Polysaccharide Lyase Family 24

Activities in FamilyGlucuronic ulvan lyase (EC 4.2.2.-);
Iduronic ulvan lyase (EC 4.2.2.-);
Mechanism b-elimination
3D Structure Status7-bladed β-propeller
NoteFamily created after Kopel et al. (2016) J. Biol. Chem., 291, 5871-5878 [PMID=26763234]. Ulvan lyases cleave the bond between 3-sulfated rhamnose (Rha3S) linked to either D-glucuronic acid (GlcA) or L-iduronic acid (IduA) in the marine polysaccharide ulvan. Members of this family are known to specifically cleave the b(1,4) glycosidic bond between GlcUA and R3S residues by b-elimination.
Statistics GenBank accession (62); Uniprot accession (6); PDB accession (6); 3D entries (2); cryst (0)
Bacteria
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 ulvan lyase (UllA) 4.2.2.-
4.2.2.-
pubmed
pubmed
pubmed
pubmed
Alteromonas sp. KUL17 BAY00694.1 A0A1Z4F647  
 glucuronic specific ulvan lyase (AsPL; LOR_107) 4.2.2.- pubmed
Alteromonas sp. LOR AMA19991.1 A0A109PTH9 6BYP[A,B]
6BYT[A,B]
6BYX[A,B]
6JQ9[A,B]
 glucuronic specific ulvan lyase (LOR_61) 4.2.2.- pubmed
Alteromonas sp. LOR WP_032096165.1 P9WF07  
 ulvan lyase (Uly1 ; XM47_11230) 4.2.2.- pubmed
Catenovulum maritimum Q1 KMT65093.1
WP_053084548.1
A0A0J8GWN9 7CZH[A,B]
7DRQ[A,B]
 glucuronic specific ulvan lyase (PLSV_3875) 4.2.2.- pubmed
Pseudoalteromonas sp. PLSV AMA19992.1 A0A0X9SHN5  
 glucuronic specific ulvan lyase (PLSV_3925) 4.2.2.- pubmed
Pseudoalteromonas sp. PLSV WP_033186955.1 P9WF06  
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