Activities in Family	Glucuronic ulvan lyase (EC 4.2.2.-); Iduronic ulvan lyase (EC 4.2.2.-);
Mechanism	b-elimination
3D Structure Status	7-bladed β-propeller
Note	Family created after Kopel et al. (2016) J. Biol. Chem., 291, 5871-5878 [PMID=26763234]. Ulvan lyases cleave the bond between 3-sulfated rhamnose (Rha3S) linked to either D-glucuronic acid (GlcA) or L-iduronic acid (IduA) in the marine polysaccharide ulvan. Members of this family are known to specifically cleave the b(1,4) glycosidic bond between GlcUA and R3S residues by b-elimination.
Statistics	GenBank accession (62); Uniprot accession (6); PDB accession (6); 3D entries (2); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
glucuronic specific ulvan lyase (AsPL; LOR_107)	4.2.2.-	Alteromonas sp. LOR	AMA19991.1	A0A109PTH9	6BYP[A,B] 1.90 6BYT[A,B] α-L-4-deoxy-IdopA-(1-4)-α-L-Rhap3SO3-(1-4)-β-D-GlcpA-(1-4)-α-L-Rhap3SO3 β-D-4-deoxy-GlcpA-(1-4)-α-L-Rhap3SO3-(1-4)-β-D-GlcpA-(1-4)-α-L-Rhap3SO3 2.20 6BYX[A,B] α-L-4-deoxy-IdopA-(1-4)-α-L-Rhap3SO3-(1-4)-β-D-GlcpA-(1-4)-α-L-Rhap3SO3 2.21 6JQ9[A,B] 1.81
ulvan lyase (Uly1 ; XM47_11230)	4.2.2.-	Catenovulum maritimum Q1	KMT65093.1 WP_053084548.1	A0A0J8GWN9	7CZH[A,B] 2.10 7DRQ[A,B] 1.79
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