| Activities in Family | Exo-β-1,4-glucuronan lyase (EC 4.2.2.-); Poly-(MG)-lyase / MG-specific alginate lyase (EC 4.2.2.-); Poly(α-L-guluronate) lyase / G-specific alginate lyase (EC 4.2.2.11); Endo-β-1,4-glucuronan lyase (EC 4.2.2.14); Poly(β-mannuronate) lyase / M-specific alginate lyase (EC 4.2.2.3); |
|---|---|
| Mechanism | b-elimination |
| 3D Structure Status | ( α / α ) 7 barrel |
| Note | Family created after Kikuchi & Konno et al., 2019 [PMID= 31546007] who have shown that the endo-b-1,4-glucuronan lyase activity of the SH203_01541 protein in Brevundimonas sp. SH203; very distant relatedness to PL5 |
| Statistics | GenBank accession (1876); Uniprot accession (2); PDB accession (3); 3D entries (2); cryst (0) |
| Bacteria | |||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | |
| alginate lyase 38A (Aly38A; LQZ07_11395) | 4.2.2.11 4.2.2.3 |
pubmed pubmed |
Agarivorans sp. B2Z047 | UQN45040.1 | |||
| MG-specific alginate lyase (BoPL38; OU990_24705) | 4.2.2.- | pubmed |
Bacteroides ovatus CP926 | WII03607.1 | 8BDQ[A,B,C,D] | ||
| endo-β-1,4-glucuronan lyase / cellouronate lyase (CUL-I; SH203_01541) | 4.2.2.14 | pubmed |
Brevundimonas sp. SH203 | GAW41138.1 WP_087120298.1 |
A0A1V1UZ54 | ||
| Eukaryota | |||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | |
| exo-β-1,4-glucuronan lyase (TpPL38A; A9Z42_0069930) | 4.2.2.- | pubmed |
Trichoderma parareesei | OTA06285.1 | A0A2H3A0K5 | ||
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