1    
 EFS1_2467   Enterococcus faecalis str. Symbioflor 1 CCO73545.1    
 EF0818   Enterococcus faecalis V583 AAO80631.1
AAR59670.1
NP_814561.1
Q837L8  
 EF3023   Enterococcus faecalis V583 AAO82707.1
AAR57166.1
AAR57723.1
NP_816637.1
Q82ZM8  
 Sequence 326 from patent US 6913907 (fragment)   Enterococcus faecalis V586 ABA13212.1
ABA13214.1
ABA13216.1
   
 EFW11_0563   Enterococcus faecalis W11 BAV35802.1    
 EFW11_2266   Enterococcus faecalis W11 BAV37505.1    
 M395_11255   Enterococcus faecium T110 AII40651.1    
 AL523_06180   Enterococcus gallinarum FDAARGOS_163 AMG49377.1    
 EHR_14305   Enterococcus hirae ATCC 9790 AFM71704.1    
 A6P53_03860   Enterococcus hirae R17 AND72041.1    
 EMQU_2462   Enterococcus mundtii QU 25 QU25 BAO08019.1    
 ATZ35_06015   Enterococcus rotai LMG 26678 ALS36724.1    
 ATZ33_14390   Enterococcus silesiacus LMG 23085 ALS03343.1    
 ENT_22740   Enterococcus sp. 7L76 CBL32606.1 D4ME62  
 CK496_10330   Enterococcus thailandicus a523 ASZ08284.1    
 A2I91_08800   Erysipelothrix rhusiopathiae GXBY-1 AMS11823.1    
 A2I91_03245   Erysipelothrix rhusiopathiae GXBY-1 AMS10808.1    
 A2I91_05680   Erysipelothrix rhusiopathiae GXBY-1 AMS11242.1    
 ERH_0150   Erysipelothrix rhusiopathiae str. Fujisawa BAK31209.1    
 ERH_0765 (HylB)   Erysipelothrix rhusiopathiae str. Fujisawa BAK31820.1    
 ERH_1210   Erysipelothrix rhusiopathiae str. Fujisawa BAK32264.1    
 K210_07905   Erysipelothrix rhusiopathiae SY1027 AGN25153.1    
 K210_01660   Erysipelothrix rhusiopathiae SY1027 AGN23967.1    
 K210_04195   Erysipelothrix rhusiopathiae SY1027 AGN24444.1    
 BC346_08320   Erysipelothrix rhusiopathiae WH13013 AOO68324.1    
 BC346_00860   Erysipelothrix rhusiopathiae WH13013 AOO66920.1    
 BC346_05200   Erysipelothrix rhusiopathiae WH13013 AOO67740.1    
 APECO2_17590   Escherichia coli APEC O2 AKK41761.1    
 BJJ90_04195   Escherichia coli SLK172 APT01279.1    
 A6C57_21910   Fibrella sp. ES10-3-2-2 ARK12776.1    
 FCOL_08260   Flavobacterium columnare ATCC 49512 AEW86467.1     3
 chondroitin AC lyase (CslA)   Flavobacterium columnare B067 ALD59777.1     3
 UN65_08590   Flavobacterium columnare B185 AMO20389.1     3
 AX766_05140   Flavobacterium columnare C#2 AND63848.1     3
 chondroitin AC lyase, partial (fragment)   Flavobacterium columnare CUVTE1232 AJW32178.1    
 chondroitin AC lyase (CslA;ChonAC) 4.2.2.5 Flavobacterium columnare G4 AAX07421.1 Q5EC33   3
 chondroitin AC lyase, partial (CslA)   Flavobacterium columnare MAC102 / G4 AFG23465.1     3
 Pf1_01408   Flavobacterium columnare Pf1 ANO49649.1     3
 AWN65_00325   Flavobacterium columnare strain 94-081 AMA48010.1     3
 BU993_07135   Flavobacterium columnare TC 1691 APT22415.1     3
 BIW12_15965   Flavobacterium commune PK15 APA00800.1     2
 BIW12_00075   Flavobacterium commune PK15 AOZ97964.1     2
 BIW12_15970   Flavobacterium commune PK15 APA00801.1    
 EM308_10950   Flavobacterium gilvum EM1308 AOW09985.1    
 BN863_29970   Formosa agariphila KMM 3901 CDF80709.1    
 AX769_05830   Frondihabitans sp. PAMC 28766 AMM19756.1    
 AciX8_2234   Granulicella mallensis MP5ACTX8 AEU36552.1    
 HBZC1_15820   Helicobacter bizzozeronii CIII-1 CCB80568.1    
 Hfelis_14140   Helicobacter felis ATCC 49179 CBY83498.1    
 ORF   Helicobacter heilmannii ASB1.4 CCM12033.1    
 SAMN04488563_1545   Jiangella alkaliphila DSM 45079 SDU40868.1    
 SAMN04515669_5496   Jiangella sp. DSM 45060 SDT65418.1    
 SAMN04515669_1144   Jiangella sp. DSM 45060 SDS45674.1    
 ORF   Kibdelosporangium sp. MJ126-NF4 CTQ98772.1    
 B7C62_00095   Kitasatospora albolonga YIM 101047 ARF70821.1    
 Kfla_2021   Kribbella flavida DSM 17836 ADB31112.1 D2PQX9  
 Kfla_6824   Kribbella flavida DSM 17836 ADB35815.1 D2Q2B9  
 KALB_2559   Kutzneria albida DSM 43870 AHH95927.1    
 KALB_5298 (fragment)   Kutzneria albida DSM 43870 AHH98660.1    
 LCA12A_0375   Lactobacillus casei 12A EKP96241.1    
 LCBD_2903   Lactobacillus casei BD-II AEA58397.1    
 LCABL_28750 (XalA)   Lactobacillus casei BL23 CAQ67925.1 B3WB56  
 LC2W_2877   Lactobacillus casei LC2W AEA55206.1    
 BGL52_13280   Lactobacillus casei LC5 ARY92677.1    
 LOCK919_2937   Lactobacillus casei LOCK919 AGP69600.1    
 LCAZH_2685   Lactobacillus casei str. Zhang ADK19871.1 D8GDJ4  
 BN194_28200   Lactobacillus casei W56 CCK23767.1    
 ABB44_09390   Lactobacillus farciminis CNCM-I-3699-R AKS52111.1    
 ABB45_09370   Lactobacillus farciminis CNCM-I-3699-S AKP03806.1    
 LSEI_2687   Lactobacillus paracasei ATCC 334 ABJ71405.1 Q034G7  
 A3778_10500   Lactobacillus paracasei IIA ARE44489.1    
 LPL9_2772 (fragment)   Lactobacillus paracasei L9 AKU60826.1    
 LBPG_01276   Lactobacillus paracasei subsp. paracasei 8700:2 EEQ65827.1    
 LBPC_2660   Lactobacillus paracasei subsp. paracasei JCM 8130 BAN72956.1    
 A0F16_11435   Lactobacillus rhamnosus ASCC 290 AMQ04026.1    
 LRHK_2805   Lactobacillus rhamnosus ATCC 8530 AER65523.1    
 LC705_02696   Lactobacillus rhamnosus Lc 705 CAR91535.1 C7TMV1  
 LOCK900_2695   Lactobacillus rhamnosus LOCK900 AGP72472.1    
 LOCK908_2776   Lactobacillus rhamnosus LOCK908 AGP75382.1    
 BGK71_12765   Lactobacillus rhamnosus LR5 ASX18232.1    
 BVH57_01895   Lactobacillus rhamnosus Pen ARD31258.1    
 BFR49_10895 (fragment)   Lactococcus lactis subsp. lactis WFLU12 ASX25169.1    
 BFR49_10900 (fragment)   Lactococcus lactis subsp. lactis WFLU12 ASX25170.1    
 SAMN04515683_3564   Leifsonia sp. 157MF SDK47213.1    
 SAMN04515690_0582   Leifsonia sp. 197AMF SDH07438.1    
 SAMN04515680_3029   Leifsonia sp. 21MFCrub1.1 SEB07332.1    
 SAMN04515684_3201   Leifsonia sp. 466MF SDJ32702.1    
 SAMN04515685_3546   Leifsonia sp. 467MF SEN56312.1    
 SAMN04515686_1386   Leifsonia sp. 509MF SDN53793.1    
 SAMN04515691_3435   Leifsonia sp. 98AMF SFM73036.1    
 UE46_15580   Listeria weihenstephanensis WS 4560 AQY52297.1    
 UE46_14495   Listeria weihenstephanensis WS 4560 AQY52590.1    
 VV02_06880   Luteipulveratus mongoliensis MN07-A0370 AKU15639.1    
 ALGA_3393   Marinifilaceae bacterium SPP2 BAX81691.1    
 AB663_001102   Microbacterium sp. XT11 ALX66168.1    
 MTES_2849   Microbacterium testaceum StLB037 BAJ75813.1    
 SAMN04489812_4258   Microlunatus soli DSM 21800 SDT13119.1    
 MCRO_0392   Mycoplasma crocodyli MP145 ADE19838.1 D5E5I1  
 MFE_04780   Mycoplasma fermentans JER ADN69073.1 E1PST4  
 MfeM64YM_0614   Mycoplasma fermentans M64 ADV34612.1    
 MBIO_0039   Mycoplasma fermentans PG18 BAH69304.1 C4XDT2  
 BLA55_00250   Mycoplasma pullorum B359_6 APJ38126.1    
 A8C56_12645   Niabella ginsenosidivorans BS26 ANH81716.1    
 A8C56_05425   Niabella ginsenosidivorans BS26 ANH80504.1     2
 NIASO_15730   Niabella soli DSM 19437 AHF16211.1     2
 NIASO_08255   Niabella soli DSM 19437 AHF15153.1    
 Niako_2983   Niastella koreensis GR20-10 AEV99313.1     3
 BN4615_P3407   Nonomuraea gerenzanensis ATCC 39727 SBO93891.1    
 BN4615_P10725   Nonomuraea gerenzanensis ATCC 39727 SBP01209.1    
 BN4615_P9424   Nonomuraea gerenzanensis ATCC 39727 SBO99908.1    
 BN4615_P494   Nonomuraea gerenzanensis ATCC 39727 SBO90980.1    
 BN4615_P10280   Nonomuraea gerenzanensis ATCC 39727 SBP00764.1    
 BKM31_31155   Nonomuraea sp. ATCC 55076 AQZ65316.1    
 BKM31_49760   Nonomuraea sp. ATCC 55076 AQZ68491.1    
 BKM31_46745   Nonomuraea sp. ATCC 55076 AQZ67968.1    
 BKM31_51920   Nonomuraea sp. ATCC 55076 AQZ68861.1    
 BKM31_55970   Nonomuraea sp. ATCC 55076 AQZ71379.1    
 Oter_4325   Opitutus terrae PB90-1 ACB77597.1 B1ZPA8  
 Ornrh_0807   Ornithobacterium rhinotracheale DSM 15997 AFL97003.1     2
 Ornrh_0305   Ornithobacterium rhinotracheale DSM 15997 AFL96523.1     2
 Ornrh_0808   Ornithobacterium rhinotracheale DSM 15997 AFL97004.1     3
 Q785_04595   Ornithobacterium rhinotracheale ORT-UMN 88 AIP99140.1     2
 Q785_01660   Ornithobacterium rhinotracheale ORT-UMN 88 AIQ00290.1     2
 Q785_04600   Ornithobacterium rhinotracheale ORT-UMN 88 AIP99141.1     3
 chondroitin AC lyase (partial) 4.2.2.1
4.2.2.5
Paenarthrobacter aurescens   P84141 1RWA[A]
1RWC[A]
1RWF[A]
1RWG[A]
1RWH[A]
1RW9[A]
 AAur_3068   Paenarthrobacter aurescens TC1 ABM09726.1 A1R957  
 xanthan lyase (XalA) 4.2.2.12 Paenibacillus alginolyticus XL-1 AAG24953.1 Q9F8Q9  
 XalB   Paenibacillus alginolyticus XL-1 AAG42262.1 Q9EYM9  
 PBOR_18695   Paenibacillus borealis DSM 13188 AIQ58740.1    
 A3958_01915   Paenibacillus glucanolyticus 5162 ANA78826.1    
 BBD41_14780   Paenibacillus ihbetae IHBB 9852 ANY73736.1    
 BXP28_07675   Paenibacillus larvae subsp. larvae ATCC 9545 AQR79691.1    
 ERIC2_c23740   Paenibacillus larvae subsp. larvae DSM 25430 AHD06163.1    
 B5S25_00095   Paenibacillus larvae subsp. pulvifaciens CCM 38 AQZ45223.1    
 B7C51_20880   Paenibacillus larvae subsp. pulvifaciens SAG 10367 ARF69767.1    
 PM3016_2533   Paenibacillus mucilaginosus 3016 AFC29417.1    
 PM3016_4924   Paenibacillus mucilaginosus 3016 AFC31656.1    
 PM3016_4630   Paenibacillus mucilaginosus 3016 AFC31376.1    
 B2K_12830   Paenibacillus mucilaginosus K02 AFH61594.1
AFK65368.1
   
 B2K_25515   Paenibacillus mucilaginosus K02 AFH64003.1    
 B2K_24000   Paenibacillus mucilaginosus K02 AFH63711.2    
 KNP414_05237   Paenibacillus mucilaginosus KNP414 AEI43761.1    
 KNP414_05560   Paenibacillus mucilaginosus KNP414 AEI44084.1    
 KNP414_02262   Paenibacillus mucilaginosus KNP414 AEI40823.1    
 PRIO_0266   Paenibacillus riograndensis SBR5 CQR51520.1    
 P40081_18995   Paenibacillus sp. FSL P4-0081 AIQ30011.1    
 R50912_17565   Paenibacillus sp. FSL R5-0912 AIQ41646.1    
 Pjdr2_3195   Paenibacillus sp. JDR-2 ACT01837.1 C6D1H3  
 SY83_13390   Paenibacillus swuensis DY6 ANE47090.1    
 SAMN05661091_5261   Paenibacillus uliginis N3/975 SMF90851.1    
 chondroitin AC lyase (CslA;ChnAC;Phep_0786) 4.2.2.5 Pedobacter heparinus DSM 2366 ACU03008.1
AAC83383.1
Q59288 1CB8[A]
1HM2[A]
1HM3[A]
1HMU[A]
1HMW[A]
3
 Phep_3979   Pedobacter heparinus DSM 2366 ACU06170.1 C6XVU5  
 Phep_0784   Pedobacter heparinus DSM 2366 ACU03006.1 C6Y213   2
 Phep_2838   Pedobacter heparinus DSM 2366 ACU05037.1 C6Y1P5   2
 Phep_3863   Pedobacter heparinus DSM 2366 ACU06054.1 C6XV46  
 Phep_3972   Pedobacter heparinus DSM 2366 ACU06163.1 C6XVT8  
 AQ505_08345   Pedobacter sp. PACM 27299 ALL08699.1     2
 AQ505_08355   Pedobacter sp. PACM 27299 ALL05500.1     3
 CAY62_18680   Photobacterium damselae subsp. damselae KC-Na-1 ARR51439.1     2
 PDPUS_2_01248   Photobacterium damselae subsp. piscicida 91-197 BAX55832.1     2
 PDPUS_2_01252   Photobacterium damselae subsp. piscicida 91-197 BAX55837.1    
 H744_2c1762   Photobacterium gaetbulicola Gung47 AJR08428.1     2
 H744_2c1761   Photobacterium gaetbulicola Gung47 AJR08427.1     2
 H744_2c1789   Photobacterium gaetbulicola Gung47 AJR08455.1     2
 H744_2c1785   Photobacterium gaetbulicola Gung47 AJR08451.1     2
 PBPRB0153   Photobacterium profundum SS9 CAG22026.1     2
 SMSP2_01425 (Chonabc_2)   Phycisphaerae bacterium SM-Chi-D1 AQQ71061.1     2
 SMSP2_01417 (Chonabc_1)   Phycisphaerae bacterium SM-Chi-D1 AQQ71053.1     2
 STSP2_00558 (CslA)   Phycisphaerae bacterium ST-NAGAB-D1 AQT67414.1    
 Prede_1246   Prevotella dentalis DSM 3688 AGB28568.1     2
 PAZ_c03930 (HylB)   Propionibacterium acnes 266 AEE71593.1    
 TIB1ST10_01945   Propionibacterium acnes 6609 AEH28699.1    
 PAC1_01925   Propionibacterium acnes C1 AFU40163.1    
 TIA1EST1_01875   Propionibacterium acnes hdn-1 AID35311.1    
 PAGK_0394   Propionibacterium acnes HL096PA1 AGJ79255.1    
 PPA0380 (hyaluronate lyase) 4.2.2.1 Propionibacterium acnes KPA171202 AAT82132.1 P0CZ01  
 HMPREF0675_3415   Propionibacterium acnes SK137 ADD99051.1 D4HB55  
 TIIST44_06625   Propionibacterium acnes subsp. defendens ATCC 11828 AER05804.1    
 TIA2EST22_01875   Propionibacterium acnes TypeIA2 P.acn17 AEW80707.1    
 TIA2EST36_01855   Propionibacterium acnes TypeIA2 P.acn31 AEW82972.1    
 TIA2EST2_01795   Propionibacterium acnes TypeIA2 P.acn33 AEW78466.1    
 BCB70_04600   Propionibacterium sp. oral taxon 193 F0672 AOH46650.1    
 PSM36_3149   Proteiniphilum saccharofermentans SCD21938.1    
 PSM36_3149   Proteiniphilum saccharofermentans SCD21938.1    
 Sequence 7112 from patent US 6605709   Proteus mirabilis AAR43842.1     2
 Sequence 7181 from patent US 6605709   Proteus mirabilis AAR43911.1     2
 AOUC001_04155   Proteus mirabilis AOUC-001 AND12101.1     2
 AOUC001_04160   Proteus mirabilis AOUC-001 AND12102.1     2
 AM438_10570   Proteus mirabilis AR_0059 ARA22905.1     2
 AM438_10565   Proteus mirabilis AR_0059 ARA22904.1     2
 AM402_07160   Proteus mirabilis AR_0155 ARX33937.1     2
 AM402_07165   Proteus mirabilis AR_0155 ARX33938.1     2
 AM403_16060   Proteus mirabilis AR_0156 ASB03099.1     2
 AM403_16065   Proteus mirabilis AR_0156 ASB03100.1     2
 AM405_16155   Proteus mirabilis AR_0159 ARX10318.1     2
 AM405_16160   Proteus mirabilis AR_0159 ARX10319.1     2
 BB2000_2202   Proteus mirabilis BB2000 AGS60667.1     2
 BB2000_2203   Proteus mirabilis BB2000 AGS60668.1     2
 AOC00_12415   Proteus mirabilis CYPM1 ALE22970.1     2
 AOC00_12420   Proteus mirabilis CYPM1 ALE22971.1     2
 PMI2127   Proteus mirabilis HI4320 CAR44246.1 B4F1D7   2
 PMI2128   Proteus mirabilis HI4320 CAR44248.1 B4F1D8   2
 BG029_15270   Proteus mirabilis T18 ATC79727.1     2
 BG029_15275   Proteus mirabilis T18 ATC79728.1     2
 BG257_10960   Proteus mirabilis T21 ATC75109.1     2
 BG257_10965   Proteus mirabilis T21 ATC75110.1     2
 chondroitin ABC lyase I / chondroitinase ABC (ChABC) 4.2.2.20 Proteus vulgaris 2109195A
ABE23097.1
ACN04689.1
ACQ12496.1
ACQ12497.1
ACW17440.1
ACW17441.1
ACY01450.1
P59807 1HN0[A] 2
 chondroitin ABC lyase II (ChABCII) 4.2.2.20 Proteus vulgaris ATCC 6896 AAB43333.1
ABU46331.1
  cryst 2
 choindroitinase ABC   Proteus vulgaris ATCC 9920D ADK74774.1 E2J154   2
 AOB99_12450   Proteus vulgaris CYPV1 ALE26129.1     2
 AOB99_12455   Proteus vulgaris CYPV1 ALE26130.1     2
 CRN77_08485   Proteus vulgaris FDAARGOS_366 ATM99761.1     2
 CRN77_08480   Proteus vulgaris FDAARGOS_366 ATM99760.1     2
 chondroitinase ABC I   Proteus vulgaris KCTC 2579 ALL74069.1     2
 S4054_13690   Pseudoalteromonas luteoviolacea S4054 AOT18674.1     2
 S40542_13685   Pseudoalteromonas luteoviolacea S40542 AOT13760.1     2
 S4054249_13715   Pseudoalteromonas luteoviolacea S4054249 AOT08847.1     2
 NJ69_21650   Pseudomonas parafulva CRS01-1 AIZ35416.1    
 PSPPH_1510   Pseudomonas savastanoi pv. phaseolicola 1448A AAZ36518.1 Q48LG0  
 AFB00_01910   Pseudonocardia sp. HH130630-07 ANY05272.1    
 Pedsa_0057   Pseudopedobacter saltans DSM 12145 ADY50645.1    
 Pedsa_3805   Pseudopedobacter saltans DSM 12145 ADY54334.1     2
 Pedsa_3808   Pseudopedobacter saltans DSM 12145 ADY54337.1     3
 TH63_11990   Rufibacter sp. DG31D AKQ46181.1    
 Runsl_2790   Runella slithyformis DSM 19594 AEI49183.1    
 SARI_02380   Salmonella enterica subsp. arizonae serovar 62:z4,z23:- str. RSK2980 ABX22243.1 A9ML73   2
 UQ48_03940   Salmonella enterica subsp. diarizonae 11-01853 ANA23904.1    
 UQ48_06900   Salmonella enterica subsp. diarizonae 11-01853 ANA24438.1     2
 UQ49_06910   Salmonella enterica subsp. diarizonae 11-01854 ANA28782.1     2
 UQ49_03945   Salmonella enterica subsp. diarizonae 11-01854 ANA28245.1    
 UQ50_06900   Salmonella enterica subsp. diarizonae 11-01855 ANA20216.1     2
 UQ50_03940   Salmonella enterica subsp. diarizonae 11-01855 ANA19682.1    
 CNQ75_14895   Salmonella enterica subsp. diarizonae HZS154 ATW55688.1     2
 CNQ75_00080   Salmonella enterica subsp. diarizonae HZS154 ATW53075.1    
 LFZ53_18585   Salmonella enterica subsp. diarizonae serovar 50:k:z str. MZ0080 ASG76989.1     2
 LFZ53_21715   Salmonella enterica subsp. diarizonae serovar 50:k:z str. MZ0080 ASG77540.1    
 LFZ55_20775   Salmonella enterica subsp. diarizonae serovar 65:c:z str. SA20044251 ASG85154.1    
 LFZ55_17770   Salmonella enterica subsp. diarizonae serovar 65:c:z str. SA20044251 ASG84619.1     2
 LFZ47_20660   Salmonella enterica subsp. salamae serovar 55:k:z39 str. 1315K ASG89772.1    
 CA265_00740   Sphingobacteriaceae bacterium GW460-11-11-14-LB5 ARS38291.1     3
 CA265_05500   Sphingobacteriaceae bacterium GW460-11-11-14-LB5 ARS39156.1    
 CA265_06790   Sphingobacteriaceae bacterium GW460-11-11-14-LB5 ARS39373.1     3
 BV902_04995   Sphingobacterium sp. B29 APU95771.1     3
 Snas_0850   Stackebrandtia nassauensis DSM 44728 ADD40561.1 D3Q856  
 EP23_10455   Staphylococcus agnetis 908 ALN77731.1     1
 A7971_10850   Staphylococcus argenteus BN75 API80121.1     1
 SAMSHR1132_20330   Staphylococcus argenteus MSHR1132 CCE59861.1     1
 SA2981_2139 (HysA)   Staphylococcus aureus 04-02981 ADC38350.1 D3EYM7   1
 A7P66_13795   Staphylococcus aureus 08-02119 ANI72784.1     1
 A7P66_01580   Staphylococcus aureus 08-02119 ANI70472.1     1
 A7327_09565   Staphylococcus aureus 08-02300 ANI74717.1     1
 A7327_11800   Staphylococcus aureus 08-02300 ANI75096.1     1
 C248_1856 (Hysa1)   Staphylococcus aureus 08BA02176 AFR73846.1     1
 C248_2244 (Hysa2)   Staphylococcus aureus 08BA02176 AFR74184.1     1
 UC18_10825   Staphylococcus aureus 144_S7 AJP27938.1     1
 CH51_11910   Staphylococcus aureus 2395 USA500 AIL58705.1     1
 RM27_11900   Staphylococcus aureus 25b_MRSA AJC40962.1     1
 RM31_11905   Staphylococcus aureus 26b_MRSA AJC38123.1     1
 RM28_11895   Staphylococcus aureus 27b_MRSA AJC43808.1     1
 BXP64_11280   Staphylococcus aureus 293G ARH67491.1     1
 BXP64_08875   Staphylococcus aureus 293G ARH67096.1     1
 RM29_11900   Staphylococcus aureus 29b_MRSA AJC29585.1     1
 RM30_11895   Staphylococcus aureus 31b_MRSA AJC32431.1     1
 QT38_11895   Staphylococcus aureus 33b AJC35274.1     1
 CH52_07940   Staphylococcus aureus 502A AHM70243.1     1
 TW63_10875   Staphylococcus aureus 71A_S11 AJP20628.1     1
 UC19_10810   Staphylococcus aureus 79_S10 AJP30572.1     1
 hyaluronate lyase (HysA) 4.2.2.1 Staphylococcus aureus 8325-4 AAA82984.1 Q59801   1
 UG86_11545   Staphylococcus aureus 93b_S9 AJP66629.1     1
 SABB155_16940   Staphylococcus aureus BB155 CRL36886.1     1
 SABB_04270 (HysA)   Staphylococcus aureus Bmb9393 AGP29148.1     1
 BJN19_12295   Staphylococcus aureus C2406 ARH58861.1     1
 CA347_2289   Staphylococcus aureus CA-347 AGO30580.1     1
 EQ80_011135   Staphylococcus aureus CA12 ALK40027.1     1
 EQ90_11135   Staphylococcus aureus CA15 AKK61897.1     1
 AB525_10710   Staphylococcus aureus CFSAN007835 ATN61187.1     1
 AB520_11760   Staphylococcus aureus CFSAN007847 ATN58649.1     1
 AB520_09070   Staphylococcus aureus CFSAN007847 ATN58184.1     1
 AB526_11350   Staphylococcus aureus CFSAN007850 ATN55868.1     1
 AB454_11150   Staphylococcus aureus CFSAN007851 ATN53159.1     1
 AB478_11010   Staphylococcus aureus CFSAN007883 ATN50511.1     1
 AB466_10995   Staphylococcus aureus CFSAN007894 ATN47802.1     1
 FCFHV36_2129 (HysA)   Staphylococcus aureus FCFHV36 AKB00276.1     1
 SAFDA_2073 (HysA)   Staphylococcus aureus FDA209P BAS52274.1     1
 SAFDA_1691 (HysA)   Staphylococcus aureus FDA209P BAS51892.1     1
 AL519_07765   Staphylococcus aureus FDAARGOS_159 AMG41931.1     1
 CO684_10420   Staphylococcus aureus FDAARGOS_412 ATF39711.1     1
 FORC12_1357   Staphylococcus aureus FORC_012 AMO17735.1     1
 FORC26_1939   Staphylococcus aureus FORC_026 APC77954.1     1
 FORC27_2266   Staphylococcus aureus FORC_027 AOO99504.1     1
 FORC39_2074   Staphylococcus aureus FORC_039 ARR26885.1     1
 FORC40_2024   Staphylococcus aureus FORC_040 ASI56228.1     1
 FORC45_2142   Staphylococcus aureus FORC_045 ASF33103.1     1
 BZK08_12060   Staphylococcus aureus GD1539 ARH75692.1     1
 BZK08_09745   Staphylococcus aureus GD1539 ARH75309.1     1
 BZK09_09590   Staphylococcus aureus GD1677 ARH78058.1     1
 BZK09_11715   Staphylococcus aureus GD1677 ARH78388.1     1
 BZJ79_09260   Staphylococcus aureus GD5 ARH69813.1     1
 BZJ79_11565   Staphylococcus aureus GD5 ARH70191.1     1
 BZK07_09565   Staphylococcus aureus GD705 ARH72523.1     1
 BZK07_11940   Staphylococcus aureus GD705 ARH72914.1     1
 AM595_11490   Staphylococcus aureus HOU1444-VR ALC95145.1     1
 ER12_011120   Staphylococcus aureus HUV05 ALK37424.1     1
 B7437_11670   Staphylococcus aureus HZW450 ATH58180.1     1
 Hyaluronate lyase precursor   Staphylococcus aureus ILRI_Eymole1/1 CEH26625.1     1
 Hyaluronate lyase precursor   Staphylococcus aureus ILRI_Eymole1/1 CEH27027.1     1
 A2V17_11710   Staphylococcus aureus ISU935 ASC51731.1     1
 B7H15_12255   Staphylococcus aureus JE2 ARG46765.1     1
 JSA_2099 (Hysa1)   Staphylococcus aureus JH4899 BAX06658.1     1
 JP02758_1726   Staphylococcus aureus JP080 BBA24436.1     1
 JP02758_2044   Staphylococcus aureus JP080 BBA24754.1     1
 BN843_22440   Staphylococcus aureus M1 CCW22529.1     1
 EP54_11590   Staphylococcus aureus M121 AKK59333.1     1
 CKU_1961   Staphylococcus aureus MCRF184 AMQ78509.1     1
 SAMI_2178 (HysA)   Staphylococcus aureus MI BAU35763.1     1
 NI36_10880   Staphylococcus aureus MS4 ALR00310.1     1
 ASL16_12310   Staphylococcus aureus NCCP14558 AND31156.1     1
 ASL15_11955   Staphylococcus aureus NCCP14562 AND33979.1     1
 ERS445051_02162   Staphylococcus aureus NCTC13435 CKH38658.1     1
 ERS445052_01191 (HysA)   Staphylococcus aureus NCTC8532 CKH21026.1     1
 SANO10_2156   Staphylococcus aureus No.10 BAX76083.1     1
 X998_2189   Staphylococcus aureus NRS 100 AHW65937.1     1
 SaO11_02005 (HysA)   Staphylococcus aureus O11 ATV04831.1     1
 SAB1663   Staphylococcus aureus RF122 CAI81352.1 Q2YTM9   1
 SAB2082   Staphylococcus aureus RF122 CAI81771.1 Q2YYI7   1
 AUC48_11215   Staphylococcus aureus RIVM1295 ALS70509.1     1
 AUC48_09270   Staphylococcus aureus RIVM1295 ALS70183.1     1
 AUC49_09105   Staphylococcus aureus RIVM1607 ALS72795.1     1
 AUC49_11055   Staphylococcus aureus RIVM1607 ALS73120.1     1
 AUC50_11830   Staphylococcus aureus RIVM3897 ALS86517.1     1
 AUC50_09585   Staphylococcus aureus RIVM3897 ALS86132.1     1
 A5J11_00770   Staphylococcus aureus RIVM6519 AMX43588.1     1
 AA961_11150   Staphylococcus aureus RKI4 AKJ49961.1     1
 UC16_09330   Staphylococcus aureus SA17_S6 AJP22991.1     1
 RT87_11360   Staphylococcus aureus SA564 ALD81728.1     1
 BRL61_11780   Staphylococcus aureus SJTUF_J27 APW76572.1     1
 BRL61_09400   Staphylococcus aureus SJTUF_J27 APW76188.1     1
 BZP34_13665   Staphylococcus aureus SR434 AQD20257.1     1
 SAST38_03850   Staphylococcus aureus ST20130938 AMV88208.1     1
 SAST38_02898 (HysA)   Staphylococcus aureus ST20130938 AMV88533.1     1
 SAST39_04518   Staphylococcus aureus ST20130939 AMV90824.1     1
 SAST39_02879 (HysA)   Staphylococcus aureus ST20130939 AMV91149.1     1
 SAST40_03012 (HysA)   Staphylococcus aureus ST20130940 AMV78113.1     1
 SAST40_04426 (HysA)   Staphylococcus aureus ST20130940 AMV77782.1     1
 SAST41_03888   Staphylococcus aureus ST20130941 AMV80323.1     1
 SAST41_03034 (HysA)   Staphylococcus aureus ST20130941 AMV80654.1     1
 SAST42_02971 (HysA)   Staphylococcus aureus ST20130942 AMV83258.1     1
 SAST43_02947   Staphylococcus aureus ST20130943 AMV85902.1     1
 EDCC5055_02183   Staphylococcus aureus subsp. aureus SIN24782.1     1
 MS7_2224   Staphylococcus aureus subsp. aureus 11819-97 AEW66178.1     1
 A7Q05_0550 (fragment)   Staphylococcus aureus subsp. aureus 1625.CO1 AOH66587.1     1
 A7U52_0534 (fragment)   Staphylococcus aureus subsp. aureus 1969.N AOH64085.1     1
 A7U47_0554 (fragment)   Staphylococcus aureus subsp. aureus 1971.CO1 AOH61225.1     1
 A7U45_0555 (fragment)   Staphylococcus aureus subsp. aureus 2148.CO1 AOH88400.1    
 A7U45_0554 (fragment)   Staphylococcus aureus subsp. aureus 2148.CO1 AOH88503.1     1
 A7U44_0529   Staphylococcus aureus subsp. aureus 2148.N AOH58594.1     1
 A7U51_2422 (fragment)   Staphylococcus aureus subsp. aureus 5118.N AOH72494.1     1
 A7U51_2421 (fragment)   Staphylococcus aureus subsp. aureus 5118.N AOH72555.1    
 SAAG_00036   Staphylococcus aureus subsp. aureus 55/2053 EEV04812.1     1
 SAAG_01706   Staphylococcus aureus subsp. aureus 55/2053 EEV03757.2     1
 RSAU_001662 (HysA)   Staphylococcus aureus subsp. aureus 6850 AGU55481.1     1
 RSAU_002045 (Hysa2)   Staphylococcus aureus subsp. aureus 6850 AGU55802.1     1
 ST398NM01_1880   Staphylococcus aureus subsp. aureus 71193 AFH70038.1     1
 ST398NM01_2262   Staphylococcus aureus subsp. aureus 71193 AFH70453.1     1
 KQ76_11490   Staphylococcus aureus subsp. aureus ATCC 25923 AIO21839.1     1
 SABE62_02552 (HysA)   Staphylococcus aureus subsp. aureus Be62 ALY24110.1     1
 SAKOR_02172   Staphylococcus aureus subsp. aureus CN1 AGU62312.1     1
 SA2194   Staphylococcus aureus subsp. aureus COL AAW37070.1 Q5HE02   1
 AA076_11225   Staphylococcus aureus subsp. aureus DSM 20231 AKJ18033.1     1
 ECTR2_2063   Staphylococcus aureus subsp. aureus ECT-R 2 CBX35392.1 E5R9T7   1
 SAOV_2247   Staphylococcus aureus subsp. aureus ED133 ADI98688.1 D8HDV0   1
 SAAV_2263   Staphylococcus aureus subsp. aureus ED98 ACY12098.1 D0K7K4   1
 CFN12_12075   Staphylococcus aureus subsp. aureus EDCC5458 ATW78253.1     1
 CFN13_11305   Staphylococcus aureus subsp. aureus EDCC5464 ATW80921.1     1
 FORC1_2143   Staphylococcus aureus subsp. aureus FORC_001 AIW27891.1     1
 FORC1_1755   Staphylococcus aureus subsp. aureus FORC_001 AIW27503.1     1
 RT44_11445   Staphylococcus aureus subsp. aureus GR2 ALF33911.1     1
 SAGV51_03869   Staphylococcus aureus subsp. aureus Gv51 ALY27460.1     1
 SAGV69_02662 (HysA)   Staphylococcus aureus subsp. aureus Gv69 AIU86138.1     1
 SAGV88_02555 (HysA)   Staphylococcus aureus subsp. aureus Gv88 ALY29846.1     1
 ER16_11200   Staphylococcus aureus subsp. aureus H-EMRSA-15 AIA00028.1     1
 SAHC1335_00163 (HysA)   Staphylococcus aureus subsp. aureus HC1335 ALY19127.1     1
 SAHC1340_00022 (HysA)   Staphylococcus aureus subsp. aureus HC1340 ALY16155.1     1
 SAEMRSA15_21070 (Hysa2)   Staphylococcus aureus subsp. aureus HO 5096 0412 CCG16818.1     1
 A2U18_09335   Staphylococcus aureus subsp. aureus ISU926 ASC54065.1     1
 A2U18_11580   Staphylococcus aureus subsp. aureus ISU926 ASC54447.1     1
 SaurJH1_2271   Staphylococcus aureus subsp. aureus JH1 ABR53099.1 A6U3T1   1
 SaurJH9_2232   Staphylococcus aureus subsp. aureus JH9 ABQ50013.1 A5IUZ0   1
 SAA6159_01731   Staphylococcus aureus subsp. aureus JKD6159 ADL23664.1 D9RI92   1
 SAA6159_02114   Staphylococcus aureus subsp. aureus JKD6159 ADL24036.1 D9RC72   1
 ACH32_04395   Staphylococcus aureus subsp. aureus JS395 ALH97566.1     1
 ACH32_01905   Staphylococcus aureus subsp. aureus JS395 ALH97145.1     1
 AS852_11575   Staphylococcus aureus subsp. aureus LA-MRSA ST398 APE89246.1     1
 AS852_09330   Staphylococcus aureus subsp. aureus LA-MRSA ST398 APE88864.1     1
 SARLGA251_16860 (HysA)   Staphylococcus aureus subsp. aureus LGA251 CCC88453.1     1
 SARLGA251_19960 (HysA)   Staphylococcus aureus subsp. aureus LGA251 CCC88761.1     1
 M013TW_2169   Staphylococcus aureus subsp. aureus M013 AEV79162.1     1
 M013TW_1815 (fragment)   Staphylococcus aureus subsp. aureus M013 AEV78865.1     1
 SAR2292 (HysA2)   Staphylococcus aureus subsp. aureus MRSA252 CAG41271.1 Q6GEM7   1
 SAR1892 (HysA1)   Staphylococcus aureus subsp. aureus MRSA252 CAG40881.1 Q6GFP8   1
 SAS2103   Staphylococcus aureus subsp. aureus MSSA476 CAG43912.1 Q6G7B1   1
 SAHV_2186   Staphylococcus aureus subsp. aureus Mu3 BAF79069.1 A7X590   1
 SAV2202 (HysA)   Staphylococcus aureus subsp. aureus Mu50 BAB58364.1
BAB45130.1
NP_372726.1
Q99S67   1
 MW2129 (HysA)   Staphylococcus aureus subsp. aureus MW2 BAB95994.1
NP_646946.1
Q8NVC3   1
 SA2003 (HysA)   Staphylococcus aureus subsp. aureus N315 BAB43294.1
NP_375315.1
Q7A486   1
 SAOUHSC_02463   Staphylococcus aureus subsp. aureus NCTC 8325 ABD31483.1 Q59801   1
 CNH36_12380   Staphylococcus aureus subsp. aureus Newman ATC72380.1     1
 SA268_1749 (fragment)   Staphylococcus aureus subsp. aureus SA268 AII56316.1     1
 SA268_2111 (HysA)   Staphylococcus aureus subsp. aureus SA268 AII56678.1     1
 SA40_1956 (HysA)   Staphylococcus aureus subsp. aureus SA40 AGW36999.1     1
 SA957_2040 (HysA)   Staphylococcus aureus subsp. aureus SA957 AGW34535.1     1
 SAI1T1_2016390 (HysA)   Staphylococcus aureus subsp. aureus ST228 CCJ11549.1
CCJ13514.1
CCJ15478.1
CCJ19406.1
CCJ21370.1
CCJ23338.1
CCJ25304.1
CCJ27269.1
    1
 SAPIG1880   Staphylococcus aureus subsp. aureus ST398 CAQ50304.1 D2N8F6   1
 SAPIG2262   Staphylococcus aureus subsp. aureus ST398 CAQ50642.1 D2N9E4   1
 RU53_2270 (HysA)   Staphylococcus aureus subsp. aureus ST772-MRSA-V DAR4145 AJE65591.1     1
 SAA6008_02243 (HysA)   Staphylococcus aureus subsp. aureus str. JKD6008 ADL66257.1 D9RPN3   1
 CNH35_12380   Staphylococcus aureus subsp. aureus str. Newman ATC68535.1     1
 NWMN_2106   Staphylococcus aureus subsp. aureus str. Newman BAF68378.1 A6QJ46   1
 SAT0131_02378   Staphylococcus aureus subsp. aureus T0131 AEB89302.1     1
 Tgr_1999 (fragment)   Staphylococcus aureus subsp. aureus Tager 104 AMO53576.1     1
 Tgr_2436   Staphylococcus aureus subsp. aureus Tager 104 AMO53963.1     1
 HMPREF0772_10989 (HysA)   Staphylococcus aureus subsp. aureus TCH60 ADQ76451.1 E5QQN6   1
 HMPREF0772_11345 (Hysa2)   Staphylococcus aureus subsp. aureus TCH60 ADQ76807.1 E5QTA9   1
 SAJPND1_02181   Staphylococcus aureus subsp. aureus TMUS2126 BAR09692.1     1
 SAJPND4_02181   Staphylococcus aureus subsp. aureus TMUS2134 BAR12416.1     1
 SATW20_23400 (HysA)   Staphylococcus aureus subsp. aureus TW20 CBI50206.1 D1GRH5   1
 BSG37_11925   Staphylococcus aureus subsp. aureus UCI 28 APZ41022.1     1
 AC807_2333   Staphylococcus aureus subsp. aureus USA300_2014.C01 AKR52372.1     1
 ACO02_1429   Staphylococcus aureus subsp. aureus USA300_2014.C02 AKR46169.1     1
 SAUSA300_2161   Staphylococcus aureus subsp. aureus USA300_FPR3757 ABD22109.1     1
 LG33_12410   Staphylococcus aureus subsp. aureus USA300_SUR1 APW51799.1     1
 USA300HOU_2197   Staphylococcus aureus subsp. aureus USA300_TCH1516 ABX30190.1 A8Z313   1
 SAVC_09900   Staphylococcus aureus subsp. aureus VC40 AEZ38132.1     1
 SAZ172_2305 (HysA)   Staphylococcus aureus subsp. aureus Z172 AGY90405.1     1
 EX97_11340   Staphylococcus aureus UA-S391_USA300 AIA28693.1     1
 BSG38_12410   Staphylococcus aureus UCI62 APZ38202.1     1
 AZ30_11650   Staphylococcus aureus USA300-ISMMS1 AHJ08020.1     1
 AYM13_12230   Staphylococcus aureus USA300-SUR1 AQQ84907.1     1
 AYM23_12290   Staphylococcus aureus USA300-SUR10 AQR11379.1     1
 AYM24_12290   Staphylococcus aureus USA300-SUR11 AQR14318.1     1
 AYM25_11970   Staphylococcus aureus USA300-SUR12 AQR17195.1     1
 AYM26_12300   Staphylococcus aureus USA300-SUR13 AQR20142.1     1
 AYM27_12305   Staphylococcus aureus USA300-SUR14 AQR23082.1     1
 AYM28_12305   Staphylococcus aureus USA300-SUR15 AQR26024.1     1
 AYM29_12305   Staphylococcus aureus USA300-SUR16 AQR29012.1     1
 AYM30_12310   Staphylococcus aureus USA300-SUR17 AQR31960.1     1
 AYM31_12305   Staphylococcus aureus USA300-SUR18 AQR34904.1     1
 AYM32_12305   Staphylococcus aureus USA300-SUR19 AQR37853.1     1
 AYM14_12230   Staphylococcus aureus USA300-SUR2 AQQ87834.1     1
 AYM33_12280   Staphylococcus aureus USA300-SUR20 AQR40789.1     1
 AYM34_12295   Staphylococcus aureus USA300-SUR21 AQR43727.1     1
 AYM35_12270   Staphylococcus aureus USA300-SUR22 AQR46665.1     1
 AYM36_12270   Staphylococcus aureus USA300-SUR23 AQR49601.1     1
 AYM37_12305   Staphylococcus aureus USA300-SUR24 AQR52543.1     1
 AYM15_12300   Staphylococcus aureus USA300-SUR3 AQQ90776.1     1
 AYM16_12290   Staphylococcus aureus USA300-SUR4 AQQ93711.1     1
 AYM18_12290   Staphylococcus aureus USA300-SUR5 AQQ96650.1     1
 AYM19_12295   Staphylococcus aureus USA300-SUR6 AQQ99593.1     1
 AYM20_12300   Staphylococcus aureus USA300-SUR7 AQR02557.1     1
 AYM21_12290   Staphylococcus aureus USA300-SUR8 AQR05494.1     1
 AYM22_12290   Staphylococcus aureus USA300-SUR9 AQR08440.1     1
 EP20_011105   Staphylococcus aureus V2200 ALK42585.1     1
 ASL17_13125   Staphylococcus aureus V521 AND37019.1     1
 ASL18_13125   Staphylococcus aureus V605 AND45683.1     1
 SAXN108_2455   Staphylococcus aureus XN108 AID40896.1     1
 AB179_11745   Staphylococcus aureus ZJ5499 AND03453.1     1
 SHYC_11715 (HysA)   Staphylococcus hyicus ATCC 11249 AJC97044.1     1
 SZO_06680   Steptococcus equi subsp. zooepidemicus H70 CAW98747.1     1
 Smon_0125   Streptobacillus moniliformis DSM 12112 ACZ00618.1 D1AWE2  
 Smon_0117 (fragment)   Streptobacillus moniliformis DSM 12112 ACZ00610.1 D1AWD4  
 SA111_01368 (HylB)   Streptococcus agalactiae CZT39479.1     1
 BQ8897_BM110_01288 (HylB)   Streptococcus agalactiae SIW57730.1     1
 BSA_12760   Streptococcus agalactiae 09mas018883 CCW38045.1     1
 V193_05585   Streptococcus agalactiae 138P AHN30604.1     1
 DN94_05585   Streptococcus agalactiae 138spar AHX75150.1     1
 GBS222_1026 (HylB)   Streptococcus agalactiae 2-22 CCO74748.1     1
 SAG1197   Streptococcus agalactiae 2603V/R AAN00079.1
NP_688206.1
    1
 hyaluronate lyase (HylB) 4.2.2.1 Streptococcus agalactiae 4755 CAA75865.1 O86478   1
 CHF17_01286   Streptococcus agalactiae 874391 ASZ01543.1     1
 SAK_1284 (HylB)   Streptococcus agalactiae A909 ABA45106.1     1
 GT95_06720   Streptococcus agalactiae C001 ASI66297.1     1
 GBSCOH1_1103   Streptococcus agalactiae COH1 CDN66569.1     1
 BB161_06890   Streptococcus agalactiae CUGBS591 ASA79900.1     1
 CUGBS08_01230 (HylB)   Streptococcus agalactiae CU_GBS_08 AMQ14781.1     1
 CUGBS98_01167 (HylB)   Streptococcus agalactiae CU_GBS_98 AMQ16773.1     1
 A6J82_06845   Streptococcus agalactiae FDAARGOS_254 ARC45071.1     1
 A9256_06185   Streptococcus agalactiae FWL1402 ANR97234.1     1
 AOY37_06410   Streptococcus agalactiae GBS ST-1 ALP87742.1     1
 DK41_06360   Streptococcus agalactiae GBS1-NY AIK71752.1     1
 DK42_06655   Streptococcus agalactiae GBS2-NM AIK73870.1     1
 DX05_06680   Streptococcus agalactiae GBS6 AIK75919.1     1
 GBS85147_1176   Streptococcus agalactiae GBS85147 AKI57601.1     1
 A964_1170   Streptococcus agalactiae GD201008-001 AFS45935.1     1
 GX026_05610   Streptococcus agalactiae GX026 AKU01911.1     1
 GX064_06035   Streptococcus agalactiae GX064 AKU00152.1     1
 SAH002_06140 (fragment)   Streptococcus agalactiae H002 AKU03714.1    
 SAHN016_06120   Streptococcus agalactiae HN016 AKT96278.1     1
 MSA_13200 (fragment)   Streptococcus agalactiae ILRI005 CCW40178.1     1
 SAIL_13150   Streptococcus agalactiae ILRI112 CCW42329.1     1
 hyaluronate lyase (HylB;SaHyl;Gbs1270) 4.2.2.1 Streptococcus agalactiae NEM316 CAD46929.1
AAA56749.1
NP_735714.1
Q53591 1F1S[A]
1I8Q[A]
1LXM[A]
1
 EN72_06630   Streptococcus agalactiae NGBS061 AIF86754.1     1
 AMM49_06240   Streptococcus agalactiae NGBS128 AMD32505.1     1
 AMR84_06675   Streptococcus agalactiae NGBS357 AOF51244.1     1
 EN73_06165   Streptococcus agalactiae NGBS572 AIF88771.1     1
 BTH44_05635   Streptococcus agalactiae S13 APO41878.1     1
 A9J19_05590   Streptococcus agalactiae S25 ANI27449.1     1
 SaSA20_1016 (HylB)   Streptococcus agalactiae SA20-06 AFV72474.1     1
 B2G84_06620 (fragment)   Streptococcus agalactiae Sag158 AQY26557.1    
 B1H24_06860   Streptococcus agalactiae Sag37 AQY24485.1     1
 AMD29_06425   Streptococcus agalactiae SG-M1 ALB16210.1     1
 BB194_06520   Streptococcus agalactiae SG-M158 ASA84053.1     1
 BB197_06520   Streptococcus agalactiae SG-M163 ASA82000.1     1
 BB164_07095 (fragment)   Streptococcus agalactiae SG-M25 ASA90294.1    
 BB268_06520   Streptococcus agalactiae SG-M29 ASA88157.1     1
 BB165_06145   Streptococcus agalactiae SG-M4 ASA99110.1     1
 BB313_06515   Streptococcus agalactiae SG-M50 ASA86103.1     1
 BB162_06165   Streptococcus agalactiae SG-M6 ASA94416.1     1
 RDF_1194   Streptococcus agalactiae SS1 AKI95609.1     1
 hyaluronate lyase (Hyl) (fragment)   Streptococcus agalactiae VMC-57 AEV45786.1     1
 hyaluronate lyase, partial (HylB) (fragment)   Streptococcus agalactiae VMC17 AEV45782.1     1
 hyaluronate lyase (Hyl) (fragment)   Streptococcus agalactiae VMC31 AEV45787.1     1
 hyaluronate lyase (HylB) (fragment)   Streptococcus agalactiae VMC55 AEK20863.1     1
 hyaluronate lyase (HylB) (fragment)   Streptococcus agalactiae VMC90 AEL88241.1     1
 BBP08_02765   Streptococcus agalactiae WC1535 AOQ20231.1     1
 YM001_06060   Streptococcus agalactiae YM001 AKT98224.1     1
 SANR_1718   Streptococcus anginosus C238 AGU84133.1     1
 ORF   Streptococcus anginosus MAS624 AAQ73521.1 Q6W9E0   1
 ANG_0558   Streptococcus anginosus subsp. whileyi MAS624 BAN61028.1     1
 hyaluronate lyase 4.2.2.1 Streptococcus constellatus subsp. constellatus ATCC 27823 AAK67165.1 Q934I5   1
 ORF (partial)   Streptococcus constellatus subsp. constellatus C-19 AAQ73520.1    
 SCI_1642   Streptococcus constellatus subsp. pharyngis C1050 AGU80540.1     1
 SCRE_1598   Streptococcus constellatus subsp. pharyngis C232 AGU73395.1     1
 SCR2_1598   Streptococcus constellatus subsp. pharyngis C818 AGU75149.1     1
 ORF   Streptococcus constellatus subsp. pharyngis MM9889A AAQ73523.1 Q6W9D8   1
 SDSE167_0713 (HylB)   Streptococcus dysgalactiae subsp. equisimilis 167 BAN93105.1     1
 SDSE_0694 (HylB)   Streptococcus dysgalactiae subsp. equisimilis AC-2713 CCI62192.1     1
 SDE12394_03510   Streptococcus dysgalactiae subsp. equisimilis ATCC 12394 ADX24222.1     1
 SDEG_0654 (HylB)   Streptococcus dysgalactiae subsp. equisimilis GGS_124 BAH81156.1 C5WFJ1   1
 GGS_0628 (HylB)   Streptococcus dysgalactiae subsp. equisimilis RE378 BAM60784.1     1
 SE071780_01513   Streptococcus equi subsp. equi ATCC 39506 ASB97104.1     1
 hyaluronidase (Hyl)   Streptococcus equi subsp. zooepidemicus ACT33447.1 C7E667   1
 HylC   Streptococcus equi subsp. zooepidemicus 542 AHI46574.1     1
 HylC   Streptococcus equi subsp. zooepidemicus 8 AHI46573.1     1
 hyaluronidase   Streptococcus equi subsp. zooepidemicus ATCC 35246 ACH78324.1 B5TE63   1
 hyaluronate lyase (HylB)   Streptococcus equi subsp. zooepidemicus ATCC 39920 AHJ09603.1     1
 hyaluronidase (Hyl) 4.2.2.1 Streptococcus equi subsp. zooepidemicus CVCC23362 ABV69920.1 A8HJR5   1
 Q426_02630   Streptococcus equi subsp. zooepidemicus CY AIA68655.1     1
 hyaluronidase (HylB)   Streptococcus equi subsp. zooepidemicus E69 AFK73249.1     1
 hyaluronidase   Streptococcus equi subsp. zooepidemicus MF002 AKM20831.1     1
 Sez_1299   Streptococcus equi subsp. zooepidemicus MGCS10565 ACG62635.1 B4U3R8   1
 hyaluronidase (HylB)   Streptococcus equi subsp. zooepidemicus NC88 AFK73248.1     1
 BMF34_01220   Streptococcus iniae 89353 APD31157.1     1
 CTW00_00807 (HylB)   Streptococcus iniae FP5228 ATX39008.1     1
 DQ08_01045   Streptococcus iniae ISET0901 AHY15097.1     1
 DW64_01040   Streptococcus iniae ISNO AHY16967.1     1
 QMA0248_0228 (HylB)   Streptococcus iniae QMA0248 ASL34076.1     1
 K710_0217   Streptococcus iniae SF1 AGM98022.1     1
 SI82_01295   Streptococcus iniae YSFST01-82 AJG25283.1     1
 hyaluronate lyase 4.2.2.1 Streptococcus intermedius ATCC 27335 AAK67167.1 Q934I4   1
 SIR_1547   Streptococcus intermedius B196 AGU76898.1     1
 SII_1533   Streptococcus intermedius C270 AGU78697.1     1
 A6J72_07395   Streptococcus intermedius FDAARGOS_233 ARC27012.1     1
 SCIM_1362   Streptococcus intermedius JTH08 BAM24016.1     1
 RN88_07180   Streptococcus intermedius KCOM 1545 ALF28283.1     1
 SITYG_16360   Streptococcus intermedius TYG1620 BAW17615.1     1
 SAMEA4412692_01386 (HylA)   Streptococcus merionis NCTC13788 SNU89167.1     1
 STP_1167   Streptococcus parauberis KCTC 11537 AEF25615.1     1
 Sequence 4843 from patent US 6800744   Streptococcus pneumoniae AAW09447.1
ABI03997.1
ABI09038.1
ABJ32554.1
ABJ50167.1
ABL17910.1
    1
 SP670_0382   Streptococcus pneumoniae 670-6B ADM90457.1 E0TRJ4   1
 SP70585_0379   Streptococcus pneumoniae 70585 ACO16655.1 C1CB94   1
 T308_01575   Streptococcus pneumoniae A026 AGZ47134.1     1
 A66_00307   Streptococcus pneumoniae A66 CRI61018.1     1
 SPAP_0347   Streptococcus pneumoniae AP200 ADM83940.1 E0SVG1   1
 SPN23F02890   Streptococcus pneumoniae ATCC 700669 CAR68147.1 B8ZL35   1
 SPCG_0322   Streptococcus pneumoniae CGSP14 ACB89574.1 B2ISN7   1
 SPND122_00329 (fragment)   Streptococcus pneumoniae D122 AOG55280.1     1
 SPND141_00331 (fragment)   Streptococcus pneumoniae D141 AOG57361.1     1
 SPD_0287   Streptococcus pneumoniae D39 ABJ54273.1 Q04ME3   1
 SPG_0285 (HyL)   Streptococcus pneumoniae G54 ACF54992.1 B5E6X4   1
 HMPREF1038_00364 (HysA)   Streptococcus pneumoniae gamPNI0373 AFS42440.1     1
 SPNHU15_00387   Streptococcus pneumoniae Hu15 ARD36199.1     1
 SPNHU17_00385   Streptococcus pneumoniae Hu17 ARD33999.1     1
 SPH_0426   Streptococcus pneumoniae Hungary19A-6 ACA36441.1 B1I936   1
 INV104_02610   Streptococcus pneumoniae INV104 CBW35945.1 E1XPE8   1
 SPNINV200_02820   Streptococcus pneumoniae INV200 CBW33916.1 E1XHX5   1
 SPJ_0310   Streptococcus pneumoniae JJA ACO18875.1 C1CC91   1
 KK0381_20060 (fragment)   Streptococcus pneumoniae KK0381 BAX32126.1     1
 KK0981_23420 (fragment)   Streptococcus pneumoniae KK0981 BAW83838.1     1
 KK1157_21240 (fragment)   Streptococcus pneumoniae KK1157 BAX34421.1     1
 MDRSPN_00289 (HysA)   Streptococcus pneumoniae MDRSPN001 BBA58495.1     1
 ERS445053_00184   Streptococcus pneumoniae NCTC7465 COT00131.1     1
 SpnNT_00308 (fragment)   Streptococcus pneumoniae NT_110_58 AJD71249.1     1
 SPP_0350   Streptococcus pneumoniae P1031 ACO21275.1 C1CII1   1
 hyaluronate lyase (HysA) 4.2.2.1 Streptococcus pneumoniae R6 AAK99090.1
AAA53685.1
AAA53686.1
AAT16666.1
ACK14456.1
ACW45175.1
NP_357880.1
Q8CWU3 1C82[A]
1EGU[A]
1F9G[A]
1LOH[A]
1LXK[A]
1N7N[A]
1N7O[A]
1N7P[A]
1N7Q[A]
1N7R[A]
1OJM[A]
1OJN[A]
1OJO[A]
1OJP[A]
1W3Y[A]
2BRP[A]
2BRV[X]
2BRW[A,B]
1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP004 AGI41259.1     1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP008 AGI41260.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP010 AGI41261.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP014 AGI41262.1     1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP015 AGI41263.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP017 AGI41264.1     1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP028 AGI41265.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP031 AGI41266.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP034 AGI41267.1     1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP035 AGI41268.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP036 AGI41269.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP037 AGI41270.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP038 AGI41271.1     1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP039 AGI41272.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP041 AGI41273.1     1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP043 AGI41274.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP044 AGI41275.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP066 AGI41276.1     1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP072 AGI41277.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP074 AGI41278.1     1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP089 AGI41279.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP090 AGI41280.1     1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP091 AGI41281.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP092 AGI41282.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP094 AGI41283.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP096 AGI41284.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP098 AGI41285.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP100 AGI41286.1     1
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP102 AGI41287.1     1
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP103 AGI41288.1     1
 BMJ42_00426   Streptococcus pneumoniae SP49 APJ29761.1     1
 BOC71_00314 (fragment)   Streptococcus pneumoniae SP61 APJ31834.1     1
 BOC72_00314 (fragment)   Streptococcus pneumoniae SP64 APJ33859.1     1
 SPNA45_01722   Streptococcus pneumoniae SPNA45 CCM09007.1     1
 MYY_0397   Streptococcus pneumoniae ST556 AFC94059.1     1
 SPT_0364   Streptococcus pneumoniae Taiwan19F-14 ACO22630.1 C1CPJ1   1
 HMPREF0837_10617 (fragment)   Streptococcus pneumoniae TCH8431/19A ADI68845.1 D6ZQF6   1
 hyaluronate lyase (Hyl;SpHyl;SP0314) 4.2.2.1 Streptococcus pneumoniae TIGR4 AAK74491.1
NP_344851.1
Q54873   1
 hyaluronate lyase (HylA) 4.2.2.1 Streptococcus pyogenes AAF29533.1 Q9L7W9   1
 HylA   Streptococcus pyogenes 1020 ABU63951.1 A7XFV6   1
 HylA   Streptococcus pyogenes 1055 ABU63942.1 A7XFU7   1
 STAB904_04685   Streptococcus pyogenes 1E1 AIW11723.1     1
 HylA   Streptococcus pyogenes 2397 ABU63950.1 A7XFV5   1
 HylA   Streptococcus pyogenes 3200 ABU63939.1 A7XFU4   1
 HylA   Streptococcus pyogenes 350 ABU63943.1 A7XFU8   1
 HylA   Streptococcus pyogenes 3779 ABU63952.1 A7XFV7   1
 HylA   Streptococcus pyogenes 422 ABU63944.1 A7XFU9   1
 HylA   Streptococcus pyogenes 4282 ABU63947.1 A7XFV2   1
 HylA   Streptococcus pyogenes 4283 ABU63940.1 A7XFU5   1
 HylA   Streptococcus pyogenes 437 ABU63946.1 A7XFV1   1
 HylA   Streptococcus pyogenes 445 ABU63941.1 A7XFU6   1
 HylA   Streptococcus pyogenes 4786 ABU63945.1 A7XFV0   1
 SP5448_05785   Streptococcus pyogenes 5448 AKK70559.1     1
 HylA   Streptococcus pyogenes 6219 ABU63938.1 A7XFU3   1
 STAB1101_03670   Streptococcus pyogenes 7F7 AIT77407.1     1
 HylA   Streptococcus pyogenes 872 ABU63948.1 A7XFV3   1
 HylA   Streptococcus pyogenes 94146 ABU63949.1 A7XFV4   1
 A20_0798c   Streptococcus pyogenes A20 AFV37880.1     1
 SPYALAB49_000782   Streptococcus pyogenes Alab49 AEQ24382.1     1
 SPAP1_05845   Streptococcus pyogenes AP1 AKG28139.1     1
 AUQ45_0798 (HylA)   Streptococcus pyogenes AP53 AMY97358.1     1
 DP15_1805   Streptococcus pyogenes ATCC 19615 AIL10717.1     1
 SpyM6D471_03750   Streptococcus pyogenes D471 AKI77732.1     1
 AL510_09105   Streptococcus pyogenes FDAARGOS_149 AMH03994.1     1
 B2G65_05840   Streptococcus pyogenes GUR ASO74252.1     1
 CFA72_05840   Streptococcus pyogenes GURSA1 ASO68537.1     1
 SPYH293_00769 (HylA)   Streptococcus pyogenes H293 CDJ55020.1     1
 CRD75_03875   Streptococcus pyogenes HarveyGAS ATL56719.1     1
 HKU360_00822 (HylA)   Streptococcus pyogenes HKU360 AIW24640.1     1
 HKU488_00663   Streptococcus pyogenes HKU488 AKP81594.1     1
 L897_03945   Streptococcus pyogenes HSC5 AGQ28489.1     1
 JMUB1235_0791 (HylA)   Streptococcus pyogenes JMUB1235 BAV55046.1     1
 SPYJRS4_0767 (HylA)   Streptococcus pyogenes JRS4 BAR44267.1
AKI76061.1
    1
 M1GAS476_0819 (HylA)   Streptococcus pyogenes M1 476 BAM30149.1     1
 SPY1032 (HylA)   Streptococcus pyogenes M1 GAS AAK33924.1
NP_269203.1
Q99ZX4   1
 FE90_0855 (HylA)   Streptococcus pyogenes M23ND AIQ01620.1     1
 ABO05_05685   Streptococcus pyogenes M28PF1 AKJ92769.1     1
 M3B_1287   Streptococcus pyogenes M3-b BAU60656.1     1
 AWM59_05560   Streptococcus pyogenes MEW123 AMA70697.1     1
 AWM58_04040   Streptococcus pyogenes MEW427 AMA68852.1     1
 MGAS10270_Spy0874 (HylA)   Streptococcus pyogenes MGAS10270 ABF33939.1 Q1JH55   1
 M6_Spy0782   Streptococcus pyogenes MGAS10394 AAT86917.1     1
 MGAS10750_Spy0909 (HylA)   Streptococcus pyogenes MGAS10750 ABF37859.1 Q1J6X4   1
 MGAS15252_0784 (HylA)   Streptococcus pyogenes MGAS15252 AFC66130.1     1
 MGAS1882_0780 (HylA)   Streptococcus pyogenes MGAS1882 AFC67994.1     1
 MGAS2096_Spy0831 + MGAS2096_Spy0830 (HylA)   Streptococcus pyogenes MGAS2096 ABF35882.1
ABF35883.1
    1
 MGAS23530_0756 (HylA)   Streptococcus pyogenes MGAS23530 ANC25438.1     1
 MGAS27061_0791 (HylA)   Streptococcus pyogenes MGAS27061 ANC27069.1     1
 HylA   Streptococcus pyogenes MGAS315 AAM79272.1
NP_664469.1
Q8K7S1   1
 M5005_Spy_0757 (HylA)   Streptococcus pyogenes MGAS5005 AAZ51375.1     1
 M28_Spy0736 (HylA)   Streptococcus pyogenes MGAS6180 AAX71849.1     1
 HylA   Streptococcus pyogenes MGAS8232 AAL97649.1
NP_607150.1
Q8P183   1
 MGAS9429_Spy0871 (HylA)   Streptococcus pyogenes MGAS9429 ABF32059.1 Q1JM10   1
 MTB313_0811   Streptococcus pyogenes MTB313 BAQ51219.1     1
 MTB314_0766   Streptococcus pyogenes MTB314 BAQ52931.1     1
 ERS445054_00836 (HylA)   Streptococcus pyogenes NCTC8198 CKG88530.1     1
 SD89_03820   Streptococcus pyogenes NGAS322 AKZ50245.1     1
 DK92_04920   Streptococcus pyogenes NGAS596 AKI37165.1     1
 SD90_03770   Streptococcus pyogenes NGAS638 AKZ52045.1     1
 DI45_05315   Streptococcus pyogenes NGAS743 AKI35429.1     1
 A4265_03810   Streptococcus pyogenes NS53 ANC74402.1     1
 Spy49_0811c (HylA)   Streptococcus pyogenes NZ131 ACI61121.1 B5XLA9   1
 SPs1188 (fragment)   Streptococcus pyogenes SSI-1 BAC64283.1
NP_802450.1
Q878K8  
 VT08_03755   Streptococcus pyogenes STAB09014 ANP29343.1     1
 VU19_03745   Streptococcus pyogenes STAB10015 AKL62955.1     1
 STAB1102_04135   Streptococcus pyogenes STAB1102 AIG48798.1     1
 AXK13_04410   Streptococcus pyogenes STAB13021 AND04811.1     1
 A6J68_07690   Streptococcus sp. group B FDAARGOS_229 ARC25048.1     1
 hyaluronidase (HylA)   Streptococcus suis CAG27053.1 Q6H8Y0   1
 hyaluronidase (HylA)   Streptococcus suis CAG27052.1 Q6H8Y1   1
 HylA (fragment)   Streptococcus suis CAC87664.1
ADF49630.1
Q8VLQ6   1
 hyaluronidase (HylA) (fragment)   Streptococcus suis CAG27068.1 Q6A1P9   1
 HAS68_04750   Streptococcus suis 05HAS68 AHF59038.1     1
 SSU05_1215 + SSU05_1214 (fragment)   Streptococcus suis 05ZYH33 ABP90180.1
ABP90181.1
    1
 hyaluronate lyase (HylA)   Streptococcus suis 1043248 AKC34794.1     1
 hyaluronate lyase (HylA)   Streptococcus suis 1097205 AKC34795.1     1
 ID09_06430   Streptococcus suis 6407 AIG43680.1     1
 AN924_01090   Streptococcus suis 90-1330 AMU78672.1     1
 hyaluronidase (HylA) (fragment)   Streptococcus suis 98015 ABD74496.1 Q8VLQ6   1
 SSU98_1230 + SSU98_1229 (fragment)   Streptococcus suis 98HAH33 ABP92387.1
ABP92388.1
    1
 SSUA7_1065 (fragment)   Streptococcus suis A7 AER44387.1     1
 SSUA7_1066 (fragment)   Streptococcus suis A7 AER44388.1     1
 hyaluronidase (HylA) (fragment)   Streptococcus suis CVCC606 ABP35951.1 Q8VLQ6   1
 hyaluronidase (HylA) (fragment)   Streptococcus suis CVCC607 ABP35952.1 A4ZX85   1
 SSUD9_1371   Streptococcus suis D9 AER17555.1     1
 hyaluronate lyase (HylA) (fragment)   Streptococcus suis DAT229 AKC34791.1     1
 hyaluronate lyase (HylA) (fragment)   Streptococcus suis DAT261 AKC34790.1     1
 A6M16_03715   Streptococcus suis DN13 ANC99638.1     1
 BFP66_03605   Streptococcus suis GZ0565 AOM74360.1     1
 SSGZ1_1070 (fragment)   Streptococcus suis GZ1 ADE31527.1 D5AI62   1
 SSGZ1_1071 (fragment)   Streptococcus suis GZ1 ADE31528.1 D5AI63   1
 hyaluronidase   Streptococcus suis HA1001111 ADO66679.1 E3UN55   1
 hyaluronidase   Streptococcus suis HA1001112 ADO66680.1 E3UN56   1
 hyaluronidase (HylA) (fragment)   Streptococcus suis HA9801 ADC54170.1 D3K641  
 hyaluronidase (HylA) (fragment)   Streptococcus suis JR0507 ADF49631.1 D5LKE5  
 SSUJS14_1182 + SSUJS14_1181 (fragment)   Streptococcus suis JS14 ADV70253.1
ADV70254.1
    1
 A9494_05630 (fragment)   Streptococcus suis LSM102 ARX90495.1     1
 A9494_05625 (fragment)   Streptococcus suis LSM102 ARX90494.1     1
 hyaluronate lyase (HylA) (fragment)   Streptococcus suis MGGUS2 AKC34789.1     1
 hyaluronate lyase (HylA)   Streptococcus suis MGGUS5 AKC34796.1     1
 hyaluronate lyase (HylA)   Streptococcus suis MGGUS9 AKC34799.1     1
 hyaluronate lyase (HylA) (fragment)   Streptococcus suis MNCM01 AKC34787.1     1
 hyaluronate lyase (HylA)   Streptococcus suis MNCM04 AKC34797.1     1
 hyaluronate lyase (HylA) (fragment)   Streptococcus suis MNCM16 AKC34788.1     1
 hyaluronate lyase (HylA)   Streptococcus suis MNCM43 AKC34798.1     1
 AA105_07005   Streptococcus suis NSUI002 ALA28993.1     1
 APQ97_06125   Streptococcus suis NSUI060 AML46650.1     1
 hyaluronate lyase (HylA) (fragment)   Streptococcus suis P1/7 AKC34785.1     1
 hyaluronate lyase (HylA) (fragment)   Streptococcus suis P477/03P1 AKC34793.1     1
 HylA 4.2.2.1 Streptococcus suis P5/11/88 CAC87663.1 Q8VLQ7   1
 hyaluronate lyase (HylA) (fragment)   Streptococcus suis P517/03P4 AKC34792.1     1
 YYK_05005 (HylA) (fragment)   Streptococcus suis S735 AFR00520.1
AKC34786.1
    1
 NJAUSS_1122 (fragment)   Streptococcus suis SC070731 AGG64591.1     1
 NJAUSS_1123 (fragment)   Streptococcus suis SC070731 AGG64592.1    
 hyaluronidase (HylA) (fragment)   Streptococcus suis SC152 ABD74495.1 Q8VLQ6   1
 hyaluronidase (HylA) (fragment)   Streptococcus suis SC17 ABD74493.1 Q8VLQ6   1
 B9H01_05865 (fragment)   Streptococcus suis SC19 ARL70058.1     1
 B9H01_05870 (fragment)   Streptococcus suis SC19 ARL70059.1     1
 hyaluronidase (HylA) (fragment)   Streptococcus suis SC22 ABD74494.1 Q8VLQ6   1
 hyaluronidase (HylA)   Streptococcus suis SEROTYPE 2 CAG27049.1
CAG27048.1
Q6H8Y3
Q6H8Y4
  1
 hyaluronidase (HylA)   Streptococcus suis SEROTYPE 2 CAG27050.1 Q6H8Y2
Q6H8Y4
  1
 hyaluronidase (HylA) 4.2.2.1 Streptococcus suis SEROTYPE 7 CAC87662.1 Q8VLQ8   1
 SSU12_1118 (fragment)   Streptococcus suis SS12 AER15299.1     1
 hyaluronidase (HylA) (fragment)   Streptococcus suis SS2-1 ADC54171.1    
 SSUST1_0748   Streptococcus suis ST1 AER21132.1     1
 SSUST3_1226   Streptococcus suis ST3 AEB81651.1     1
 T15_0747   Streptococcus suis T15 AGZ22850.1     1
 YB51_6050   Streptococcus suis YB51 AGW87582.1     1
 ZY05719_05815 (fragment)   Streptococcus suis ZY05719 AKG40504.1     1
 ZY05719_05810 (fragment)   Streptococcus suis ZY05719 AKG40503.1     1
 SMD11_2031   Streptomyces albireticuli SMD11 ARZ67683.1    
 SMD44_01144   Streptomyces alboflavus MDJK44 ARX81746.1    
 SMD44_08331   Streptomyces alboflavus MDJK44 ARX88844.1    
 DC74_5664   Streptomyces albulus NK660 AIA06116.1    
 SAZ_29920   Streptomyces albulus ZPM AKA06207.1    
 SLNHY_4652   Streptomyces albus BK3-25 AOU79343.1    
 SLNWT_4661   Streptomyces albus DSM 41398 AJE85037.1    
 SAM23877_5289   Streptomyces ambofaciens ATCC 23877 AKZ58334.1    
 SAM40697_4788   Streptomyces ambofaciens DSM 40697 ANB08745.1    
 BV401_05635   Streptomyces autolyticus CGMCC0516 AQA10055.1    
 SAV2704   Streptomyces avermitilis MA-4680 = NBRC 14893 BAC70415.1
NP_823880.1
   
 SBI_01112   Streptomyces bingchenggensis BCW-1 ADI04233.1 D7C872  
 SCAT_4363   Streptomyces cattleya NRRL 8057 = DSM 46488 CCB77059.1    
 SCATT_43510   Streptomyces cattleya NRRL 8057 = DSM 46488 AEW96722.1    
 BB341_06495   Streptomyces clavuligerus F613-1 ANW17892.1    
 hyaluronate lyase (PL8Hyal;SCO5534;SC1C2.15) 4.2.2.1 Streptomyces coelicolor A3(2) CAA19982.1
NP_629668.1
O86516 2WCO[A]
2WDA[A]
2X03[A,B]
 B446_25985   Streptomyces collinus Tu 365 AGS72005.1    
 TU94_23365   Streptomyces cyaneogriseus subsp. noncyanogenus NMWT 1 AJP05849.1    
 BN159_2862   Streptomyces davawensis JCM 4913 CCK27241.1    
 BN159_0958   Streptomyces davawensis JCM 4913 CCK25337.1    
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