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Polysaccharide Lyase Family 29

Activities in FamilyChondroitinase B (EC 4.2.2.19);
Chondroitin AC lyase (EC 4.2.2.5);
Mechanism b-elimination
NoteFamily created after Ndeh et al., J. Biol. Chem. (2018) 293:17906-17916 [PMID=30262663] who have shown that the PL29 enzyme BT_3328 of Bacteroides thetaiotaomicron is active on chondroitin sulfate, dermatan sulfate and hyaluronic acid.
Statistics GenBank accession (278); Uniprot accession (1);
Summary
Download PL29 (279) Taxonomic display Characterized (1)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 FGM00_18205   Aggregatimonas sangjinii F202Z8 QCX01953.1    
 AL1_08240   Alistipes shahii WAL 8301 CBK63379.1    
 NQ492_01925   Alistipes shahii WAL 8301 UWN68665.1    
 FJN15_15205   Alteromonas mediterranea AltCH17 QGX63894.1    
 ALT761_04190 (fragment)   Alteromonas sp. 76-1 VEM00403.1    
 D1815_18615   Aquimarina sp. AD1 AXT57664.1    
 FF099_03690   Aquisalinus flavus D11M-2 UNE47221.1    
 Astex_3538   Asticcacaulis excentricus CB 48 ADU15168.1    
 LH365_18010   Asticcacaulis sp. AND118 UDF05735.1    
 OVA03_16650   Asticcacaulis sp. SL142 WAC48295.1    
 CGC64_04200   Bacteroides caccae ATCC 43185 ASM65237.1    
 NQ555_04145   Bacteroides caccae ATCC 43185 UWN79352.1    
 K6V29_15815   Bacteroides caccae BFG-100 UBF11966.1    
 NXX85_03305   Bacteroides caccae BFG-101 UVP82254.1    
 NXW85_03325   Bacteroides caccae BFG-104 UVQ07081.1    
 NXW23_04510   Bacteroides caccae BFG-474 UVQ97632.1    
 INE72_01097   Bacteroides caccae CL03T12C61 QUU07061.1    
 I6I54_00245   Bacteroides caccae FDAARGOS_1097 QQT79786.1    
 I6J49_10410   Bacteroides caccae FDAARGOS_1219 QRP59765.1    
 RJT08_05200   Bacteroides caccae H-1617 WOG12485.1    
 A4V03_19150   Bacteroides caecimuris I48 ANU59428.1
QQR15668.1
UQA28601.1		    
 K6V30_05235   Bacteroides faecis BFG-108 UBE46228.1    
 NXX87_05490 (fragment)   Bacteroides faecis BFG-467 UVS35564.1    
 NXX87_05485 (fragment)   Bacteroides faecis BFG-467 UVS35563.1    
 NXY18_05115 (fragment)   Bacteroides faecis BFG-493 UVQ60781.1    
 NXY18_05120 (fragment)   Bacteroides faecis BFG-493 UVQ60782.1    
 NXY18_05125 (fragment)   Bacteroides faecis BFG-493 UVQ60783.1    
 NXW99_03770   Bacteroides faecis BFG-513 UVS49370.1    
 NXY30_05660 (fragment)   Bacteroides faecis BFG-527 UVQ75879.1    
 NXY30_05665 (fragment)   Bacteroides faecis BFG-527 UVQ75880.1    
 NXW26_05495 (fragment)   Bacteroides faecis BFG-554 UVR66277.1    
 NXW26_05500 (fragment)   Bacteroides faecis BFG-554 UVR66278.1    
 NXW58_07060   Bacteroides faecis BFG-624 UVP34680.1    
 KQP61_01180   Bacteroides faecis WAL8736 UYU57260.1    
 BacF7301_06015   Bacteroides faecium CBA7301 QIU93728.1    
 DYI28_20185   Bacteroides ovatus 3725 D1 iv QDM10828.1    
 Bovatus_03484   Bacteroides ovatus ATCC 8483 ALJ48091.1    
 NQ517_06210   Bacteroides ovatus ATCC 8483 UWN93219.1    
 K6V23_24790   Bacteroides ovatus BFG-107 UBF07577.1    
 NXW74_06920   Bacteroides ovatus BFG-126 UVR10685.1    
 NXW64_07585   Bacteroides ovatus BFG-177 UVO70785.1    
 NXW12_16805 (fragment)   Bacteroides ovatus BFG-179 UVQ30290.1    
 NXW12_16800 (fragment)   Bacteroides ovatus BFG-179 UVQ30289.1    
 NXV93_07010   Bacteroides ovatus BFG-224 UVR44741.1    
 NXU82_06485   Bacteroides ovatus BFG-258 UVQ38731.1    
 NXV29_06895   Bacteroides ovatus BFG-261 UVR39833.1    
 NXX44_06640   Bacteroides ovatus BFG-299 UVQ66036.1    
 NXW52_07120 (fragment)   Bacteroides ovatus BFG-464 UVP12449.1    
 NXW52_07125 (fragment)   Bacteroides ovatus BFG-464 UVP12450.1    
 NXW19_07140   Bacteroides ovatus BFG-465 UVP78564.1    
 INE80_00830   Bacteroides ovatus CL06T03C20 QUT78855.1    
 OU990_26480   Bacteroides ovatus CP926 WII03947.1    
 I6J65_15490   Bacteroides ovatus FDAARGOS_1235 QRQ54963.1    
 FOC41_18710   Bacteroides ovatus FDAARGOS_733 QGT72857.1    
 RJT06_14655   Bacteroides ovatus H-1813 MDV3117781.1    
 BACOV975_01264   Bacteroides ovatus V975 SCV07501.1    
 BOVAC1_78   Bacteroides ovatus VPIC145 CAG9865715.1    
 NQ505_03730   Bacteroides sp. D2 UWO00550.1    
 KQP79_05570   Bacteroides sp. DH3716P UYU37528.1    
 H8796_06825   Bacteroides sp. M10 QNL40303.1    
 Btheta7330_04972   Bacteroides thetaiotaomicron 7330 ALJ44486.1    
 NFE52_04190   Bacteroides thetaiotaomicron B2 WWE55556.1    
 NXV79_03745   Bacteroides thetaiotaomicron BFG-109 UVP61537.1    
 NXX00_05865   Bacteroides thetaiotaomicron BFG-116 UVV81606.1    
 NXY23_05155   Bacteroides thetaiotaomicron BFG-119 UVS54410.1    
 NXX57_05635   Bacteroides thetaiotaomicron BFG-129 UVP57353.1    
 NXV61_06295   Bacteroides thetaiotaomicron BFG-130 UVR92619.1    
 NXX60_16485   Bacteroides thetaiotaomicron BFG-148 UVQ21447.1    
 NXY45_05150   Bacteroides thetaiotaomicron BFG-169 UVP43250.1    
 NXX51_04490   Bacteroides thetaiotaomicron BFG-264 UVS13947.1    
 NXY38_05780   Bacteroides thetaiotaomicron BFG-266 UVV86093.1    
 NXY15_07135 (fragment)   Bacteroides thetaiotaomicron BFG-357 UVV54175.1    
 NXY15_07140 (fragment)   Bacteroides thetaiotaomicron BFG-357 UVV54176.1    
 NXW43_05470   Bacteroides thetaiotaomicron BFG-446 UVO74865.1    
 NXY16_05620   Bacteroides thetaiotaomicron BFG-478 UVS26549.1    
 NXW22_05625   Bacteroides thetaiotaomicron BFG-484 UVP29825.1    
 NXV46_06030   Bacteroides thetaiotaomicron BFG-498 UVQ43258.1    
 NXY28_16310 (fragment)   Bacteroides thetaiotaomicron BFG-505 UVV57931.1    
 NXY28_16305 (fragment)   Bacteroides thetaiotaomicron BFG-505 UVV57930.1    
 NXW82_04535   Bacteroides thetaiotaomicron BFG-510 UVQ28063.1    
 K6V27_05125   Bacteroides thetaiotaomicron BFG-55 UBD12989.1    
 NXX83_06215   Bacteroides thetaiotaomicron BFG-576 UVQ70850.1    
 INE82_04261   Bacteroides thetaiotaomicron CL06T03C18 QUT73426.1    
 INE89_03448   Bacteroides thetaiotaomicron CL11T00C24 QUT41236.1    
 KHO74_02066   Bacteroides thetaiotaomicron CL15T119C52 QZU86094.1    
 KHO73_02044   Bacteroides thetaiotaomicron CL15T12C11 QZU80657.1    
 V3C11_03970   Bacteroides thetaiotaomicron DFI.6.40 WVP68070.1    
 FE838_06485   Bacteroides thetaiotaomicron DSM 2079 QMW85724.1    
 BatF92_45820   Bacteroides thetaiotaomicron F9-2 BCA52640.1    
 I6G92_00980   Bacteroides thetaiotaomicron FDAARGOS_935 QQA08546.1    
 RJT07_14775   Bacteroides thetaiotaomicron H-2209 WOG18427.1    
 RJT03_07855   Bacteroides thetaiotaomicron H-2622 WOG44314.1    
 MJ393_05970   Bacteroides thetaiotaomicron VPI 5482 UML62617.1    
 KQP69_15290   Bacteroides thetaiotaomicron VPI-2808B UYU98987.1    
 KQP56_16680   Bacteroides thetaiotaomicron VPI-3164 UYU94262.1    
 KQP74_05530   Bacteroides thetaiotaomicron VPI-3443 UYU92092.1    
 chondroitin ABC lyase (BT_3328; BT3328) 4.2.2.19
4.2.2.5		 Bacteroides thetaiotaomicron VPI-5482 AAO78434.1 Q8A2H7  
 KP721_17285   Bacteroides thetaiotaomicron VPI-5482A UYU84946.1    
 KQP77_14870   Bacteroides thetaiotaomicron VPI-BT7853 UYU79765.1    
 KQP72_25370   Bacteroides thetaiotaomicron VPI-BT8702 UYU76346.1    
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