Activities in Family	Hyaluronate lyase (EC 4.2.2.1); Gellan lyase (EC 4.2.2.25); Chondroitin AC lyase (EC 4.2.2.5);
Mechanism	b-elimination
Note	This family groups together polysaccharide lyases active on hyaluronan, gellan and chondroitin sulfate (Helbert et al., PNAS (2019) [PMID=30850540])
Statistics	GenBank accession (1051); Uniprot accession (5);

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
AYX22_19165		Arthrobacter sp. D5-1	QSZ51149.1			1
LFT48_18135		Arthrobacter sp. FW305-123	UKA49332.1			1
OUO20_15390		Arthrobacter sp. FX8	WAJ32499.1			1
GC088_01355		Arthrobacter sp. JZ12	WRH23897.1			1
NicSoilB11_37030		Arthrobacter sp. NicSoilB11	BCW77378.1			1
NtRootA1_42440		Arthrobacter sp. NtRootA1	BCW08106.1			1
NtRootA9_34780		Arthrobacter sp. NtRootA9	BCW20770.1			1
StoSoilB20_37410		Arthrobacter sp. StoSoilB20	BCW60394.1			1
StoSoilB22_35940		Arthrobacter sp. StoSoilB22	BCW64621.1			1
CGK93_20065		Arthrobacter sp. YN	ASN22595.1			1
CEF21_16330		Bacillus sp. FJAT-42376	AZB43752.1			2
DOE78_11120		Bacillus sp. Y1	AYA75946.1			2
CGC64_02895		Bacteroides caccae ATCC 43185	ASM65007.1			2
CGC64_09415		Bacteroides caccae ATCC 43185	ASM66150.1			1
CGC64_08420		Bacteroides caccae ATCC 43185	ASM65982.1			1
NQ555_02855		Bacteroides caccae ATCC 43185	UWN79112.1			2
NQ555_09270		Bacteroides caccae ATCC 43185	UWN76916.1			1
NQ555_08285		Bacteroides caccae ATCC 43185	UWN80129.1			1
K6V29_01615		Bacteroides caccae BFG-100	UBF13151.1			1
K6V29_16500		Bacteroides caccae BFG-100	UBF12092.1			2
NXX85_05880		Bacteroides caccae BFG-101	UVP82737.1			2
NXX85_09970		Bacteroides caccae BFG-101	UVP83443.1			1
NXW85_10060		Bacteroides caccae BFG-104	UVQ08240.1			1
NXW85_05905		Bacteroides caccae BFG-104	UVQ07544.1			2
NXW23_02620		Bacteroides caccae BFG-474	UVQ97286.1			2
NXW23_08915		Bacteroides caccae BFG-474	UVQ98410.1			1
INE72_00765		Bacteroides caccae CL03T12C61	QUU06731.1			2
INE72_02233		Bacteroides caccae CL03T12C61	QUU08180.1			1
I6I54_01520		Bacteroides caccae FDAARGOS_1097	QQT78475.1			2
I6I54_14475		Bacteroides caccae FDAARGOS_1097	QQT77462.1			1
I6I54_13490		Bacteroides caccae FDAARGOS_1097	QQT77279.1			1
I6J49_14540		Bacteroides caccae FDAARGOS_1219	QRP57294.1			1
I6J49_15525		Bacteroides caccae FDAARGOS_1219	QRP57476.1			1
I6J49_09130		Bacteroides caccae FDAARGOS_1219	QRP59640.1			2
RJT08_09520		Bacteroides caccae H-1617	WOG13288.1			1
RJT08_03870		Bacteroides caccae H-1617	WOG12235.1			2
A4V03_03285		Bacteroides caecimuris I48	ANU59648.1 QQR18435.1 UQA31454.1			1
K6V21_13575		Bacteroides cellulosilyticus BFG-250	UBD67504.1			1
NXW88_15305		Bacteroides cellulosilyticus BFG-371	UVP53790.1			1
INE78_04735		Bacteroides cellulosilyticus CL06T03C01	QUT92712.1			1
NWT25_13750		Bacteroides cellulosilyticus PL2022	UWZ91982.1			1
endo-hyaluronan lyase (BcellWH2_04512; BACWH2_4253)	4.2.2.1	Bacteroides cellulosilyticus WH2	ALJ61728.1	A0A0P0GKX0		1
HMPREF9445_03068		Bacteroides clarus YIT 12056	EGF49696.1			1
K6V30_10575		Bacteroides faecis BFG-108	UBE47211.1			1
NXX87_12290		Bacteroides faecis BFG-467	UVS36779.1			1
NXY18_10400		Bacteroides faecis BFG-493	UVQ61702.1			1
NXW99_11495		Bacteroides faecis BFG-513	UVS50806.1			1
NXY30_11940		Bacteroides faecis BFG-527	UVQ77022.1			1
NXW26_12330		Bacteroides faecis BFG-554	UVR67473.1			1
NXW58_12535		Bacteroides faecis BFG-624	UVP35561.1			1
KQP61_01545		Bacteroides faecis WAL8736	UYU57328.1			1
BacF7301_11905		Bacteroides faecium CBA7301	QIU94803.1			1
BacF7301_07715		Bacteroides faecium CBA7301	QIU94039.1			2
BacF7301_03615		Bacteroides faecium CBA7301	QIU93291.1			2
BFAG_02638		Bacteroides fragilis 3_1_12	EFR53941.1			1
BF638R_0389		Bacteroides fragilis 638R	CBW20986.1			1
NC657_13010		Bacteroides fragilis 86-5443-2-2	USA55989.1			1
MB0529_00320		Bacteroides fragilis BE1	CUA16985.1			1
K6V22_01145		Bacteroides fragilis BFG-1	UBF17145.1			1
NXW51_05540		Bacteroides fragilis BFG-13	UVQ03555.1			1
NXV04_05360		Bacteroides fragilis BFG-14	UVP07955.1			1
NXX28_05205		Bacteroides fragilis BFG-16	UVO83121.1			1
NXV54_05310		Bacteroides fragilis BFG-17	UVP86758.1			1
NXY24_05305		Bacteroides fragilis BFG-18	UVP16769.1			1
NXY03_05170		Bacteroides fragilis BFG-23	UVQ56528.1			1
NXW55_05285		Bacteroides fragilis BFG-300	UVS00994.1			1
NXW06_04910		Bacteroides fragilis BFG-310	UVP95037.1			1
NXX17_05405		Bacteroides fragilis BFG-317	UVR19148.1			1
NXW10_06080		Bacteroides fragilis BFG-403	UVO62304.1			1
NXV32_05380		Bacteroides fragilis BFG-435	UVO86875.1			1
NXV34_05855		Bacteroides fragilis BFG-448	UVP91083.1			1
NXY37_05885		Bacteroides fragilis BFG-481	UVQ89312.1			1
NXW39_05205		Bacteroides fragilis BFG-49	UVO90979.1			1
NXX63_05645		Bacteroides fragilis BFG-502	UVR71147.1			1
NXV19_05280		Bacteroides fragilis BFG-504	UVQ16198.1			1
NXV41_05425		Bacteroides fragilis BFG-506	UVS22210.1			1
NXW33_05765		Bacteroides fragilis BFG-509	UVP65745.1			1
NXW46_05460		Bacteroides fragilis BFG-518	UVR30732.1			1
NXV60_02665		Bacteroides fragilis BFG-526	UVS39963.1			1
NXW36_05830		Bacteroides fragilis BFG-536	UVS30822.1			1
NXV70_04905		Bacteroides fragilis BFG-539	UVR61579.1			1
NXY10_05815		Bacteroides fragilis BFG-57	UVR34916.1			1
NXY12_05725		Bacteroides fragilis BFG-584	UVQ52491.1			1
NXV67_05145		Bacteroides fragilis BFG-604	UVR83683.1			1
NXW60_03210		Bacteroides fragilis BFG-612	UVV56698.1			1
NXX88_05375		Bacteroides fragilis BFG-634	UVQ20066.1			1
NXW69_05350		Bacteroides fragilis BFG-640	UVP69629.1			1
NXV98_06295		Bacteroides fragilis BFG-642	UVR49161.1			1
NXW83_05030		Bacteroides fragilis BFG-7	UVR87789.1			1
NXX45_05415		Bacteroides fragilis BFG-70	UVR57498.1			1
NXX67_05815		Bacteroides fragilis BFG-79	UVS05337.1			1
NXV17_05535		Bacteroides fragilis BFG-85	UVP38988.1			1
NXW54_05415		Bacteroides fragilis BFG-89	UVO79205.1			1
NXX84_05140		Bacteroides fragilis BFG-9	UVR53216.1			1
NXX30_05625		Bacteroides fragilis BFG-95	UVP99296.1			1
VU15_01225		Bacteroides fragilis BOB25	AKA50465.1			1
E0L14_05850		Bacteroides fragilis CCUG4856T	QCT76950.1			1
INE73_03779		Bacteroides fragilis CL03T12C07	QUU05427.1			1
EC81_005755		Bacteroides fragilis DCMOUH0017B	QCQ53359.1			1
EE52_005455		Bacteroides fragilis DCMOUH0018B	QCQ48905.1			1
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