Polysaccharide Lyase Family 38

Activities in FamilyExo-β-1,4-glucuronan lyase (EC 4.2.2.-);
Poly-(MG)-lyase / MG-specific alginate lyase (EC 4.2.2.-);
Poly(α-L-guluronate) lyase / G-specific alginate lyase (EC;
Endo-β-1,4-glucuronan lyase (EC;
Poly(β-mannuronate) lyase / M-specific alginate lyase (EC;
Mechanism b-elimination
3D Structure Status( α / α ) 7 barrel
NoteFamily created after Kikuchi & Konno et al., 2019 [PMID= 31546007] who have shown that the endo-b-1,4-glucuronan lyase activity of the SH203_01541 protein in Brevundimonas sp. SH203; very distant relatedness to PL5
Statistics GenBank accession (1821); Uniprot accession (2); PDB accession (3); 3D entries (2); cryst (0)
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 Bovatus_00170   Bacteroides ovatus ATCC 8483 ALJ44842.1  
3NFV[A] 1.95
3NNB[A] 1.60
 MG-specific alginate lyase (BoPL38;OU990_24705) 4.2.2.- Bacteroides ovatus CP926 WII03607.1  
8BDQ[A,B,C,D] 2.11

Last update: 2023-12-08 © Copyright 1998-2023
AFMB - CNRS - Université d'Aix-Marseille