Activities in Family	Hyaluronate lyase (EC 4.2.2.1); Gellan lyase (EC 4.2.2.25); Chondroitin AC lyase (EC 4.2.2.5);
Mechanism	b-elimination
Note	This family groups together polysaccharide lyases active on hyaluronan, gellan and chondroitin sulfate (Helbert et al., PNAS (2019) [PMID=30850540])
Statistics	GenBank accession (1051); Uniprot accession (5);

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
NYE86_19110		Actinacidiphila bryophytorum DS3	UWE10614.1			1
UA74_24170		Actinoalloteichus fjordicus ADI127-7	APU16852.1			1
AHOG_22060 (fragment)		Actinoalloteichus hoggarensis DSM 45943	ASO22027.1			1
C1701_02955 (fragment)		Actinoalloteichus sp. AHMU CJ021	AUS81420.1			2
UA75_24675		Actinoalloteichus sp. GBA129-24	APU22917.1			1
EF847_15465		Actinobacteria bacterium YIM 96077	AYY15566.1			1
Athai_18320		Actinocatenispora thailandica NBRC 105041	BCJ34329.1			1
BKM31_16855		[Actinomadura] parvosata subsp. kistnae ATCC 55076	AQZ62906.1			2
SAMN04489716_3146		Actinoplanes derwentensis DSM 43941	SDT28879.1			1
Aiant_65520		Actinoplanes ianthinogenes NBRC 13996	BCJ45895.1			1
ACTOB_002127		Actinoplanes oblitus NRRL 3884	WIM98525.1			1
Q0Z83_051910		Actinoplanes sichuanensis 03-723	BEL07000.1			1
L3i22_021900		Actinoplanes sp. L3-i22	BCY07102.1			1
TPMA0078_19360		Actinoplanes sp. TPMA0078	BFD50532.1			1
SAMN04489717_2394		Actinopolymorpha singaporensis DSM 22024	SDS34422.1			1
G6M09_019945		Agrobacterium fabacearum A47a	WCK21287.1			1
G6L97_20395		Agrobacterium fabacearum G3/79	WCA71720.1			1
J5285_16020		Agrobacterium larrymoorei AF3.44	QYA08917.1			1
CFBP5473_15275		Agrobacterium larrymoorei CFBP5473	QCI99375.1			1
CFBP5477_021205		Agrobacterium larrymoorei CFBP5477	WHA43737.1			1
PX860_24725		Agrobacterium leguminum AT13	WLE00268.1			1
CFBP4996_19230		Agrobacterium leguminum CFBP4996	WFS68152.1			1
G6M88_16840		Agrobacterium rubi W2/73	QTG02105.1			1
CFBP5507_19055		Agrobacterium salinitolerans CFBP5507	UYZ09770.1			1
KHC17_05675		Agrobacterium salinitolerans DG3-1	QXC47855.1			1
HRS00_15200		Agrobacterium sp. B19.1.4	UHS58276.1			1
AGROH133_13254		Agrobacterium sp. H13-3	ADY67344.1			1
At12D1_37210		Agrobacterium tumefaciens 12D1	AYM83605.1			1
G6M16_020080		Agrobacterium tumefaciens 14-818c	WCA61430.1			1
DC439_18700		Agrobacterium tumefaciens 183	QAA99793.1			1
CG010_019420		Agrobacterium tumefaciens 186	QDY96335.1			1
At1D1460_36510		Agrobacterium tumefaciens 1D1460	AYM07892.1			1
At1D1609_38680		Agrobacterium tumefaciens 1D1609	AVH43918.1			1
G6M15_11620		Agrobacterium tumefaciens A74a	WCJ62067.1			1
IAI05_18700		Agrobacterium tumefaciens BIM B-1315G	QNP81988.1			1
J8N08_20050		Agrobacterium tumefaciens BIM B-441	QTQ85224.1			1
FY129_19895		Agrobacterium tumefaciens But002	UXT99730.1			1
CFBP5499_22560		Agrobacterium tumefaciens CFBP5499	QCL76208.1			1
CFBP5506_16895		Agrobacterium tumefaciens CFBP5506	WGM61332.1			1
CFBP5877_21815		Agrobacterium tumefaciens CFBP5877	QCL81724.1			1
CFBP7129_19180		Agrobacterium tumefaciens CFBP7129	QCL96364.1			1
EML4_18380		Agrobacterium tumefaciens EML4	QLG24355.1			1
FY132_20220		Agrobacterium tumefaciens Gle001	UXT76679.1			1
FY133_18540		Agrobacterium tumefaciens Gle002	UXT67637.1			1
U0027_18675		Agrobacterium tumefaciens HAMBI_0105	WQE42245.1			1
FY136_20515		Agrobacterium tumefaciens Kin002	UXT51630.1			1
FY137_19390		Agrobacterium tumefaciens Kin003	UXT43422.1			1
G6L31_020720		Agrobacterium tumefaciens LMG 292	WCK05026.1			1
MLE07_19050		Agrobacterium tumefaciens LN-1	UNZ52874.1			1
G6L90_20115		Agrobacterium tumefaciens O54/95	WHO23944.1			1
FY138_20125		Agrobacterium tumefaciens SJ001	UXT35726.1			1
FY139_05500		Agrobacterium tumefaciens SJ002	UXT25024.1			1
FY140_04665		Agrobacterium tumefaciens SJ003	UXT20057.1			1
FY141_20155		Agrobacterium tumefaciens Sta002	UXT15911.1			1
FY142_18815		Agrobacterium tumefaciens Sta003	UXT04289.1			1
FY144_19140		Agrobacterium tumefaciens Sta005	UXS88339.1			1
FY145_19075		Agrobacterium tumefaciens Sut001	UXS80330.1			1
FY146_20145		Agrobacterium tumefaciens Sut002	UXS72835.1			1
FY147_18915		Agrobacterium tumefaciens Teh001	UXS66081.1			1
FY148_20280		Agrobacterium tumefaciens Teh002	UXS55848.1			1
FY149_04780		Agrobacterium tumefaciens Tul001	UXS46582.1			1
FY150_19620		Agrobacterium tumefaciens Tul002	UXS41963.1			1
FY153_18490		Agrobacterium tumefaciens Tul004	UXS27552.1			1
FY154_18455		Agrobacterium tumefaciens Yol001	UXS18998.1			1
FY155_18460		Agrobacterium tumefaciens Yol002	UXS11631.1			1
FY157_16875		Agrobacterium tumefaciens Yub002	UXR93388.1			1
HRR99_15410		Agrobacterium vaccinii B7.6	UHS64218.1			1
AVCG678_23860		Agrobacterium vitis CG678	UJL80737.1			1
AVCG78_23865		Agrobacterium vitis CG78	UJL85950.1			1
K4831_26220		Agrobacterium vitis F2/5	QZO07675.1			1
AVF2S5_23230		Agrobacterium vitis F2/5	UJL91014.1			1
G6L01_025405		Agrobacterium vitis T60/94	WEO74844.1			1
RvVAR031_pl01790		Agrobacterium vitis VAR03-1	BCH56848.1			1
RvVAR0630_pl02390		Agrobacterium vitis VAR06-30	BCH62097.1			1
RvVAT039_pl05310		Agrobacterium vitis VAT03-9	BCH67698.1			1
FLP10_06325		Agromyces intestinalis KACC 19306	QEO14081.1			1
QET93_003795		Akkermansia sp. N21116	WPX41225.1			1
NZD89_22650		Alicyclobacillus fastidiosus DSM 17978	WAH41053.1			1
NZD89_11475		Alicyclobacillus fastidiosus DSM 17978	WAH43945.1			1
AL1_00210		Alistipes shahii WAL 8301	CBK62760.1			1
NQ492_05175		Alistipes shahii WAL 8301	UWN69269.1			1
Avi_7349		Allorhizobium ampelinum S4	ACM40014.1			1
ISP_003449		Amycolatopsis mediterranei ISP5501	UZF70256.1			1
B737_3161		Amycolatopsis mediterranei RB	AGT83825.1			1
RAM_16245		Amycolatopsis mediterranei S699	AEK41737.1			1
AMES_3161		Amycolatopsis mediterranei S699	AFO76697.1			1
AMED_3195		Amycolatopsis mediterranei U32	ADJ44986.1			1
QRY02_05725		Amycolatopsis sp. DG1A-15b	WIX89948.1			1
L3Q65_43305		Amycolatopsis sp. FU40	UKD54619.1			1
HUT10_06170		Amycolatopsis sp. Hca4	QKV73414.1			1
acsn021_34970		Anaerocolumna cellulosilytica SN021	BCJ95928.1			2
Ana3638_09005 (fragment)		Anaerocolumna sedimenticola CBA3638	QHQ60888.1			1
Ana3638_09010 (fragment)		Anaerocolumna sedimenticola CBA3638	QHQ60889.1			1
R2R35_04325		Anaerocolumna sp. AGMB13020	WOO37730.1			2
R2R35_09170		Anaerocolumna sp. AGMB13020	WOO38659.1			2
bsdcttw_14070		Anaerocolumna sp. CTTW	BCJ98366.1			2
bsdcttw_31040 (fragment)		Anaerocolumna sp. CTTW	BCK00064.1			2
K9M52_10195		Arachidicoccus terrestris 5GH13-10	UAY53852.1			1
MB46_13610		Arthrobacter sp. A3	ALV47663.1			1
F8G81_01540		Arthrobacter sp. CDRTa11	UZX01445.1			1
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