Polysaccharide Lyase Family 7

Activities in Familypoly(β-mannuronate) lyase / M-specific alginate lyase (EC 4.2.2.3); α-L-guluronate lyase / G-specific alginate lyase (EC 4.2.2.11); poly-(MG)-lyase / MG-specific alginate lyase (EC 4.2.2.-); endo-β-1,4-glucuronan lyase (EC 4.2.2.14); oligoalginate lyase / exo-alginate lyase (EC 4.2.2.26)
Mechanism b-elimination
3D Structure Statusβ-jelly roll
External resourcesCAZypedia;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (2649); Uniprot accession (46); PDB accession (27); 3D entries (13); cryst (0)
Bacteria
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D Subf
 alginate lyase (A1m;AlgL) 4.2.2.11
4.2.2.-
pubmed
pubmed
Agarivorans sp. JAM-A1m BAG70358.1 B5BSV2   5
 alkaline alginate lyase (Alyl1) 4.2.2.11 pubmed
Agarivorans sp. L11 AIY68670.1 A0A0A7EPH1  
 alginate lyase (AlyL2) 4.2.2.11
4.2.2.3
pubmed
pubmed
Agarivorans sp. L11 AJO61885.1
AIY68685.1
A0A0C5D0M6
A0A2R2N6C7
  5
 poly-MG alginate lyase (AlyA1;Avin_31810) 4.2.2.- pubmed
Azotobacter vinelandii DJ ATCC BAA-1303 ACO79344.1 C1DNZ1   1
 poly-MG alginate lyase (AlyA3;Avin_13810) (fragment) 4.2.2.- pubmed
Azotobacter vinelandii DJ ATCC BAA-1303 ACO77598.1 C1DQS5  
 poly-MG alginate lyase (AlyA2;Avin_23960) 4.2.2.- pubmed
Azotobacter vinelandii DJ ATCC BAA-1303 ACO78583.1 C1DHI8   1
 endo-β-1,4-glucuronan lyase (Caci_1606) 4.2.2.14 pubmed
Catenulispora acidiphila DSM 44928 ACU70527.1 C7QBF0   4
 poly(α-L-guluronate) lyase / G-specific alginate lyase (alyPG) 4.2.2.11 pubmed
Corynebacterium sp. ALY-1 BAA83339.1
ACK10589.1
Q9RB42 1UAI[A] 3
 alginate lyase (AlgB) 4.2.2.11 doi
Flammeovirga sp. NJ-04 ATJ01131.1 A0A291NNN1  
 alginate lyase 2A (Alg2A) 4.2.2.11 pubmed
Flavobacterium sp. S20 AEB69783.1 G9CHX6  
 alginate lyase (AlyA;FlAlyA) 4.2.2.3 pubmed
Flavobacterium sp. UMI-01 BAP05660.1 A0A068PC91 5Y33[A]
 poly(α-L-guluronate) lyase (AlyA) 4.2.2.11 pubmed
Klebsiella pneumoniae subsp. aerogenes AAA25049.1
ACK10577.1
Q59478 4OZX[A] 5
 alginate lyase (AlgMsp) 4.2.2.3 pubmed
Microbulbifer sp. 6532A BAJ62034.1 E7FLJ9   5
 alginate lyase SH7 (AlgSH7; GNX18_13395) 4.2.2.3 pubmed
Microbulbifer sp. SH-1 QIL91966.1
QID05195.1
    5
 alginate lyase (NitAly;NIS_0185) 4.2.2.3 pubmed
Nitratiruptor sp. SB155-2 BAF69299.1 A6Q1E0  
 alginate lyase (AlyQ) 4.2.2.3 pubmed
Persicobacter sp. CCB-QB2 WP_053404615.1 A0A3B6UEP6 5XNR[A] 3
 alginate lyase / poly-mannuronate lyase (AlxM) 4.2.2.3 pubmed
Photobacterium sp. ATCC 43367 CAA49630.1 P39049  
 alginate lyase (AlyPI) 4.2.2.11
4.2.2.3
pubmed
pubmed
Pseudoalteromonas sp. CY24 ACM89454.1 D0QMJ7   5
 poly-MG alginate lyase (PA1167) 4.2.2.- pubmed
Pseudomonas aeruginosa PAO1 AAG04556.1
NP_249858.1
Q9I4H0 1VAV[A,B] 1
 alginate lyase (alyC3) 4.2.2.3 pubmed
Psychromonas sp.   A0A7M4DUG8
A0A7M4DUG9
7C8F[B]
7C8G[A,B]
7C8F[A]
 alginate lyase / poly(β-mannuronate) lyase (Sde_2547) (Alg7D) 4.2.2.3 pubmed
Saccharophagus degradans 2-40 ABD81807.1
ACK10570.1
Q21HM2   5
 poly(α-L-guluronate) lyase / G-specific alginate lyase (A1-II';Aly) 4.2.2.11 pubmed
Sphingomonas sp. A1 BAD16656.1 Q75WP3 2CWS[A]
2Z42[A]
2ZA9[A]
2ZAA[A]
2ZAB[A]
2ZAC[A]
 bifunctional alginate lyase (aly;A1-I;A1-II_PolyG_PL7;A1-III_PolyM_PL5) 4.2.2.11 pubmed
Sphingomonas sp. A1 BAB03312.1
2009330A
Q9KWU1  
 alginate lyase (Alg) 4.2.2.11 pubmed
Streptomyces sp. ALG5 ABS59291.1 A7LFP7   3
 alginate lyase (Alg) 4.2.2.11 doi
Streptomyces sp. M3(2009) / M3 ACN56743.1 C0KWY1   3
 alginate lyase (AlyDW11) 4.2.2.3 pubmed
uncultured bacterium AEO50363.1 G3LI08   5
 alginate lyase (AlyVGII;AlyVG2) 4.2.2.11 pubmed
Vibrio halioticoli IAM14596T AAF22510.1 Q9RGQ5  
 poly(α-L-guluronate) lyase (AlyVGI;AlyVG1) 4.2.2.11 pubmed
Vibrio halioticoli IAM14596T AAF22512.1 Q9RGQ3   5
 alginate lyase / poly-mannuronate lyase (A9mT;Alg) 4.2.2.3 pubmed
Vibrio sp. A9m BAH79131.1 C4TJD2  
 alginate lyase / poly-mannuronate lyase (AlyVOB) 4.2.2.3 pubmed
Vibrio sp. O2 ABB36772.1 Q308B3  
 alginate lyase / poly-mannuronate lyase (AlyVOA) 4.2.2.3 pubmed
Vibrio sp. O2 ABB36771.1 Q308B4  
 alginate lyase (AlyVI) 4.2.2.11
4.2.2.3
pubmed
pubmed
Vibrio sp. QY101 AAP45155.1 Q53EJ1  
 alginate lyase (AlgB) 4.2.2.11
4.2.2.3
pubmed
pubmed
Vibrio sp. W13 AIY22661.1 A0A0A1DYR7  
 alginate lyase E (AlyE;V12B01_09446) 4.2.2.11
4.2.2.3
pubmed
pubmed
Vibrio splendidus 12B01 EAP94396.1 A3UT33   5
 alginate lyase A (AlyA;V12B01_24254) 4.2.2.3 pubmed
Vibrio splendidus 12B01 EAP94921.1 A3UR40  
 alginate lyase D (AlyD;V12B01_24274) 4.2.2.11
4.2.2.3
pubmed
pubmed
Vibrio splendidus 12B01 EAP94925.1 A3UR44   5
 Alginate lyase (Aly7B; AXE80_11190) 4.2.2.- pubmed
Wenyingzhuangia fucanilytica CZ1127 ANW96808.1
WP_068827319.1
A0A1B1Y7V0  
 exo-alginate lyase (AlyA5;zobellia_4131) 4.2.2.26 pubmed
Zobellia galactanivorans DsijT CAZ98266.1 G0L2Y1 4BE3[A,B] 5
 endo-guluronate lyase (AlyA1;zobellia_1182) 4.2.2.11 pubmed
Zobellia galactanivorans DsijT CAZ95239.1 G0LAE1 3ZPY[A,B] 3
Eukaryota
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D Subf
 alginate lyase (Aly;PyAly) 4.2.2.3 doi
Neopyropia yezoensis BAI66416.1
BAI66417.1
D2KX85  
 alginate lyase (PsAlg7A) 4.2.2.3 pubmed
Paradendryphiella salina VFY81779.1 A0A485PVH1 6YWF[A]
7NCZ[A]
7NL3[A]
7NM6[A]
7NPP[A]
7NY3[A]
7O6H[A]
7OOF[A]
 alginate lyase (PsAlg7C) 4.2.2.- pubmed
Paradendryphiella salina CAD6594633.1 A0A7I9C8Z1  
 alginate lyase (PsAlg7B) 4.2.2.- pubmed
Paradendryphiella salina CAD6594632.1 A0A7I9C7R9  
 endo-β-1,4-glucuronan lyase (TpPL7A; A9Z42_0012760) 4.2.2.14 pubmed
Trichoderma parareesei OTA00986.1   7NDE[A] 4
 endo-β-1,4-glucuronan lyase (TpPL7B; A9Z42_0015990) 4.2.2.14 pubmed
Trichoderma parareesei OTA01262.1     4
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