Activities in Family	Alginate lyase (EC 4.2.2.-); Poly-(MG)-lyase / MG-specific alginate lyase (EC 4.2.2.-); Poly(α-L-guluronate) lyase / G-specific alginate lyase (EC 4.2.2.11); Endo-β-1,4-glucuronan lyase (EC 4.2.2.14); Oligoalginate lyase / exo-alginate lyase (EC 4.2.2.26); Poly(β-mannuronate) lyase / M-specific alginate lyase (EC 4.2.2.3);
Mechanism	b-elimination
3D Structure Status	β-jelly roll
External resources	CAZypedia;
Commercial Enzyme Provider(s)	MEGAZYME;
Statistics	GenBank accession (3472); Uniprot accession (49); PDB accession (51); 3D entries (16); cryst (0)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
FG167_06580		Lacinutrix sp. WUR7	QRM88914.1			5
FG167_06595		Lacinutrix sp. WUR7	QRM88916.1			5
FG167_06545		Lacinutrix sp. WUR7	QRM88907.1
BWR22_11800		Lacinutrix venerupis DOK2-8	APY00961.1
BWR22_11850		Lacinutrix venerupis DOK2-8	APY00970.1			5
BWR22_11865		Lacinutrix venerupis DOK2-8	APY00973.1
BWR22_11835		Lacinutrix venerupis DOK2-8	APY00967.1			5
J4558_04550 (fragment)		Leptolyngbya sp. 15MV	QYU69420.1
Pla8534_06450 (AlyA)		Lignipirellula cremea Pla85_3_4	QDU92872.1			3
T8T21_17050		Limimaricola variabilis OXR-209	WPY96216.1			5
VV02_03535		Luteipulveratus mongoliensis MN07-A0370	AKU15153.1			3
Alginate Lyase, partial		Lutibacter agarilyticus AL94	QGZ98598.1
MKD41_09445		Lutibacter sp. A64	UMB52563.1
MKD41_04980		Lutibacter sp. A64	UMB54826.1
MHL31_08700		Lutibacter sp. A80	UMB59159.1
MHL31_04100		Lutibacter sp. A80	UMB61391.1
QZH61_02220		Lutimonas sp. YSD2104	WKK66446.1
QZH61_02225		Lutimonas sp. YSD2104	WKK66447.1
alginate lyase SHA-1		Mangrovibacterium sp. SH-52	QTF98059.1			5
BTR34_17225		Maribacter hydrothermalis T28	APQ18955.1			5
BTR34_05355		Maribacter hydrothermalis T28	APQ16779.1			5
YQ22_18270		Maribacter sp. 1_2014MBL_MicDiv	APA66084.1
YQ22_16235		Maribacter sp. 1_2014MBL_MicDiv	APA65724.1			5
YQ22_04520		Maribacter sp. 1_2014MBL_MicDiv	APA63643.1
YQ22_17225		Maribacter sp. 1_2014MBL_MicDiv	APA65898.1			5
YQ22_04515		Maribacter sp. 1_2014MBL_MicDiv	APA66273.1
QSV08_05845		Maribacter sp. BPC-D8	WRI30764.1			5
QSV08_20150		Maribacter sp. BPC-D8	WRI29516.1
QSV08_20155		Maribacter sp. BPC-D8	WRI29517.1
QSV08_19335		Maribacter sp. BPC-D8	WRI29360.1			5
SAMN05192545_0240		Maribacter sp. MAR_2009_60	SDR82856.1
SAMN05192545_0241		Maribacter sp. MAR_2009_60	SDR82911.1
SAMN05192545_1704		Maribacter sp. MAR_2009_60	SDS60794.1			5
SAMN05192545_1464		Maribacter sp. MAR_2009_60	SDS47394.1			5
SAMN05192545_1241		Maribacter sp. MAR_2009_60	SDS35186.1
MARGE09_P0151		Marinagarivorans cellulosilyticus GE09	BCD95952.1
CJ739_3051		Mariniflexile sp. TRM1-10	AXP82114.1
alginate lyase (AlgH)		Marinimicrobium sp. H1	QGU34249.1			5
G5B37_04065		Marinirhabdus gelatinilytica RR4-40	QIE58763.1			5
ONZ50_01490		Marinomonas sp. GJ51-6	WOD07874.1			5
ONZ50_17000		Marinomonas sp. GJ51-6	WOD07267.1
ONZ50_16675		Marinomonas sp. GJ51-6	WOD07217.1			5
MALG_02966		Marinovum algicola DG 898	AKO98116.1			5
AZF01_06880		Martelella sp. AD-3	AMM84112.1
MEBOL_001822		Melittangium boletus DSM 14713	ATB28376.1			3
MEBOL_005098		Melittangium boletus DSM 14713	ATB31635.1
Mag101_00390		Microbulbifer agarilyticus GP101	AQQ66277.1			5
Mag101_17615		Microbulbifer agarilyticus GP101	AQQ69248.1			5
Mag101_07840		Microbulbifer agarilyticus GP101	AQQ67563.1
Mag101_07840		Microbulbifer agarilyticus GP101	AQQ67563.1
PVT68_15560		Microbulbifer bruguierae H12	WGL16177.1			5
PVT68_15555 (fragment)		Microbulbifer bruguierae H12	WGL16176.1			5
alginate lyase (AlgMsp)	4.2.2.3	Microbulbifer sp. 6532A	BAJ62034.1	E7FLJ9		5
AlgL7		Microbulbifer sp. ALW1	UNJ85018.1			5
alginate lyase (fragment)		Microbulbifer sp. BY17	ARV76517.1			5
alginate lyase SH7 (AlgSH7; GNX18_13395)	4.2.2.3	Microbulbifer sp. SH-1	QIL91966.1 QID05195.1	A0A6G6A8R0 A0A6G8DJQ8		5
HUW35_08470		Microbulbifer sp. YPW1	QKX18972.1			5
A3224_00395		Microbulbifer thermotolerans DAU221	AMX01240.1			5
A3224_00385		Microbulbifer thermotolerans DAU221	AMX03967.1			5
alginate lyase		Microbulbifer thermotolerans DAU221	QLF98434.1			5
(G-specific) alginate lyase (Algt; SAMN05660479_01406)	4.2.2.11	Microbulbifer thermotolerans DSM 19189	SFC22205.1 WP_231902423.1			5
Q2E61_00390		Microbulbifer thermotolerans HB226069	WKT60689.1			5
Q2E61_00385		Microbulbifer thermotolerans HB226069	WKT60688.1			5
GA0070611_2471		Micromonospora auratinigra DSM 44815	SBT43818.1			3
GA0070618_1442		Micromonospora echinospora DSM 43816	SCE85913.1			3
GCM10017556_31310		Micromonospora sagamiensis JCM 3310	BCL15392.1			3
O7622_15475		Micromonospora sp. WMMD1076	WFF09851.1			3
JO965_20970		Microvirga sp. VF16	QRM28673.1
HPT29_015640		Microvirga terrae R24	UVF17948.1
HPT29_020355		Microvirga terrae R24	UVF18812.1
L0P88_12940		Muricauda sp. SCSIO 64092	UOY04858.1
L0P88_12935		Muricauda sp. SCSIO 64092	UOY04857.1
C3L23_05990		Nautilia profundicola PV-1	AZV46836.1
Niako_5220		Niastella koreensis GR20-10	AEW01457.1			3
alginate lyase (NitAly;NIS_0185)	4.2.2.3	Nitratiruptor sp. SB155-2	BAF69299.1	A6Q1E0
DDD_0347		Nonlabens dokdonensis DSW-6	AGC75474.1
R1T42_07280		Nonlabens ulvanivorans CI.11.F.A3	WOI21486.1
R1T42_05330		Nonlabens ulvanivorans CI.11.F.A3	WOI23879.1			5
NIES4070_06890 (AlyA)		Nostoc commune HK-02 NIES-4070	BBD64346.1
COO91_01694		Nostoc flagelliforme CCNUN1	AUB35803.1
GXM_00030		Nostoc sphaeroides CCNUC1	QFS42557.1
DZC78_07850		Olleya aquimaris DAU311	AXO80301.1			5
DZC78_00555		Olleya aquimaris DAU311	AXO78938.1			5
DZC78_02420		Olleya aquimaris DAU311	AXO79277.1			5
DZC78_07860		Olleya aquimaris DAU311	AXO80303.1
CW732_00385		Olleya sp. Bg11-27	AUC74216.1
CW732_00330		Olleya sp. Bg11-27	AUC74206.1
CW732_12185		Olleya sp. Bg11-27	AUC76381.1			5
CW732_11185		Olleya sp. Bg11-27	AUC76197.1			5
CW732_08740		Olleya sp. Bg11-27	AUC75757.1
H0I26_08400		Olleya sp. HaHaR_3_96	QXP61635.1
H0I26_12095		Olleya sp. HaHaR_3_96	QXP58653.1			5
H0I26_11090		Olleya sp. HaHaR_3_96	QXP58465.1			5
E6C60_2668		Paenibacillus algicola HB172198	QCT03380.1			5
D5F53_03260		Paenibacillus lautus E7593-69	AYB42356.1			5
AlgM		Paenibacillus sp. 8-5	AFF61390.1			5
P0X86_27635 (fragment)		Paenibacillus sp. BR1-192	WFB57696.1			5
P0X86_27630 (fragment)		Paenibacillus sp. BR1-192	WFB57695.1			5
JNUCC32_30170		Paenibacillus sp. JNUCC32	QOT10300.1			5
MJB10_22430		Paenibacillus sp. MBLB1832	WNR43826.1
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