Activities in Sub Family	Chondroitinase B (EC 4.2.2.19); Chondroitin AC lyase (EC 4.2.2.5); Heparin lyase / heparin lyase I (EC 4.2.2.7);
Mechanism	b-elimination
3D Structure Status	( α / α ) 6 toroid + anti-parallel β-sheet
Commercial Enzyme Provider(s)	MEGAZYME; PROZOMIX;
Statistics	GenBank accession (995); Uniprot accession (5); PDB accession (7); 3D entries (3); cryst (1)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)	Subf
chondroitin sulfate ABC lyase	4.2.2.19 4.2.2.5	Bacteroides thetaiotaomicron WAL2926	ABV21364.1	C5G6D7	2Q1F[A,B] 2.85	2
chondroitin ABC lyase I / chondroitinase ABC (ChABC)	4.2.2.19 4.2.2.5	Proteus vulgaris	2109195A ABE23097.1 ACN04689.1 ACQ12496.1 ACQ12497.1 ACW17440.1 ACW17441.1 ACY01450.1	P59807	1HN0[A] 1.90 7EIP[A] 1.88 7EIQ[A] α-L-4-deoxy-IdopA-(1-3)-β-D-GalpNAc4SO3 β-D-4-deoxy-GlcpA-(1-3)-β-D-GalpNAc4SO3 1.80 7EIR[A] α-L-4-deoxy-IdopA-(1-3)-β-D-GalpNAc6SO3 β-D-4-deoxy-GlcpA-(1-3)-β-D-GalpNAc6SO3 1.92 7EIS[A] α-L-4-deoxy-IdopA-(1-3)-β-D-GalpNAc β-D-4-deoxy-GlcpA-(1-3)-β-D-GalpNAc 2.50 7YKE[A] β-D-4-deoxy-GlcpA-(1-3)-β-D-GalpNAc4SO36SO3 1.88	2
chondroitin AC lyase II (ChACII)	4.2.2.5	Proteus vulgaris ATCC 6896	AAB43333.1 ABU46331.1	C7S340	cryst	2
Top

Last update: 2024-03-18 © Copyright 1998-2024
AFMB - CNRS - Université d'Aix-Marseille